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2DOS
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BU of 2dos by Molmil
Structural basis for the recognition of Lys48-linked polyubiquitin chain by the Josephin domain of ataxin-3, a putative deubiquitinating enzyme
Descriptor: Ataxin-3
Authors:Sumiyoshi, A.
Deposit date:2006-05-03
Release date:2007-05-22
Last modified:2014-12-31
Method:SOLUTION NMR
Cite:Mode of substrate recognition by the Josephin domain of ataxin-3, which has an endo-type deubiquitinase activity.
Febs Lett., 588, 2014
1GDV
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BU of 1gdv by Molmil
CRYSTAL STRUCTURE OF CYTOCHROME C6 FROM RED ALGA PORPHYRA YEZOENSIS AT 1.57 A RESOLUTION
Descriptor: CYTOCHROME C6, HEME C
Authors:Yamada, S, Park, S.-Y, Shimizu, H, Shiro, Y, Oku, T.
Deposit date:2000-10-06
Release date:2001-04-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structure of cytochrome c6 from the red alga Porphyra yezoensis at 1. 57 A resolution.
Acta Crystallogr.,Sect.D, 56, 2000
8TQG
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BU of 8tqg by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor X20419
Descriptor: N-benzyl-2-{4-[4-(4,5-dimethoxy-1H-indole-2-carbonyl)piperazine-1-carbonyl]piperidin-1-yl}-6-methylpyrimidine-4-carboxamide, Polyketide synthase Pks13, SULFATE ION
Authors:Krieger, I.V, Sacchettini, J.C.
Deposit date:2023-08-07
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
Acs Infect Dis., 2024
8TQV
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BU of 8tqv by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor X20403
Descriptor: 4-(2-{(4M)-4-[(6M)-6-(2,5-dimethoxyphenyl)pyridin-3-yl]-1H-1,2,3-triazol-1-yl}ethyl)-N-{[1-(methoxymethyl)cyclopropyl]methyl}-N-methylbenzamide, Polyketide synthase Pks13, SULFATE ION
Authors:Krieger, I.V, Sacchettini, J.C.
Deposit date:2023-08-08
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
Acs Infect Dis., 2024
8TR4
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BU of 8tr4 by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor X20404
Descriptor: 4-(2-{(4M)-4-[(6M)-6-(2,5-dimethoxyphenyl)pyridin-3-yl]-1H-1,2,3-triazol-1-yl}ethyl)-N,N-dimethylbenzamide, Polyketide synthase Pks13, SULFATE ION
Authors:Krieger, I.V, Sacchettini, J.C.
Deposit date:2023-08-09
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
Acs Infect Dis., 2024
8TRY
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BU of 8try by Molmil
Crystal Structure of Mtb Pks13 Thioesterase domain in complex with inhibitor X20348
Descriptor: N-{(2S,3S)-4-[3-(dimethylamino)-1,2,4-oxadiazol-5-yl]-3-hydroxy-1-phenylbutan-2-yl}-4-(2-methylbutan-2-yl)benzene-1-sulfonamide, Polyketide synthase Pks13, SULFATE ION
Authors:Krieger, I.V, Sacchettini, J.C.
Deposit date:2023-08-10
Release date:2024-04-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Inhibitors of the Thioesterase Activity of Mycobacterium tuberculosis Pks13 Discovered Using DNA-Encoded Chemical Library Screening.
Acs Infect Dis., 2024
7E55
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BU of 7e55 by Molmil
Cryo-EM structure of alpha 7 homo-tetradecamer
Descriptor: Proteasome subunit alpha type-3
Authors:Song, C, Murata, K.
Deposit date:2021-02-17
Release date:2021-05-05
Last modified:2021-05-19
Method:ELECTRON MICROSCOPY (5.9 Å)
Cite:Structural Fluctuations of the Human Proteasome alpha 7 Homo-Tetradecamer Double Ring Imply the Proteasomal alpha-Ring Assembly Mechanism.
Int J Mol Sci, 22, 2021
5TQU
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BU of 5tqu by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor
Descriptor: 2-[2-[[3-(1~{H}-benzimidazol-2-ylamino)propylamino]methyl]-4,6-bis(chloranyl)indol-1-yl]ethanol, GLYCEROL, METHIONINE, ...
Authors:Barros-Alvarez, X, Hol, W.G.J.
Deposit date:2016-10-24
Release date:2017-04-12
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:From Cells to Mice to Target: Characterization of NEU-1053 (SB-443342) and Its Analogues for Treatment of Human African Trypanosomiasis.
ACS Infect Dis, 3, 2017
2ZBO
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BU of 2zbo by Molmil
Crystal structure of low-redox-potential cytochrom c6 from brown alga Hizikia fusiformis at 1.6 A resolution
Descriptor: Cytochrome c6, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Akazaki, H, Kawai, F, Chida, H, Matsumoto, Y, Sirasaki, I, Nakade, H, Hirayama, M, Hosikawa, K, Suruga, K, Satoh, T, Yamada, S, Unzai, S, Hakamata, W, Nishio, T, Park, S.-Y, Oku, T.
Deposit date:2007-10-26
Release date:2008-09-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cloning, expression and purification of cytochrome c(6) from the brown alga Hizikia fusiformis and complete X-ray diffraction analysis of the structure
ACTA CRYSTALLOGR.,SECT.F, 64, 2008
5VND
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BU of 5vnd by Molmil
Crystal structure of FGFR1-Y563C (FGFR4 surrogate) covalently bound to H3B-6527
Descriptor: 1,2-ETHANEDIOL, Fibroblast growth factor receptor 1, N-{2-[(6-{[(2,6-dichloro-3,5-dimethoxyphenyl)carbamoyl](methyl)amino}pyrimidin-4-yl)amino]-5-(4-ethylpiperazin-1-yl)phenyl}propanamide, ...
Authors:Tsai, J.H.C, Reynolds, D, Fekkes, P, Smith, P, Larsen, N.A.
Deposit date:2017-04-30
Release date:2017-05-24
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:H3B-6527 Is a Potent and Selective Inhibitor of FGFR4 in FGF19-Driven Hepatocellular Carcinoma.
Cancer Res., 77, 2017
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