2QTL
| Crystal Structure of the FAD-containing FNR-like Module of Human Methionine Synthase Reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase | 著者 | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2007-08-02 | 公開日 | 2007-11-13 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
|
|
2QTZ
| Crystal Structure of the NADP+-bound FAD-containing FNR-like Module of Human Methionine Synthase Reductase | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Methionine synthase reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Wolthers, K.R, Lou, X, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2007-08-02 | 公開日 | 2007-11-13 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism of Coenzyme Binding to Human Methionine Synthase Reductase Revealed through the Crystal Structure of the FNR-like Module and Isothermal Titration Calorimetry Biochemistry, 46, 2007
|
|
2R14
| Structure of morphinone reductase in complex with tetrahydroNAD | 分子名称: | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, Morphinone reductase | 著者 | Costello, C.L, Scrutton, N.S, Leys, D. | 登録日 | 2007-08-22 | 公開日 | 2008-07-01 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms. J.Am.Chem.Soc., 129, 2007
|
|
4CSZ
| STRUCTURE OF F306C MUTANT OF NITRITE REDUCTASE FROM Achromobacter XYLOSOXIDANS WITH NITRITE BOUND | 分子名称: | COPPER (II) ION, DI(HYDROXYETHYL)ETHER, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ... | 著者 | Leferink, N.G.H, Antonyuk, S.V, Houwman, J.A, Scrutton, N.S, REady, R, Hasnain, S.S. | 登録日 | 2014-03-11 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Impact of Residues Remote from the Catalytic Centre on Enzyme Catalysis of Copper Nitrite Reductase. Nat.Commun., 5, 2014
|
|
4CSP
| Structure of the F306C mutant of nitrite reductase from Achromobacter xylosoxidans | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, COPPER (II) ION, DISSIMILATORY COPPER-CONTAINING NITRITE REDUCTASE, ... | 著者 | Leferink, N.G.H, Antonyuk, S.V, Houwman, J.A, Scrutton, N.S, REady, R, Hasnain, S.S. | 登録日 | 2014-03-09 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Impact of Residues Remote from the Catalytic Centre on Enzyme Catalysis of Copper Nitrite Reductase. Nat.Commun., 5, 2014
|
|
3KP1
| Crystal structure of ornithine 4,5 aminomutase (Resting State) | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, D-ornithine aminomutase E component, ... | 著者 | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | 登録日 | 2009-11-14 | 公開日 | 2010-01-26 | 最終更新日 | 2019-10-30 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
|
|
3KOW
| Crystal Structure of ornithine 4,5 aminomutase backsoaked complex | 分子名称: | 5'-DEOXYADENOSINE, COBALAMIN, D-ornithine aminomutase E component, ... | 著者 | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | 登録日 | 2009-11-14 | 公開日 | 2010-01-26 | 最終更新日 | 2012-10-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
|
|
3KRU
| Crystal Structure of the Thermostable Old Yellow Enzyme from Thermoanaerobacter pseudethanolicus E39 | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, NADH:flavin oxidoreductase/NADH oxidase | 著者 | Adalbjornsson, B.V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2009-11-19 | 公開日 | 2009-12-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme. Chembiochem, 11, 2010
|
|
3KOX
| Crystal Structure of ornithine 4,5 aminomutase in complex with 2,4-diaminobutyrate (Anaerobic) | 分子名称: | (2S)-2-amino-4-{[(1Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}butanoic acid, 5'-DEOXYADENOSINE, COBALAMIN, ... | 著者 | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | 登録日 | 2009-11-14 | 公開日 | 2010-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
|
|
3KOZ
| Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Anaerobic) | 分子名称: | (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ... | 著者 | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | 登録日 | 2009-11-14 | 公開日 | 2010-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
|
|
3KRZ
