2O2K

Crystal Structure of the Activation Domain of Human Methionine Synthase Isoform/Mutant D963E/K1071N

Summary for 2O2K

• Entry DOI: 10.2210/pdb2o2k/pdb
• Descriptor: Methionine synthase (2 entities in total)
• Functional Keywords: c-shaped, twisted anti-parallel beta sheet, beta-meander region, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q99707
• Total number of polymer chains: 2
• Total formula weight: 81055.45

Authors

Wolthers, K.R.,Toogood, H.S.,Jowitt, T.A.,Marshall, K.R.,Leys, D.,Scrutton, N.S. (deposition date: 2006-11-30, release date: 2006-12-19, Last modification date: 2023-10-25)

• Primary citation: Wolthers, K.R.,Toogood, H.S.,Jowitt, T.A.,Marshall, K.R.,Leys, D.,Scrutton, N.S.; Crystal structure and solution characterization of the activation domain of human methionine synthase; Febs J., 274:738-750, 2007; PubMed: 17288554; DOI: 10.1111/j.1742-4658.2006.05618.x

Experimental method

X-RAY DIFFRACTION (1.6 Å)