5NX5

Crystal structure of Linalool/Nerolidol synthase from Streptomyces clavuligerus in complex with 2-fluorogeranyl diphosphate

Summary for 5NX5

• Entry DOI: 10.2210/pdb5nx5/pdb
• Descriptor: Pentalenene synthase, MAGNESIUM ION, (2Z)-2-fluoro-3,7-dimethylocta-2,6-dien-1-yl trihydrogen diphosphate, ... (7 entities in total)
• Functional Keywords: terpene synthase, linalool, nerolidol, monoterpenoid, ligase
• Biological source: Streptomyces clavuligerus
• Total number of polymer chains: 2
• Total formula weight: 73882.96

Authors

Karuppiah, V.,Leys, D.,Scrutton, N.S. (deposition date: 2017-05-09, release date: 2017-09-20, Last modification date: 2024-01-17)

• Primary citation: Karuppiah, V.,Ranaghan, K.E.,Leferink, N.G.H.,Johannissen, L.O.,Shanmugam, M.,Ni Cheallaigh, A.,Bennett, N.J.,Kearsey, L.J.,Takano, E.,Gardiner, J.M.,van der Kamp, M.W.,Hay, S.,Mulholland, A.J.,Leys, D.,Scrutton, N.S.; Structural Basis of Catalysis in the Bacterial Monoterpene Synthases Linalool Synthase and 1,8-Cineole Synthase.; ACS Catal, 7:6268-6282, 2017; PubMed: 28966840; DOI: 10.1021/acscatal.7b01924

Experimental method

X-RAY DIFFRACTION (1.82 Å)