1BYN
| SOLUTION STRUCTURE OF THE CALCIUM-BOUND FIRST C2-DOMAIN OF SYNAPTOTAGMIN I | 分子名称: | CALCIUM ION, PROTEIN (SYNAPTOTAGMIN I) | 著者 | Shao, X, Fernandez, I, Sudhof, T.C, Rizo, J. | 登録日 | 1998-10-18 | 公開日 | 1998-10-21 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the Ca2+-free and Ca2+-bound C2A domain of synaptotagmin I: does Ca2+ induce a conformational change? Biochemistry, 37, 1998
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6IJB
| Structure of 3-methylmercaptopropionate CoA ligase mutant K523A in complex with AMP and MMPA | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-(methylsulfanyl)propanoic acid, ADENOSINE MONOPHOSPHATE, ... | 著者 | Shao, X, Cao, H.Y, Wang, P, Li, C.Y, Zhao, F, Peng, M, Chen, X.L, Zhang, Y.Z. | 登録日 | 2018-10-09 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.111 Å) | 主引用文献 | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria. Mol.Microbiol., 111, 2019
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6IJC
| Structure of MMPA-CoA dehydrogenase from Roseovarius nubinhibens ISM | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Acyl-CoA dehydrogenase family protein | 著者 | Shao, X, Yuan, Z.L, Cao, H.Y, Wang, P, Li, C.Y, Chen, X.L, Zhang, Y.Z. | 登録日 | 2018-10-09 | 公開日 | 2019-07-03 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria. Mol.Microbiol., 111, 2019
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6IHK
| Structure of MMPA CoA ligase in complex with ADP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AMP-binding domain protein | 著者 | Shao, X, Cao, H.Y, Wang, P, Li, C.Y, Zhao, F, Peng, M, Chen, X.L, Zhang, Y.Z. | 登録日 | 2018-09-30 | 公開日 | 2019-07-03 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Mechanistic insight into 3-methylmercaptopropionate metabolism and kinetical regulation of demethylation pathway in marine dimethylsulfoniopropionate-catabolizing bacteria. Mol.Microbiol., 111, 2019
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5XA5
| Crystal structure of HMP-1-HMP-2 complex | 分子名称: | Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2 | 著者 | Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J. | 登録日 | 2017-03-11 | 公開日 | 2017-08-30 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface. J.Biol.Chem., 292, 2017
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2KC5
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6CAA
| CryoEM structure of human SLC4A4 sodium-coupled acid-base transporter NBCe1 | 分子名称: | Electrogenic sodium bicarbonate cotransporter 1 | 著者 | Huynh, K.W, Jiang, J, Abuladze, N, Tsirulnikov, K, Kao, L, Shao, X, Newman, D, Azimov, R, Pushkin, A, Zhou, Z.H, Kurtz, I. | 登録日 | 2018-01-29 | 公開日 | 2018-03-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1. Nat Commun, 9, 2018
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7B7H
| The glucuronoyl esterase OtCE15A R268A variant from Opitutus terrae in complex with, and covalently linked to, D-glucuronate | 分子名称: | 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, GLYCINE, ... | 著者 | Mazurkewich, S, Larsbrink, J, Lo Leggio, L. | 登録日 | 2020-12-10 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Mechanism and biomass association of glucuronoyl esterase: an alpha / beta hydrolase with potential in biomass conversion. Nat Commun, 13, 2022
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2YYF
| Purification and structural characterization of a D-amino acid containing conopeptide, marmophine, from Conus marmoreus | 分子名称: | M-conotoxin mr12 | 著者 | Huang, F, Du, W, Han, Y, Wang, C. | 登録日 | 2007-04-29 | 公開日 | 2008-04-08 | 最終更新日 | 2022-03-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Purification and structural characterization of a D-amino acid-containing conopeptide, conomarphin, from Conus marmoreus. Febs J., 275, 2008
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4C13
| x-ray crystal structure of Staphylococcus aureus MurE with UDP-MurNAc- Ala-Glu-Lys | 分子名称: | CHLORIDE ION, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Ruane, K.M, Roper, D.I, Fulop, V, Barreteau, H, Boniface, A, Dementin, S, Blanot, D, Mengin-Lecreulx, D, Gobec, S, Dessen, A, Dowson, C.G, Lloyd, A.J. | 登録日 | 2013-08-09 | 公開日 | 2013-10-02 | 最終更新日 | 2021-03-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy. Nat.Chem.Biol., 2021
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6NRH
| Crystal Structure of human PARP-1 ART domain bound inhibitor UTT63 | 分子名称: | 3-hydroxy-2-({4-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRJ
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT93 | 分子名称: | (2Z)-2-[(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)methylidene]-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRG
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT57 | 分子名称: | 2-{[3-fluoro-4-(1H-tetrazol-5-yl)phenyl]methyl}-3-hydroxy-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NRF
| Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT103 | 分子名称: | 2-({4-[4-(1H-benzimidazol-2-yl)piperazine-1-carbonyl]phenyl}methyl)-3-hydroxy-1-benzofuran-7-carboxamide, CHLORIDE ION, CITRIC ACID, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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1JCK
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1AC6
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1KB5
| MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX | 分子名称: | ANTIBODY DESIRE-1, KB5-C20 T-CELL ANTIGEN RECEPTOR | 著者 | Housset, D, Mazza, G, Gregoire, C, Piras, C, Malissen, B, Fontecilla-Camps, J.C. | 登録日 | 1997-04-06 | 公開日 | 1998-04-08 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. EMBO J., 16, 1997
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4X9Z
| Dimeric conotoxin alphaD-GeXXA | 分子名称: | alphaD-conotoxin GeXXA from the venom of Conus generalis | 著者 | Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C. | 登録日 | 2014-12-12 | 公開日 | 2015-12-02 | 最終更新日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors Sci Rep, 5, 2015
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4XZ6
| TmoX in complex with TMAO | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, GLYCEROL, ... | 著者 | Zhang, Y.Z, Li, C.Y. | 登録日 | 2015-02-04 | 公開日 | 2015-08-19 | 最終更新日 | 2015-10-28 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Mechanistic Insight into Trimethylamine N-Oxide Recognition by the Marine Bacterium Ruegeria pomeroyi DSS-3 J.Bacteriol., 197, 2015
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2LMZ
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2JQC
| A L-amino acid mutant of a D-amino acid containing conopeptide | 分子名称: | L-mr12 | 著者 | Huang, F, Du, W, Han, Y, Wang, C, Chi, C. | 登録日 | 2007-05-31 | 公開日 | 2008-04-15 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Purification and structural characterization of a d-amino acid-containing conopeptide, conomarphin, from Conus marmoreus Febs J., 275, 2008
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6AK1
| Crystal structure of DmoA from Hyphomicrobium sulfonivorans | 分子名称: | Dimethyl-sulfide monooxygenase | 著者 | Cao, H.Y, Wang, P, Peng, M, Li, C.Y. | 登録日 | 2018-08-28 | 公開日 | 2018-12-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.284 Å) | 主引用文献 | Crystal structure of the dimethylsulfide monooxygenase DmoA from Hyphomicrobium sulfonivorans. Acta Crystallogr.,Sect.F, 74, 2018
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5H5M
| Crystal structure of HMP-1 M domain | 分子名称: | Alpha-catenin-like protein hmp-1 | 著者 | Kang, H, Bang, I, Weis, W.I, Choi, H.J. | 登録日 | 2016-11-08 | 公開日 | 2017-03-29 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional characterization of Caenorhabditis elegans alpha-catenin reveals constitutive binding to beta-catenin and F-actin J. Biol. Chem., 292, 2017
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7XCZ
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7XDK
| Cryo-EM structure of SARS-CoV-2 Delta Spike protein in complex with BA7054 and BA7125 fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BA7054 fab, ... | 著者 | Liu, Z, Lui, S, Gao, Y. | 登録日 | 2022-03-27 | 公開日 | 2023-03-01 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Biparatopic antibody BA7208/7125 effectively neutralizes SARS-CoV-2 variants including Omicron BA.1-BA.5. Cell Discov, 9, 2023
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