5LTG
 
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5LTD
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4V16
 | | KlHsv2 with loop 6CD replaced by a Gly-Ser linker | | 分子名称: | SVP1-LIKE PROTEIN 2 | | 著者 | Busse, R.A, Scacioc, A, Krick, R, Perez-Lara, A, Thumm, M, Kuhnel, K. | | 登録日 | 2014-09-25 | | 公開日 | 2015-04-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Characterization of Proppin-Phosphoinositide Binding and Role of Loop 6Cd in Proppin-Membrane Binding.
Biophys.J., 108, 2015
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8BLO
 | | Human Urea Transporter UT-A (N-Terminal Domain Model) | | 分子名称: | Lauryl Maltose Neopentyl Glycol, Urea transporter 2, di-heneicosanoyl phosphatidyl choline | | 著者 | Chi, G, Pike, A.C.W, Maclean, E.M, Mukhopadhyay, S.M.M, Bohstedt, T, Scacioc, A, Wang, D, McKinley, G, Fernandez-Cid, A, Arrowsmith, C.H, Bountra, C, Edwards, A, Burgess-Brown, N.A, van Putte, W, Duerr, K. | | 登録日 | 2022-11-10 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Sci Adv, 9, 2023
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8BLP
 | | Human Urea Transporter UT-B/UT1 in Complex with Inhibitor UTBinh-14 | | 分子名称: | 10-(4-ethylphenyl)sulfonyl-~{N}-(thiophen-2-ylmethyl)-5-thia-1,8,11,12-tetrazatricyclo[7.3.0.0^{2,6}]dodeca-2(6),3,7,9,11-pentaen-7-amine, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ... | | 著者 | Chi, G, Dietz, L, Pike, A.C.W, Maclean, E.M, Mukhopadhyay, S.M.M, Bohstedt, T, Wang, D, Scacioc, A, McKinley, G, Arrowsmith, C.H, Edwards, A, Bountra, C, Fernandez-Cid, A, Burgess-Brown, N.A, Duerr, K.L. | | 登録日 | 2022-11-10 | | 公開日 | 2023-10-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural characterization of human urea transporters UT-A and UT-B and their inhibition.
Sci Adv, 9, 2023
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6QD5
 | | X-ray Structure of the Human Urea Channel SLC14A1/UT1 | | 分子名称: | CHOLESTEROL HEMISUCCINATE, TETRAETHYLENE GLYCOL, Urea transporter 1, ... | | 著者 | Dietz, L, Chi, G, Pike, A.C.W, Moreau, C, Man, H, Snee, M, Scacioc, A, Shrestha, L, Mukhopadhyay, S.M.M, Mckinley, G, Ellis, K, Kliszcak, M, Chalk, R, Borkowska, O, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Durr, K.L, Structural Genomics Consortium (SGC) | | 登録日 | 2018-12-31 | | 公開日 | 2019-01-09 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | | 主引用文献 | X-ray Structure of the Human Urea Channel SLC14A1/UT1
To Be Published
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4AV9
 | | Kluyveromyces lactis Hsv2 | | 分子名称: | SULFATE ION, SVP1-LIKE PROTEIN 2 | | 著者 | Krick, R, Busse, R.A, Scacioc, A, Stephan, M, Janshoff, A, Thumm, M, Kuhnel, K. | | 登録日 | 2012-05-24 | | 公開日 | 2012-06-13 | | 最終更新日 | 2012-08-15 | | 実験手法 | X-RAY DIFFRACTION (3.001 Å) | | 主引用文献 | Structural and Functional Characterization of the Two Phosphoinositide Binding Sites of Proppins, a Beta-Propeller Protein Family.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4AV8
 | | Kluyveromyces lactis Hsv2 complete loop 6CD | | 分子名称: | SVP1-LIKE PROTEIN 2 | | 著者 | Krick, R, Busse, R.A, Scacioc, A, Stephan, M, Janshoff, A, Thumm, M, Kuhnel, K. | | 登録日 | 2012-05-24 | | 公開日 | 2012-06-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structural and Functional Characterization of the Two Phosphoinositide Binding Sites of Proppins, a Beta-Propeller Protein Family.
Proc.Natl.Acad.Sci.USA, 109, 2012
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6YMQ
 | | TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Single-chain variable 4, ... | | 著者 | Szykowska, A, Preger, C, Scacioc, A, Mukhopadhyay, S.M.M, McKinley, G, Graslund, S, Wigren, E, Persson, H, von Delft, F, Arrowsmith, C.H, Edwards, A, Bountra, C, Di Daniel, E, Davis, J.B, Burgess-Brown, N, Bullock, A. | | 登録日 | 2020-04-09 | | 公開日 | 2021-02-17 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Selection and structural characterization of anti-TREM2 scFvs that reduce levels of shed ectodomain.
Structure, 29, 2021
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6XY7
 | | Human SHIP1 with magnesium and phosphate bound to the active site | | 分子名称: | DIMETHYL SULFOXIDE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Bradshaw, W.J, Scacioc, A, Fernandez-Cid, A, Mckinley, G, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O. | | 登録日 | 2020-01-29 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.086 Å) | | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
Structure, 2024
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8PDG
 | | The phosphatase and C2 domains of SHIP1 with covalent Z2738285202 | | 分子名称: | DIMETHYL SULFOXIDE, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, ~{N}-(8-chloranylquinolin-2-yl)propanamide | | 著者 | Bradshaw, W.J, Moreira, T, Scacioc, A, Bountra, C, Chalk, R, von Delft, F, Brennan, P.E, Gileadi, O. | | 登録日 | 2023-06-12 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-04-17 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Regulation of inositol 5-phosphatase activity by the C2 domain of SHIP1 and SHIP2.
Structure, 32, 2024
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