6DTX
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![BU of 6dtx by Molmil](/molmil-images/mine/6dtx) | Wildtype HIV-1 Reverse Transcriptase in complex with JLJ 578 | Descriptor: | 8-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-6-fluoroindolizine-2-carbonitrile, GLYCEROL, Reverse transcriptase/ribonuclease H, ... | Authors: | Sasaki, T, Gannam, Z.T.K, Anderson, K.S, Jorgensen, W.L, Lee, W. | Deposit date: | 2018-06-18 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.327 Å) | Cite: | Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 29, 2019
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6DTW
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![BU of 6dtw by Molmil](/molmil-images/mine/6dtw) | HIV-1 Reverse Transcriptase Y181C Mutant in complex with JLJ 578 | Descriptor: | 8-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-6-fluoroindolizine-2-carbonitrile, MAGNESIUM ION, Reverse transcriptase/ribonuclease H, ... | Authors: | Sasaki, T, Gannam, Z.T.K, Anderson, K.S, Jorgensen, W.L, Lee, W. | Deposit date: | 2018-06-18 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.742 Å) | Cite: | Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 29, 2019
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2C5D
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![BU of 2c5d by Molmil](/molmil-images/mine/2c5d) | Structure of a minimal Gas6-Axl complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN 6 PRECURSOR, ... | Authors: | Sasaki, T, Knyazev, P.G, Clout, N.J, Cheburkin, Y, Goehring, W, Ullrich, A, Timpl, R, Hohenester, E. | Deposit date: | 2005-10-26 | Release date: | 2005-12-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural Basis for Gas6-Axl Signalling. Embo J., 25, 2006
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1H30
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![BU of 1h30 by Molmil](/molmil-images/mine/1h30) | C-terminal LG domain pair of human Gas6 | Descriptor: | CALCIUM ION, GROWTH-ARREST-SPECIFIC PROTEIN, SULFATE ION | Authors: | Sasaki, T, Knyazev, P.G, Cheburkin, Y, Gohring, W, Tisi, D, Ullrich, A, Timpl, R, Hohenester, E. | Deposit date: | 2002-08-21 | Release date: | 2003-01-30 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structure of a Carboxy-Terminal Fragment of Growth-Arrest-Specific Protein Gas6: Receptor Tyrosine Kinase Activation by Laminin G-Like Domains J.Biol.Chem., 277, 2002
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1WOZ
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![BU of 1woz by Molmil](/molmil-images/mine/1woz) | Crystal structure of uncharacterized protein ST1454 from Sulfolobus tokodaii | Descriptor: | (20S)-2,5,8,11,14,17-HEXAMETHYL-3,6,9,12,15,18-HEXAOXAHENICOSANE-1,20-DIOL, 177aa long conserved hypothetical protein (ST1454) | Authors: | Sasaki, T, Tanaka, Y, Yasutake, Y, Yao, M, Tanaka, I, Tsumoto, K, Kumagai, I. | Deposit date: | 2004-08-27 | Release date: | 2005-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of the uncharacterized protein ST1454 from Sulfolobus tokodaii. To be Published
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1NUB
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![BU of 1nub by Molmil](/molmil-images/mine/1nub) | HELIX C DELETION MUTANT OF BM-40 FS-EC DOMAIN PAIR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BASEMENT MEMBRANE PROTEIN BM-40, CALCIUM ION | Authors: | Hohenester, E, Sasaki, T, Timpl, R. | Deposit date: | 1997-12-05 | Release date: | 1998-12-30 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure and mapping by site-directed mutagenesis of the collagen-binding epitope of an activated form of BM-40/SPARC/osteonectin. EMBO J., 17, 1998
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1DY2
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![BU of 1dy2 by Molmil](/molmil-images/mine/1dy2) | Murine collagen alpha1(XV), endostatin domain | Descriptor: | COLLAGEN ALPHA1(XV) CHAIN, SULFATE ION | Authors: | Tisi, D, Hohenester, E, Sasaki, T, Timpl, R. | Deposit date: | 2000-01-21 | Release date: | 2001-01-21 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Endostatin Derived from Collagens Xv and Xviii Differ in Structural and Binding Properties, Tissue Distribution and Anti-Angiogenic Activity J.Mol.Biol., 301, 2000
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1WVT
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![BU of 1wvt by Molmil](/molmil-images/mine/1wvt) | Crystal structure of uncharacterized protein ST2180 from Sulfolobus tokodaii | Descriptor: | hypothetical protein ST2180 | Authors: | Sasaki, T, Tanaka, Y, Yasutake, Y, Tsumoto, K, Tanaka, I, Kumagai, I. | Deposit date: | 2004-12-27 | Release date: | 2006-01-03 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Molecular properties of two proteins homologous to PduO-type ATP:cob(I)alamin adenosyltransferase from Sulfolobus tokodaii Proteins, 68, 2007
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1BY2
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![BU of 1by2 by Molmil](/molmil-images/mine/1by2) | |
4J70
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![BU of 4j70 by Molmil](/molmil-images/mine/4j70) | Yeast 20S proteasome in complex with the belactosin derivative 3e | Descriptor: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | Authors: | Kawamura, S, Unno, Y, List, A, Tanaka, M, Sasaki, T, Arisawa, M, Asai, A, Groll, M, Shuto, S. | Deposit date: | 2013-02-12 | Release date: | 2013-04-17 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Potent Proteasome Inhibitors Derived from the Unnatural cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action. J.Med.Chem., 56, 2013
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1OKQ
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![BU of 1okq by Molmil](/molmil-images/mine/1okq) | LAMININ ALPHA 2 CHAIN LG4-5 DOMAIN PAIR, CA1 SITE MUTANT | Descriptor: | CALCIUM ION, LAMININ ALPHA 2 CHAIN | Authors: | Wizemann, H, Garbe, J.H.O, Friedrich, M.V.K, Timpl, R, Sasaki, T, Hohenester, E. | Deposit date: | 2003-07-28 | Release date: | 2003-09-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Distinct Requirements for Heparin and Alpha-Dystroglycan Binding Revealed by Structure-Based Mutagenesis of the Laminin Alpha2 Lg4-Lg5 Domain Pair J.Mol.Biol., 332, 2003
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2V53
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![BU of 2v53 by Molmil](/molmil-images/mine/2v53) | Crystal structure of a SPARC-collagen complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, COLLAGEN ALPHA-1(III) CHAIN, ... | Authors: | Hohenester, E, Sasaki, T, Giudici, C, Farndale, R.W, Bachinger, H.P. | Deposit date: | 2008-10-01 | Release date: | 2008-11-25 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis of Sequence-Specific Collagen Recognition by Sparc. Proc.Natl.Acad.Sci.USA, 105, 2008
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1DY0
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![BU of 1dy0 by Molmil](/molmil-images/mine/1dy0) | |
1DY1
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![BU of 1dy1 by Molmil](/molmil-images/mine/1dy1) | |
1V4Q
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![BU of 1v4q by Molmil](/molmil-images/mine/1v4q) | |
1V5A
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![BU of 1v5a by Molmil](/molmil-images/mine/1v5a) | |
1FU3
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![BU of 1fu3 by Molmil](/molmil-images/mine/1fu3) | |
1F3K
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![BU of 1f3k by Molmil](/molmil-images/mine/1f3k) | THREE-DIMENSIONAL SOLUTION STRUCTURE OF OMEGA-CONOTOXIN TXVII, AN L-TYPE CALCIUM CHANNEL BLOCKER | Descriptor: | OMEGA-CONOTOXIN TXVII | Authors: | Kobayashi, K, Sasaki, T, Sato, K, Kohno, T. | Deposit date: | 2000-06-05 | Release date: | 2000-12-13 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of omega-conotoxin TxVII, an L-type calcium channel blocker. Biochemistry, 39, 2000
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1WSC
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![BU of 1wsc by Molmil](/molmil-images/mine/1wsc) | Crystal structure of ST0229, function unknown protein from Sulfolobus tokodaii | Descriptor: | Hypothetical protein ST0229 | Authors: | Murayama, T, Tanaka, Y, Sasaki, T, Yasutake, Y, Yao, M, Tsumoto, K, Tanaka, I, Kumagai, I. | Deposit date: | 2004-11-05 | Release date: | 2005-11-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Crystal structure of ST0229, function unknown protein from Sulfolobus tokodaii To be Published
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1KOE
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![BU of 1koe by Molmil](/molmil-images/mine/1koe) | ENDOSTATIN | Descriptor: | ENDOSTATIN | Authors: | Hohenester, E, Sasaki, T, Olsen, B.R, Timpl, R. | Deposit date: | 1998-01-22 | Release date: | 1999-02-16 | Last modified: | 2021-03-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution. EMBO J., 17, 1998
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1HP9
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![BU of 1hp9 by Molmil](/molmil-images/mine/1hp9) | kappa-Hefutoxins: a novel Class of Potassium Channel Toxins from Scorpion venom | Descriptor: | kappa-hefutoxin 1 | Authors: | Srinivasan, K.N, Sivaraja, V, Huys, I, Sasaki, T, Cheng, B, Kumar, T.K.S, Sato, K, Tytgat, J, Yu, C, Brian Chia, C.S, Ranganathan, S, Bowie, J.H, Kini, R.M, Gopalakrishnakone, P. | Deposit date: | 2000-12-12 | Release date: | 2002-08-28 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity. J.Biol.Chem., 277, 2002
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2DGD
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![BU of 2dgd by Molmil](/molmil-images/mine/2dgd) | Crystal structure of ST0656, a function unknown protein from Sulfolobus tokodaii | Descriptor: | 223aa long hypothetical arylmalonate decarboxylase, GLYCEROL | Authors: | Tanaka, Y, Sasaki, T, Tanabe, E, Yao, M, Tanaka, I, Kumagai, I, Tsumoto, K. | Deposit date: | 2006-03-10 | Release date: | 2007-03-13 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of ST0656, a function unknown protein from Sulfolobus tokodaii To be Published
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3AE7
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![BU of 3ae7 by Molmil](/molmil-images/mine/3ae7) | Crystal structure of porcine heart mitochondrial complex II bound with 2-Iodo-N-(3-isopropoxy-phenyl)-benzamide | Descriptor: | 2-iodo-N-[3-(1-methylethoxy)phenyl]benzamide, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K. | Deposit date: | 2010-02-04 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.62 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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3AE9
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![BU of 3ae9 by Molmil](/molmil-images/mine/3ae9) | Crystal structure of porcine heart mitochondrial complex II bound with N-(3-Pentafluorophenyloxy-phenyl)-2-trifluoromethyl-benzamide | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K. | Deposit date: | 2010-02-04 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.31 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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3ABV
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![BU of 3abv by Molmil](/molmil-images/mine/3abv) | Crystal structure of porcine heart mitochondrial complex II bound with N-Biphenyl-3-yl-2-trifluoromethyl-benzamide | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Harada, S, Sasaki, T, Shindo, M, Kido, Y, Inaoka, D.K, Omori, J, Osanai, A, Sakamoto, K, Mao, J, Matsuoka, S, Inoue, M, Honma, T, Tanaka, A, Kita, K. | Deposit date: | 2009-12-22 | Release date: | 2011-02-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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