6YK0
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6YJZ
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6YK1
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6ZQH
| Yeast Uba1 in complex with ubiquitin | Descriptor: | BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ... | Authors: | Misra, M, Schindelin, H. | Deposit date: | 2020-07-09 | Release date: | 2020-11-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.032 Å) | Cite: | Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection. Chemistry, 27, 2021
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3TIW
| Crystal structure of p97N in complex with the C-terminus of gp78 | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase AMFR, Transitional endoplasmic reticulum ATPase | Authors: | Haenzelmann, P, Schindelin, H. | Deposit date: | 2011-08-22 | Release date: | 2011-09-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.802 Å) | Cite: | The Structural and Functional Basis of the p97/Valosin-containing Protein (VCP)-interacting Motif (VIM): MUTUALLY EXCLUSIVE BINDING OF COFACTORS TO THE N-TERMINAL DOMAIN OF p97. J.Biol.Chem., 286, 2011
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2PKO
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2Q5W
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2QIE
| Staphylococcus aureus molybdopterin synthase in complex with precursor Z | Descriptor: | (2R,4AR,5AR,11AR,12AS)-8-AMINO-2-HYDROXY-4A,5A,9,11,11A,12A-HEXAHYDRO[1,3,2]DIOXAPHOSPHININO[4',5':5,6]PYRANO[3,2-G]PTERIDINE-10,12(4H,6H)-DIONE 2-OXIDE, Molybdopterin synthase small subunit, Molybdopterin-converting factor subunit 2 | Authors: | Daniels, J.N, Schindelin, H. | Deposit date: | 2007-07-04 | Release date: | 2008-02-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a molybdopterin synthase-precursor Z complex: insight into its sulfur transfer mechanism and its role in molybdenum cofactor deficiency. Biochemistry, 47, 2008
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4BKM
| Crystal structure of the murine AUM (phosphoglycolate phosphatase) capping domain as a fusion protein with the catalytic core domain of murine chronophin (pyridoxal phosphate phosphatase) | Descriptor: | MAGNESIUM ION, NITRATE ION, PYRIDOXAL PHOSPHATE PHOSPHATASE, ... | Authors: | Knobloch, G, Seifried, A, Gohla, A, Schindelin, H. | Deposit date: | 2013-04-26 | Release date: | 2013-12-25 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Evolutionary and Structural Analyses of the Mammalian Haloacid Dehalogenase-Type Phosphatases Aum and Chronophin Provide Insight Into the Basis of Their Different Substrate Specificities. J.Biol.Chem., 289, 2014
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6ENT
| Structure of the rat RKIP variant delta143-146 | Descriptor: | CHLORIDE ION, Phosphatidylethanolamine-binding protein 1, ZINC ION | Authors: | Koelmel, W, Hirschbeck, M, Schindelin, H, Lorenz, K, Kisker, C. | Deposit date: | 2017-10-06 | Release date: | 2017-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.66 Å) | Cite: | Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6ENS
| Structure of mouse wild-type RKIP | Descriptor: | ACETATE ION, GLYCEROL, Phosphatidylethanolamine-binding protein 1 | Authors: | Hirschbeck, M, Koelmel, W, Schindelin, H, Lorenz, K, Kisker, C. | Deposit date: | 2017-10-06 | Release date: | 2017-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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6FGC
| Crystal structure of Gephyrin E domain in complex with Artesunate | Descriptor: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | Authors: | Kasaragod, V.B, Schindelin, H. | Deposit date: | 2018-01-10 | Release date: | 2019-01-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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6FGD
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3BOA
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3CMM
| Crystal Structure of the Uba1-Ubiquitin Complex | Descriptor: | PROLINE, Ubiquitin, Ubiquitin-activating enzyme E1 1 | Authors: | Lee, I, Schindelin, H. | Deposit date: | 2008-03-23 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes. Cell(Cambridge,Mass.), 134, 2008
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7PYV
| Crystal structure of human UBA6 in complex with the ubiquitin-like modifier FAT10 | Descriptor: | UBD, Ubiquitin-like modifier-activating enzyme 6,Ubiquitin-like modifier-activating enzyme 1,Ubiquitin-like modifier-activating enzyme 6 | Authors: | Li, S, Truongvan, N, Schindelin, H. | Deposit date: | 2021-10-11 | Release date: | 2022-08-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun, 13, 2022
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3ESW
| Complex of yeast PNGase with GlcNAc2-IAc. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase, UV excision repair protein RAD23, ... | Authors: | Zhao, G, Zhou, X, Lennarz, W.J, Schindelin, H. | Deposit date: | 2008-10-06 | Release date: | 2008-11-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural and mutational studies on the importance of oligosaccharide binding for the activity of yeast PNGase. Glycobiology, 19, 2009
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7PVN
| Crystal Structure of Human UBA6 in Complex with ATP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, CHLORIDE ION, ... | Authors: | Truongvan, N, Li, S, Schindelin, H. | Deposit date: | 2021-10-05 | Release date: | 2022-08-31 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | Structures of UBA6 explain its dual specificity for ubiquitin and FAT10. Nat Commun, 13, 2022
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7POE
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7PUX
| Structure of p97 N-D1(L198W) in complex with Fragment TROLL2 | Descriptor: | (1S)-2-amino-1-(4-bromophenyl)ethan-1-ol, ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bothe, S, Schindelin, H. | Deposit date: | 2021-10-01 | Release date: | 2022-12-14 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97 Commun Chem, 5, 2022
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3GAE
| Crystal Structure of PUL | Descriptor: | CHLORIDE ION, GLYCEROL, Protein DOA1 | Authors: | Zhao, G, Schindelin, H, Lennarz, W.J. | Deposit date: | 2009-02-17 | Release date: | 2009-12-15 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation Proc.Natl.Acad.Sci.USA, 106, 2009
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3QQ7
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3QQ8
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3R3M
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6ZHT
| Uba1-Ubc13 disulfide mediated complex | Descriptor: | CHLORIDE ION, GLYCEROL, Ubiquitin-activating enzyme E1 1, ... | Authors: | Schaefer, A, Misra, M, Schindelin, H. | Deposit date: | 2020-06-23 | Release date: | 2022-01-12 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
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