6WYJ
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![BU of 6wyj by Molmil](/molmil-images/mine/6wyj) | Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate state | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog | Authors: | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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6WYL
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![BU of 6wyl by Molmil](/molmil-images/mine/6wyl) | Cryo-EM structure of GltPh L152C-G351C mutant in the intermediate outward-facing state. | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog | Authors: | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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6WYK
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![BU of 6wyk by Molmil](/molmil-images/mine/6wyk) | Cryo-EM structure of the GltPh L152C-G321C mutant in the intermediate chloride conducting state. | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog | Authors: | Font, J, Chen, I, Sobti, M, Stewart, A.G, Ryan, R.M. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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6BAT
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![BU of 6bat by Molmil](/molmil-images/mine/6bat) | Crystal Structure of Wild-Type GltPh in complex with L-aspartate | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | Deposit date: | 2017-10-15 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nat Commun, 9, 2018
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6BAV
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![BU of 6bav by Molmil](/molmil-images/mine/6bav) | Crystal Structure of GltPh R397C in complex with S-Benzyl-L-Cysteine | Descriptor: | BENZYLCYSTEINE, Glutamate transporter homolog, SODIUM ION | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | Deposit date: | 2017-10-16 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nat Commun, 9, 2018
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6BMI
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![BU of 6bmi by Molmil](/molmil-images/mine/6bmi) | Crystal Structure of GltPh R397C in complex with L-Serine | Descriptor: | Glutamate transporter homolog, SERINE, SODIUM ION | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | Deposit date: | 2017-11-14 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nat Commun, 9, 2018
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6BAU
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![BU of 6bau by Molmil](/molmil-images/mine/6bau) | Crystal Structure of GltPh R397C in complex with L-Cysteine | Descriptor: | CYSTEINE, Glutamate transporter homolog, SODIUM ION | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | Deposit date: | 2017-10-15 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nat Commun, 9, 2018
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6WZB
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![BU of 6wzb by Molmil](/molmil-images/mine/6wzb) | Crystal structure of the GltPh V216C-G388C mutant cross-linked with divalent mercury | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, MERCURY (II) ION, ... | Authors: | Chen, I, Font, J, Ryan, R. | Deposit date: | 2020-05-13 | Release date: | 2021-02-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Glutamate transporters have a chloride channel with two hydrophobic gates. Nature, 591, 2021
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6X01
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![BU of 6x01 by Molmil](/molmil-images/mine/6x01) | |
2NWW
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![BU of 2nww by Molmil](/molmil-images/mine/2nww) | Crystal structure of GltPh in complex with TBOA | Descriptor: | (3S)-3-(BENZYLOXY)-L-ASPARTIC ACID, 425aa long hypothetical proton glutamate symport protein | Authors: | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | Deposit date: | 2006-11-16 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature, 445, 2007
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2NWX
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![BU of 2nwx by Molmil](/molmil-images/mine/2nwx) | Crystal structure of GltPh in complex with L-aspartate and sodium ions | Descriptor: | 425aa long hypothetical proton glutamate symport protein, ASPARTIC ACID, PALMITIC ACID, ... | Authors: | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | Deposit date: | 2006-11-16 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature, 445, 2007
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2NWL
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![BU of 2nwl by Molmil](/molmil-images/mine/2nwl) | Crystal structure of GltPh in complex with L-Asp | Descriptor: | ASPARTIC ACID, PALMITIC ACID, glutamate symport protein | Authors: | Gouaux, E, Boudker, O, Ryan, R, Yernool, D, Shimamoto, K. | Deposit date: | 2006-11-15 | Release date: | 2007-02-27 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter. Nature, 445, 2007
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7LQK
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![BU of 7lqk by Molmil](/molmil-images/mine/7lqk) | Crystal structure of the R375A mutant of LeuT | Descriptor: | ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Font, J, Aguilar, J, Galli, A, Ryan, R. | Deposit date: | 2021-02-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia. Elife, 10, 2021
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7LQJ
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![BU of 7lqj by Molmil](/molmil-images/mine/7lqj) | Crystal structure of LeuT bound to L-Alanine | Descriptor: | ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Font, J, Aguilar, J, Galli, A, Ryan, R. | Deposit date: | 2021-02-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.144 Å) | Cite: | Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia. Elife, 10, 2021
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7LQL
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![BU of 7lql by Molmil](/molmil-images/mine/7lql) | Crystal structure of the R375D mutant of LeuT | Descriptor: | ALANINE, Na(+):neurotransmitter symporter (Snf family), SODIUM ION, ... | Authors: | Font, J, Aguilar, J, Galli, A, Ryan, R. | Deposit date: | 2021-02-13 | Release date: | 2021-05-19 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia. Elife, 10, 2021
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8SC3
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![BU of 8sc3 by Molmil](/molmil-images/mine/8sc3) | |
8SC4
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![BU of 8sc4 by Molmil](/molmil-images/mine/8sc4) | |
8SC1
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![BU of 8sc1 by Molmil](/molmil-images/mine/8sc1) | |
8SC2
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![BU of 8sc2 by Molmil](/molmil-images/mine/8sc2) | |
8SC6
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![BU of 8sc6 by Molmil](/molmil-images/mine/8sc6) | Human OCT1 bound to thiamine in inward-open conformation | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Solute carrier family 22 member 1 | Authors: | Zeng, Y.C, Sobti, M, Stewart, A.G. | Deposit date: | 2023-04-04 | Release date: | 2023-10-18 | Last modified: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural basis of promiscuous substrate transport by Organic Cation Transporter 1. Nat Commun, 14, 2023
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