6XY7

Human SHIP1 with magnesium and phosphate bound to the active site

This is a large structure.

Summary for 6XY7

DescriptorPhosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1, MAGNESIUM ION, PHOSPHATE ION, ... (6 entities in total)
Functional Keywordsphosphatidylinositol, phosphate, phosphatase, alzheimer's disease, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight53381.42
Authors
Primary citation
Bradshaw, W.J.,Scacioc, A.,Fernandez-Cid, A.,Mckinley, G.,Burgess-Brown, N.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Gileadi, O.
Human SHIP1 with magnesium and phosphate bound to the active site
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.086 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.16040 0.5% 5.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload