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6XY7

Human SHIP1 with magnesium and phosphate bound to the active site

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(AAA)
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1polymer46352877.61UniProt (Q92835)
Pfam (PF22669)
Homo sapiens (Human)Inositol polyphosphate-5-phosphatase of 145 kDa,SIP-145,SH2 domain-containing inositol 5'-phosphatase 1,SHIP-1,p150Ship,hp51CN
2B
(AAA)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
3C
(AAA)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
4D, E, F
(AAA)
DIMETHYL SULFOXIDEnon-polymer78.13Chemie (DMS)
5G
(AAA)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
6H
(AAA)
waterwater18.0489Chemie (HOH)
Sequence modifications
AAA: 396 - 856 (UniProt: Q92835)
PDBExternal DatabaseDetails
Ser 394-expression tag
Met 395-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight52877.6
Non-Polymers*Number of molecules6
Total formula weight503.8
All*Total formula weight53381.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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