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4A11
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BU of 4a11 by Molmil
Structure of the hsDDB1-hsCSA complex
Descriptor: DNA DAMAGE-BINDING PROTEIN 1, DNA EXCISION REPAIR PROTEIN ERCC-8
Authors:Bohm, K, Scrima, A, Fischer, E.S, Gut, H, Thomae, N.H.
Deposit date:2011-09-13
Release date:2011-12-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
6GMG
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BU of 6gmg by Molmil
Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase
Descriptor: CITRATE ANION, DI(HYDROXYETHYL)ETHER, PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE, ...
Authors:Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A.
Deposit date:2018-05-25
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase.
FEBS J., 285, 2018
6FHP
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BU of 6fhp by Molmil
DAIP in complex with a C-terminal fragment of thermolysin
Descriptor: Dispase autolysis-inducing protein, Thermolysin
Authors:Schmelz, S, Fiebig, D, Fuchsbauer, H.L, Blankenfeldt, W, Scrima, A.
Deposit date:2018-01-15
Release date:2018-09-12
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.703 Å)
Cite:Destructive twisting of neutral metalloproteases: the catalysis mechanism of the Dispase autolysis-inducing protein from Streptomyces mobaraensis DSM 40487.
FEBS J., 285, 2018
3CP8
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BU of 3cp8 by Molmil
Crystal structure of GidA from Chlorobium tepidum
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, tRNA uridine 5-carboxymethylaminomethyl modification enzyme gidA
Authors:Meyer, S, Scrima, A, Versees, W, Wittinghofer, A.
Deposit date:2008-03-31
Release date:2008-06-24
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate
J.Mol.Biol., 380, 2008
5OJY
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BU of 5ojy by Molmil
Co-complex structure of regulator protein 2 (PamR2) with pamamycin 607 from Streptomyces alboniger
Descriptor: CITRIC ACID, GLYCEROL, Pamamycin 607, ...
Authors:Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A.
Deposit date:2017-07-24
Release date:2018-04-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Design, development and application of whole-cell based antibiotic-specific biosensor.
Metab. Eng., 47, 2018
5NPV
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BU of 5npv by Molmil
Structure of human ATG5-ATG16L1(ATG5BD) complex (I4)
Descriptor: Autophagy protein 5, Autophagy-related protein 16-1
Authors:Archna, A, Scrima, A.
Deposit date:2017-04-19
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification, biochemical characterization and crystallization of the central region of human ATG16L1.
Acta Crystallogr F Struct Biol Commun, 73, 2017
5NPW
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BU of 5npw by Molmil
Structure of human ATG5-ATG16L1(ATG5BD) complex (C2)
Descriptor: Autophagy protein 5, Autophagy-related protein 16-1
Authors:Archna, A, Scrima, A.
Deposit date:2017-04-19
Release date:2017-10-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Identification, biochemical characterization and crystallization of the central region of human ATG16L1.
Acta Crystallogr F Struct Biol Commun, 73, 2017
2HF8
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BU of 2hf8 by Molmil
Crystal structure of HypB from Methanocaldococcus jannaschii in the triphosphate form, in complex with zinc
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Probable hydrogenase nickel incorporation protein hypB, ...
Authors:Gasper, R, Scrima, A, Wittinghofer, A.
Deposit date:2006-06-23
Release date:2006-07-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural insights into HypB, a GTP-binding protein that regulates metal binding.
J.Biol.Chem., 281, 2006
5OJX
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BU of 5ojx by Molmil
Crystal structure of regulator protein 2 (PamR2) from the pamamycin biosynthetic gene cluster of Streptomyces alboniger
Descriptor: TetR family transcription regulator
Authors:Schmelz, S, Rebets, Y, Luzhetskyy, A, Scrima, A.
Deposit date:2017-07-24
Release date:2018-04-11
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Design, development and application of whole-cell based antibiotic-specific biosensor.
Metab. Eng., 47, 2018
2HF9
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BU of 2hf9 by Molmil
Crystal structure of HypB from Methanocaldococcus jannaschii in the triphosphate form
Descriptor: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Probable hydrogenase nickel incorporation protein hypB, ...
Authors:Gasper, R, Scrima, A, Wittinghofer, A.
Deposit date:2006-06-23
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into HypB, a GTP-binding protein that regulates metal binding.
J.Biol.Chem., 281, 2006
5NUV
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BU of 5nuv by Molmil
Structure of the WD40-domain of human ATG16L1
Descriptor: (R,R)-2,3-BUTANEDIOL, Autophagy-related protein 16-1
Authors:Bajagic, M, Scrima, A.
Deposit date:2017-05-02
Release date:2017-07-19
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of the WD40-domain of human ATG16L1.
Protein Sci., 26, 2017
5NTB
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BU of 5ntb by Molmil
Streptomyces papain inhibitor (SPI)
Descriptor: Papain inhibitor, SULFATE ION
Authors:Schmelz, S, Juettner, N.E, Fuchsbauer, H.L, Scrima, A.
Deposit date:2017-04-27
Release date:2018-03-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Illuminating structure and acyl donor sites of a physiological transglutaminase substrate from Streptomyces mobaraensis.