| Crystal Structure of the Thermostable NADH4-bound old yellow enzyme from Thermoanaerobacter pseudethanolicus E39 | 分子名称: | 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, FLAVIN MONONUCLEOTIDE, NADH:flavin oxidoreductase/NADH oxidase | 著者 | Adalbjornsson, B.V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2009-11-20 | 公開日 | 2009-12-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Biocatalysis with thermostable enzymes: structure and properties of a thermophilic 'ene'-reductase related to old yellow enzyme. Chembiochem, 11, 2010
|
|
3P8J
| |
3P84
| |
3P67
| |
3P74
| |
1S24
| Rubredoxin domain II from Pseudomonas oleovorans | 分子名称: | CADMIUM ION, Rubredoxin 2 | 著者 | Perry, A, Tambyrajah, W, Grossmann, J.G, Lian, L.Y, Scrutton, N.S. | 登録日 | 2004-01-08 | 公開日 | 2004-05-04 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the two-iron rubredoxin of Pseudomonas oleovorans determined by NMR spectroscopy and solution X-ray scattering and interactions with rubredoxin reductase. Biochemistry, 43, 2004
|
|
1T9G
| Structure of the human MCAD:ETF complex | 分子名称: | ADENOSINE MONOPHOSPHATE, Acyl-CoA dehydrogenase, medium-chain specific, ... | 著者 | Toogood, H.S, van Thiel, A, Basran, J, Sutcliffe, M.J, Scrutton, N.S, Leys, D. | 登録日 | 2004-05-17 | 公開日 | 2004-06-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Extensive domain motion and electron transfer in the human electron transferring flavoprotein-medium chain Acyl-CoA dehydrogenase complex J.Biol.Chem., 279, 2004
|
|
5N6G
| NerA from Agrobacterium radiobacter in complex with 2-phenylacrylic acid | 分子名称: | 2-Phenylacrylic acid, ACETATE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2017-02-15 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | 主引用文献 | Structural insights into the ene-reductase synthesis of profens. Org. Biomol. Chem., 15, 2017
|
|
5NX7
| Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate and 2-fluorogeranyl diphosphate | 分子名称: | (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, ... | 著者 | Karuppiah, V, Leys, D, Scrutton, N.S. | 登録日 | 2017-05-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase. ACS Catal, 7, 2017
|
|
5NX4
| |
5N6Q
| Xenobiotic reductase A (XenA) from Pseudomonas putida in complex with 2-phenylacrylic acid | 分子名称: | 2-Phenylacrylic acid, CHLORIDE ION, FLAVIN MONONUCLEOTIDE, ... | 著者 | Karuppiah, V, Toogood, H.S, Leys, D, Scrutton, N.S. | 登録日 | 2017-02-15 | 公開日 | 2017-05-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insights into the ene-reductase synthesis of profens. Org. Biomol. Chem., 15, 2017
|
|
5NX6
| Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate | 分子名称: | (2E)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, 2-ethyl-2-(hydroxymethyl)propane-1,3-diol, ETHYL DIMETHYL AMMONIO PROPANE SULFONATE, ... | 著者 | Karuppiah, V, Leys, D, Scrutton, N.S. | 登録日 | 2017-05-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase. ACS Catal, 7, 2017
|
|
5NX5
| Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus in complex with 2-fluorogeranyl diphosphate | 分子名称: | (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, CHLORIDE ION, GLYCEROL, ... | 著者 | Karuppiah, V, Leys, D, Scrutton, N.S. | 登録日 | 2017-05-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase. ACS Catal, 7, 2017
|
|
2O2K
| Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N | 分子名称: | Methionine synthase | 著者 | Wolthers, K.R, Toogood, H.S, Jowitt, T.A, Marshall, K.R, Leys, D, Scrutton, N.S. | 登録日 | 2006-11-30 | 公開日 | 2006-12-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure and solution characterization of the activation domain of human methionine synthase Febs J., 274, 2007
|
|
1DJQ
| STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF RECOMBINANT C30A MUTANT OF TRIMETHYLAMINE DEHYDROGENASE FROM METHYLOPHILUS METHYLOTROPHUS (SP. W3A1) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, FLAVIN MONONUCLEOTIDE, IRON/SULFUR CLUSTER, ... | 著者 | Trickey, P, Basran, J, Lian, L.-Y, Chen, Z.-W, Barton, J.D, Sutcliffe, M.J, Scrutton, N.S, Mathews, F.S. | 登録日 | 1999-12-03 | 公開日 | 1999-12-22 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural and biochemical characterization of recombinant wild type and a C30A mutant of trimethylamine dehydrogenase from methylophilus methylotrophus (sp. W(3)A(1)). Biochemistry, 39, 2000
|
|