8YQQ
| Structure of HKU1B RBD with TMPRSS2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, Transmembrane protease serine 2 | Authors: | Gao, X, Cui, S, Ding, W, Zhu, K, Shang, K, Zhu, H. | Deposit date: | 2024-03-19 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.95 Å) | Cite: | Structural basis for the interaction between human coronavirus HKU1 spike receptor binding domain and its receptor TMPRSS2. Cell Discov, 10, 2024
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8YOY
| Structure of HKU1A RBD with TMPRSS2 | Descriptor: | Spike protein S1, Transmembrane protease serine 2 | Authors: | Gao, X, Cui, S, Ding, W, Shang, K, Zhu, H, Zhu, K. | Deposit date: | 2024-03-14 | Release date: | 2024-08-28 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Structural basis for the interaction between human coronavirus HKU1 spike receptor binding domain and its receptor TMPRSS2. Cell Discov, 10, 2024
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8IT0
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-2) | Descriptor: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | Authors: | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | Deposit date: | 2023-03-21 | Release date: | 2023-10-18 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8ISZ
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA monomer | Descriptor: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | Authors: | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | Deposit date: | 2023-03-21 | Release date: | 2023-10-18 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8ISY
| Cryo-EM structure of free-state Crt-SPARTA | Descriptor: | Piwi domain-containing protein, TIR domain-containing protein | Authors: | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | Deposit date: | 2023-03-21 | Release date: | 2023-10-18 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.27 Å) | Cite: | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8IT1
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA tetramer (NADase active form) | Descriptor: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | Authors: | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | Deposit date: | 2023-03-21 | Release date: | 2023-11-08 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8K9G
| Cryo-EM structure of Crt-SPARTA-gRNA-tDNA dimer (conformation-1) | Descriptor: | DNA (45-mer), Piwi domain-containing protein, RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*AP*GP*U)-3'), ... | Authors: | Gao, X, Shang, K, Zhu, K, Wang, L, Mu, Z, Fu, X, Yu, X, Qin, B, Zhu, H, Ding, W, Cui, S. | Deposit date: | 2023-08-01 | Release date: | 2023-10-18 | Last modified: | 2024-02-07 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Nucleic-acid-triggered NADase activation of a short prokaryotic Argonaute. Nature, 625, 2024
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8X8Q
| Structure of enterovirus protease in complex host factor | Descriptor: | 2A protein (Fragment), Actin-histidine N-methyltransferase, ZINC ION | Authors: | Gao, X, Cui, S. | Deposit date: | 2023-11-28 | Release date: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.14 Å) | Cite: | The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction. Nat Commun, 15, 2024
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8X77
| Enterovirus proteinase with host factor | Descriptor: | 2A protein, Actin-histidine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Gao, X, Cui, S. | Deposit date: | 2023-11-23 | Release date: | 2024-05-29 | Method: | X-RAY DIFFRACTION (3.52 Å) | Cite: | The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction. Nat Commun, 15, 2024
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6WAA
| K. pneumoniae Topoisomerase IV (ParE-ParC) in complex with DNA and compound 34 (7-[(1S,5R)-1-amino-3-azabicyclo[3.1.0]hexan-3-yl]-4-(aminomethyl)-1-cyclopropyl-3,6-difluoro-8-methylquinolin-2(1H)-one) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 7-[(1S,5R)-1-amino-3-azabicyclo[3.1.0]hexan-3-yl]-4-(aminomethyl)-1-cyclopropyl-3,6-difluoro-8-methylquinolin-2(1H)-one, CHLORIDE ION, ... | Authors: | Noeske, J, Shu, W, Bellamacina, C. | Deposit date: | 2020-03-24 | Release date: | 2020-07-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria. J.Med.Chem., 63, 2020
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