Protein Sci., 27, 2018
4BJT
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BU of 4bjt by Molmil
Crystal structure of the Rap1 C-terminal domain (Rap1-RCT) in complex with the Rap1 binding module of Rif1 (Rif1-RBM)
Descriptor: 1,2-ETHANEDIOL, DNA-BINDING PROTEIN RAP1, TELOMERE LENGTH REGULATOR PROTEIN RIF1
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-19
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJ6
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BU of 4bj6 by Molmil
Crystal structure Rif2 in complex with the C-terminal domain of Rap1 (Rap1-RCT)
Descriptor: DNA-BINDING PROTEIN RAP1, RAP1-INTERACTING FACTOR 2, SULFATE ION
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4A0K
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BU of 4a0k by Molmil
STRUCTURE OF DDB1-DDB2-CUL4A-RBX1 BOUND TO A 12 BP ABASIC SITE CONTAINING DNA-DUPLEX
Descriptor: 12 BP DNA, 12 BP THF CONTAINING DNA, CULLIN-4A, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (5.93 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4A0L
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BU of 4a0l by Molmil
Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex
Descriptor: 12 BP DNA DUPLEX, 12 BP THF CONTAINING DNA DUPLEX, CULLIN-4B, ...
Authors:Fischer, E.S, Scrima, A, Gut, H, Thoma, N.H.
Deposit date:2011-09-09
Release date:2011-12-14
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (7.4 Å)
Cite:The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
Cell(Cambridge,Mass.), 147, 2011
4BJ5
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BU of 4bj5 by Molmil
Crystal structure of Rif2 in complex with the C-terminal domain of Rap1 (Rap1-RCT)
Descriptor: DNA-BINDING PROTEIN RAP1, PROTEIN RIF2, SULFATE ION
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-16
Release date:2013-06-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJ1
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BU of 4bj1 by Molmil
Crystal structure of Saccharomyces cerevisiae RIF2
Descriptor: CHLORIDE ION, PROTEIN RIF2
Authors:Shi, T, Bunker, R.D, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-15
Release date:2013-06-19
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
4BJS
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BU of 4bjs by Molmil
Crystal structure of the Rif1 C-terminal domain (Rif1-CTD) from Saccharomyces cerevisiae
Descriptor: TELOMERE LENGTH REGULATOR PROTEIN RIF1
Authors:Bunker, R.D, Shi, T, Gut, H, Scrima, A, Thoma, N.H.
Deposit date:2013-04-19
Release date:2013-06-19
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Rif1 and Rif2 Shape Telomere Funcation and Architecture Through Multivalent RAP1 Interactions
Cell(Cambridge,Mass.), 153, 2013
5K7H
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BU of 5k7h by Molmil
Crystal structure of AibR in complex with the effector molecule isovaleryl coenzyme A
Descriptor: CHLORIDE ION, Isovaleryl-coenzyme A, NICKEL (II) ION, ...
Authors:Bock, T, Volz, C, Mueller, R, Blankenfeldt, W.
Deposit date:2016-05-26
Release date:2016-12-21
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Nucleic Acids Res., 45, 2017
7NBW
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BU of 7nbw by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with a pyridin agonist
Descriptor: Transcriptional regulator MvfR, ~{N}-[3-(4-fluorophenyl)prop-2-ynyl]-2-(trifluoromethyl)pyridin-4-amine
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2021-01-28
Release date:2021-10-06
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Divergent synthesis and biological evaluation of 2-(trifluoromethyl)pyridines as virulence-attenuating inverse agonists targeting PqsR.
Eur.J.Med.Chem., 226, 2021
6YIZ
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BU of 6yiz by Molmil
Crystal structure of PqsR (MvfR) ligand-binding domain in complex with triazolo-pyridine inverse agonist A
Descriptor: 7-oxidanylidene-8-[2-(4-sulfonaphthalen-1-yl)hydrazinyl]-8~{H}-naphthalene-1,3-disulfonic acid, MAGNESIUM ION, Transcriptional regulator MvfR, ...
Authors:Schmelz, S, Blankenfeldt, W.
Deposit date:2020-04-01
Release date:2021-04-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.163 Å)
Cite:A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Adv Sci, 8, 2021
2WBL
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BU of 2wbl by Molmil
Three-dimensional structure of a binary ROP-PRONE complex
Descriptor: RAC-LIKE GTP-BINDING PROTEIN ARAC2, RHO OF PLANTS GUANINE NUCLEOTIDE EXCHANGE FACTOR 8
Authors:Thomas, C, Fricke, I, Weyand, M, Berken, A.
Deposit date:2009-03-02
Release date:2009-04-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:3D Structure of a Binary Rop-Prone Complex: The Final Intermediate for a Complete Set of Molecular Snapshots of the Ropgef Reaction.
Biol.Chem., 390, 2009
5K7F
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BU of 5k7f by Molmil
Crystal structure of apo AibR
Descriptor: ACETATE ION, Transcriptional regulator, TetR family
Authors:Bock, T, Volz, C, Mueller, R, Blankenfeldt, W.
Deposit date:2016-05-26
Release date:2016-12-21
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Nucleic Acids Res., 45, 2017
4B0F
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BU of 4b0f by Molmil
Heptameric core complex structure of C4b-binding (C4BP) protein from human
Descriptor: C4B-BINDING PROTEIN ALPHA CHAIN, CHLORIDE ION
Authors:Schmelz, S, Hofmeyer, T, Kolmar, H, Heinz, D.W.
Deposit date:2012-07-02
Release date:2013-01-09
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Arranged Sevenfold: Structural Insights Into the C-Terminal Oligomerization Domain of Human C4B-Binding Protein.
J.Mol.Biol., 425, 2013
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