2R14

Structure of morphinone reductase in complex with tetrahydroNAD

Summary for 2R14

Entry DOI	10.2210/pdb2r14/pdb
Related	1gwj
Descriptor	Morphinone reductase, FLAVIN MONONUCLEOTIDE, 1,4,5,6-TETRAHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (4 entities in total)
Functional Keywords	h-tunnelling, flavoprotein, nadh, morphinone reductase, hydride transfer, oxidoreductase
Biological source	Pseudomonas putida
Total number of polymer chains	1
Total formula weight	42414.69
Authors	Costello, C.L.,Scrutton, N.S.,Leys, D. (deposition date: 2007-08-22, release date: 2008-07-01, Last modification date: 2024-02-21)
Primary citation	Pudney, C.R.,Hay, S.,Pang, J.,Costello, C.,Leys, D.,Sutcliffe, M.J.,Scrutton, N.S. Mutagenesis of morphinone reductase induces multiple reactive configurations and identifies potential ambiguity in kinetic analysis of enzyme tunneling mechanisms. J.Am.Chem.Soc., 129:13949-13956, 2007 Cited by PubMed: 17939663 DOI: 10.1021/ja074463h PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation