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1ZZI
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BU of 1zzi by Molmil
Crystal Structure Analysis of the third KH domain of hnRNP K in complex with ssDNA
Descriptor: 5'-D(*CP*TP*CP*CP*CP*C)-3', Heterogeneous nuclear ribonucleoprotein K
Authors:Backe, P.H, Messias, A.C, Ravelli, R.B, Sattler, M, Cusack, S.
Deposit date:2005-06-14
Release date:2005-08-09
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-Ray Crystallographic and NMR Studies of the Third KH Domain of hnRNP K in Complex with Single-Stranded Nucleic Acids
STRUCTURE, 13, 2005
2B9Z
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BU of 2b9z by Molmil
Solution structure of FHV B2, a viral suppressor of RNAi
Descriptor: B2 protein
Authors:Lingel, A, Simon, B, Izaurralde, E, Sattler, M.
Deposit date:2005-10-13
Release date:2005-11-29
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition.
Embo Rep., 6, 2005
2C5Z
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BU of 2c5z by Molmil
Structure and CTD binding of the Set2 SRI domain
Descriptor: SET DOMAIN PROTEIN 2
Authors:Vojnic, E, Simon, B, Strahl, B.D, Sattler, M, Cramer, P.
Deposit date:2005-11-03
Release date:2005-11-14
Last modified:2018-05-09
Method:SOLUTION NMR
Cite:Structure and carboxyl-terminal domain (CTD) binding of the Set2 SRI domain that couples histone H3 Lys36 methylation to transcription.
J. Biol. Chem., 281, 2006
5JU7
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BU of 5ju7 by Molmil
DNA BINDING DOMAIN OF E.COLI CADC
Descriptor: Transcriptional activator CadC, ZINC ION
Authors:Janowski, R, Schlundt, A, Sattler, M, Niessing, D.
Deposit date:2016-05-10
Release date:2017-04-26
Last modified:2017-05-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
Sci Rep, 7, 2017
6ELD
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BU of 6eld by Molmil
Crystal structure of TIA-1 RRM1 in complex with U1C
Descriptor: Nucleolysin TIA-1 isoform p40,U1 small nuclear ribonucleoprotein C
Authors:Jagtap, P.K.A, Sattler, M.
Deposit date:2017-09-28
Release date:2018-10-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.485 Å)
Cite:Crystal structure of TIA-1 RRM1 in complex with U1C
To Be Published
5LSO
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BU of 5lso by Molmil
Crystal structure of SPF45 UHM domain with cyclic peptide inhibitor
Descriptor: LYS-SER-ARG-TRP-ASP-GLU, Splicing factor 45
Authors:Jagtap, P.K.A, Garg, D, Sattler, M.
Deposit date:2016-09-05
Release date:2016-10-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.22 Å)
Cite:Rational Design of Cyclic Peptide Inhibitors of U2AF Homology Motif (UHM) Domains To Modulate Pre-mRNA Splicing.
J. Med. Chem., 59, 2016
6F8G
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BU of 6f8g by Molmil
Co-crystal structure of SPOP MATH domain and hamster Pdx1 fragment
Descriptor: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2017-12-13
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
5MFY
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BU of 5mfy by Molmil
RBM5 OCRE domain
Descriptor: RNA-binding protein 5
Authors:Warner, L.R, Mourao, A, Soni, K, Sattler, M.
Deposit date:2016-11-19
Release date:2016-12-07
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
Elife, 5, 2016
6SLO
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BU of 6slo by Molmil
Crystal structure of PUF60 UHM domain in complex with 7,8 dimethoxyperphenazine
Descriptor: 2-[4-[3-(8-chloranyl-2,3-dimethoxy-phenothiazin-10-yl)propyl]piperazin-1-yl]ethanol, MAGNESIUM ION, Thioredoxin,Poly(U)-binding-splicing factor PUF60
Authors:Jagtap, P.K.A, Kubelka, T, Bach, T, Sattler, M.
Deposit date:2019-08-20
Release date:2020-09-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Identification of phenothiazine derivatives as UHM-binding inhibitors of early spliceosome assembly.
Nat Commun, 11, 2020
6F8F
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BU of 6f8f by Molmil
Co-crystal structure of SPOP MATH domain and human Pdx1 fragment
Descriptor: Pancreas/duodenum homeobox protein 1, Speckle-type POZ protein
Authors:Ostertag, M.S, Popowicz, G.M, Sattler, M.
Deposit date:2017-12-13
Release date:2018-11-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Structure of the SPOP-Pdx1 Interface Reveals Insights into the Phosphorylation-Dependent Binding Regulation.
Structure, 27, 2019
5MF9
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BU of 5mf9 by Molmil
Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide.
Descriptor: RNA-binding protein 5, Survival motor neuron protein
Authors:Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J.
Deposit date:2016-11-17
Release date:2016-12-07
Last modified:2018-01-31
Method:SOLUTION NMR
Cite:Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
6TR0
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BU of 6tr0 by Molmil
Solution structure of U2AF2 RRM1,2
Descriptor: Splicing factor U2AF 65 kDa subunit
Authors:Kang, H.-S, Sattler, M.
Deposit date:2019-12-17
Release date:2020-05-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
6YI4
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BU of 6yi4 by Molmil
Structure of IMP-13 metallo-beta-lactamase complexed with citrate anion
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, BETA-MERCAPTOETHANOL, ...
Authors:Zak, K.M, Zhou, R.X, Softley, C.A, Bostock, M.J, Sattler, M, Popowicz, G.M.
Deposit date:2020-03-31
Release date:2020-04-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of IMP-13 metallo-beta-lactamase complexed with citrate anion
Not published
4B9W
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BU of 4b9w by Molmil
Structure of extended Tudor domain TD3 from mouse TDRD1 in complex with MILI peptide containing dimethylarginine 45.
Descriptor: GLYCEROL, PIWI-LIKE PROTEIN 2, TUDOR DOMAIN-CONTAINING PROTEIN 1
Authors:Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
Deposit date:2012-09-08
Release date:2012-10-17
Last modified:2019-04-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The multiple Tudor domain-containing protein TDRD1 is a molecular scaffold for mouse Piwi proteins and piRNA biogenesis factors.
Rna, 18, 2012
6ZFW
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BU of 6zfw by Molmil
X-ray structure of the soluble N-terminal domain of T. cruzi PEX-14
Descriptor: ACETATE ION, BETA-MERCAPTOETHANOL, GLYCEROL, ...
Authors:Softley, C.A, Ostertag, M.O, Sattler, M, Popowicz, G.P.
Deposit date:2020-06-18
Release date:2020-12-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Deep learning model predicts water interaction sites on the surface of proteins using limited-resolution data.
Chem.Commun.(Camb.), 56, 2020
4B9X
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BU of 4b9x by Molmil
Structure of extended Tudor domain TD3 from mouse TDRD1
Descriptor: TUDOR DOMAIN-CONTAINING PROTEIN 1
Authors:Mathioudakis, N, Palencia, A, Kadlec, J, Round, A, Tripsianes, K, Sattler, M, Pillai, R.S, Cusack, S.
Deposit date:2012-09-08
Release date:2012-10-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Multiple Tudor Domain-Containing Protein Tdrd1 is a Molecular Scaffold for Mouse Piwi Proteins and Pirna Biogenesis Factors.
RNA, 18, 2012
7AAF
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BU of 7aaf by Molmil
Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
Descriptor: U2 snRNP auxiliary factor large subunit
Authors:Kawale, A.A, Kang, H.S, Sattler, M.
Deposit date:2020-09-04
Release date:2021-10-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2
To Be Published
2W4S
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BU of 2w4s by Molmil
novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution
Descriptor: ANKYRIN-REPEAT PROTEIN
Authors:Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S.
Deposit date:2008-12-02
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
2WAC
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BU of 2wac by Molmil
Extended Tudor domain of Drosophila Melanogaster Tudor-SN (p100)
Descriptor: CG7008-PA
Authors:Friberg, A, Corsini, L, Sattler, M.
Deposit date:2009-02-04
Release date:2009-03-03
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and Ligand Binding of the Extended Tudor Domain of D. Melanogaster Tudor-Sn
J.Mol.Biol., 387, 2009
2XK0
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BU of 2xk0 by Molmil
Solution structure of the Tudor domain from Drosophila Polycomblike (Pcl)
Descriptor: POLYCOMB PROTEIN PCL
Authors:Friberg, A, Oddone, A, Klymenko, T, Mueller, J, Sattler, M.
Deposit date:2010-07-07
Release date:2010-08-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structure of an Atypical Tudor Domain in the Drosophila Polycomblike Protein
Protein Sci., 19, 2010
2XC7
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BU of 2xc7 by Molmil
Solution Structure of PHAX-RBD in complex with ssRNA
Descriptor: 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN
Authors:Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M.
Deposit date:2010-04-18
Release date:2010-04-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
2XL1
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BU of 2xl1 by Molmil
Structural basis of translational stalling by human cytomegalovirus (hCMV) and fungal arginine attenuator peptide (AAP)
Descriptor: ARGININE ATTENUATOR PEPTIDE
Authors:Meyer, N.H, Sattler, M.
Deposit date:2010-07-15
Release date:2010-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide.
Mol.Cell, 40, 2010
2YH1
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BU of 2yh1 by Molmil
Model of human U2AF65 tandem RRM1 and RRM2 domains with eight-site uridine binding
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP)-3', SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
2YH0
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BU of 2yh0 by Molmil
Solution structure of the closed conformation of human U2AF65 tandem RRM1 and RRM2 domains
Descriptor: SPLICING FACTOR U2AF 65 KDA SUBUNIT
Authors:Mackereth, C.D, Madl, T, Simon, B, Zanier, K, Gasch, A, Sattler, M.
Deposit date:2011-04-26
Release date:2011-07-20
Last modified:2019-09-25
Method:SOLUTION NMR
Cite:Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af
Nature, 475, 2011
5IL7
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BU of 5il7 by Molmil
Leucine rich repeat domain of the Chlorobium tepidum Roco protein
Descriptor: Rab family protein
Authors:Gotthardt, K, Wittinghofer, A.
Deposit date:2016-03-04
Release date:2016-03-16
Last modified:2017-01-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts.
Proc.Natl.Acad.Sci.USA, 113, 2016

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