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1AN4
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STRUCTURE AND FUNCTION OF THE B/HLH/Z DOMAIN OF USF
分子名称: DNA (5'-D(*CP*AP*CP*CP*CP*GP*GP*TP*CP*AP*CP*GP*TP*GP*GP*CP*C P*TP*AP*CP*A)-3'), DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*CP*CP*AP*CP*GP*TP*GP*AP*CP*C P*GP*GP*GP*T)-3'), PROTEIN (UPSTREAM STIMULATORY FACTOR)
著者Ferre-D'Amare, A.R, Pognonec, P, Roeder, R.G, Burley, S.K.
登録日1997-03-15
公開日1997-09-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structure and function of the b/HLH/Z domain of USF.
EMBO J., 13, 1994
1CDW
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BU of 1cdw by Molmil
HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA
分子名称: DNA (5'-D(*CP*AP*GP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*CP*TP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP))
著者Nikolov, D.B, Chen, H, Halay, E.D, Hoffmann, A, Roeder, R.G, Burley, S.K.
登録日1996-04-11
公開日1996-12-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of a human TATA box-binding protein/TATA element complex.
Proc.Natl.Acad.Sci.USA, 93, 1996
1J2X
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Crystal structure of RAP74 C-terminal domain complexed with FCP1 C-terminal peptide
分子名称: RNA polymerase II CTD phosphatase, SULFATE ION, Transcription initiation factor IIF, ...
著者Kamada, K, Roeder, R.G, Burley, S.K.
登録日2003-01-15
公開日2003-01-30
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Molecular mechanism of recruitment of TFIIF- associating RNA polymerase C-terminal domain phosphatase (FCP1) by transcription factor IIF
Proc.Natl.Acad.Sci.USA, 100, 2003
6DRD
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BU of 6drd by Molmil
RNA Pol II(G)
分子名称: DNA-directed RNA polymerase II subunit GRINL1A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11-a, ...
著者Yu, X, Jishage, M, Shi, Y, Ganesan, S, Sali, A, Chait, B.T, Asturias, F, Roeder, R.G.
登録日2018-06-11
公開日2019-06-12
最終更新日2019-12-04
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.
Nat. Struct. Mol. Biol., 25, 2018
2H7B
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BU of 2h7b by Molmil
Solution structure of the eTAFH domain from the human leukemia-associated fusion protein AML1-ETO
分子名称: Core-binding factor, ML1-ETO
著者Plevin, M.J, Zhang, J, Guo, C, Roeder, R.G, Ikura, M.
登録日2006-06-01
公開日2006-07-11
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献The acute myeloid leukemia fusion protein AML1-ETO targets E proteins via a paired amphipathic helix-like TBP-associated factor homology domain
Proc.Natl.Acad.Sci.USA, 103, 2006
1TAF
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DROSOPHILA TBP ASSOCIATED FACTORS DTAFII42/DTAFII62 HETEROTETRAMER
分子名称: TFIID TBP ASSOCIATED FACTOR 42, TFIID TBP ASSOCIATED FACTOR 62, ZINC ION
著者Xie, X, Kokubo, T, Cohen, S.L, Mirza, U.A, Hoffmann, A, Chait, B.T, Roeder, R.G, Nakatani, Y, Burley, S.K.
登録日1996-06-01
公開日1996-12-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural similarity between TAFs and the heterotetrameric core of the histone octamer.
Nature, 380, 1996
1VOL
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TFIIB (HUMAN CORE DOMAIN)/TBP (A.THALIANA)/TATA ELEMENT TERNARY COMPLEX
分子名称: DNA (5'-D(*CP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*G)-3'), PROTEIN (TATA BINDING PROTEIN (TBP)), ...
著者Nikolov, D.B, Chen, H, Halay, E.D, Usheva, A.U, Hisatake, K, Lee, D.K, Roeder, R.G, Burley, S.K.
登録日1996-04-29
公開日1996-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of a TFIIB-TBP-TATA-element ternary complex.
Nature, 377, 1995
1I27
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF THE RAP74 SUBUNIT OF HUMAN TRANSCRIPTION FACTOR IIF (TFIIF)
分子名称: TRANSCRIPTION FACTOR IIF, ZINC ION
著者Kamada, K, De Angelis, J, Roeder, R.G, Burley, S.K.
登録日2001-02-07
公開日2001-03-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Crystal structure of the C-terminal domain of the RAP74 subunit of human transcription factor IIF.
Proc.Natl.Acad.Sci.USA, 98, 2001
1JFI
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Crystal Structure of the NC2-TBP-DNA Ternary Complex
分子名称: 5'-D(*G*GP*AP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*TP*CP*C)-3', TATA-BOX-BINDING PROTEIN (TBP), ...
著者Kamada, K, Shu, F, Chen, H, Malik, S, Stelzer, G, Roeder, R.G, Meisterernst, M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2001-06-20
公開日2001-07-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structure of negative cofactor 2 recognizing the TBP-DNA transcription complex.
Cell(Cambridge,Mass.), 106, 2001
7XUR
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The cryo-EM structure of human mini-SNAPc in complex with hU6-1 PSE
分子名称: DNA (35-MER), ZINC ION, snRNA-activating protein complex subunit 1, ...
著者Wang, W, Sun, J.F.
登録日2022-05-19
公開日2022-12-07
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter.
Nat Commun, 13, 2022
7XGW
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Apo structure of LW domain from Trypanosoma brucei
分子名称: Transcription elongation factor s-II
著者Liao, S, Gao, J, Chen, M, Tu, X.
登録日2022-04-06
公開日2023-05-31
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
8I60
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Crystal structure of GAS41 YEATS domain in complex with histone H3K27cr
分子名称: ALA-ARG-KCR-SER-ALA-PRO, GLYCEROL, SULFATE ION, ...
著者Konuma, T, Zhou, M.-M.
登録日2023-01-26
公開日2023-07-26
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Mol.Cell, 83, 2023
4JOL
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Complex structure of AML1-ETO NHR2 domain with HEB fragment
分子名称: Protein CBFA2T1, Transcription factor 12
著者Wang, Z, Patel, D.J.
登録日2013-03-18
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.906 Å)
主引用文献A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.
Nature, 500, 2013
6ZLY
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Crystal structure of the complex between PPARgamma LBD and the ligand NV1362 (7a)
分子名称: (2~{S})-2-[(4-hexoxyphenyl)carbonylamino]-3-methyl-butanoic acid, Peroxisome proliferator-activated receptor gamma
著者Pochetti, G, Montanari, R, Capelli, D.
登録日2020-07-01
公開日2020-11-25
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
6O7G
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Solution structure of MLL4 PHD6 domain in complex with histone H4K16ac peptide
分子名称: Histone H4, Histone-lysine N-methyltransferase 2D, ZINC ION
著者Zhang, Y, Kutateladze, T.G.
登録日2019-03-07
公開日2019-05-22
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.
Nat Commun, 10, 2019
7FAX
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Complex structure of TbLeo1 and LW domain from Trypanosoma brucei
分子名称: TbLW, TbLeo1 peptide
著者Liao, S, Gao, J, Tu, X.
登録日2021-07-07
公開日2022-07-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
7FAW
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Structure of LW domain from Yeast
分子名称: Transcription elongation factor S-II
著者Liao, S, Gao, J, Tu, X.
登録日2021-07-07
公開日2022-07-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.438 Å)
主引用文献Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Int.J.Biol.Macromol., 253, 2023
6AF0
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Structure of Ctr9, Paf1 and Cdc73 ternary complex from Myceliophthora thermophila
分子名称: Cdc73 protein, Ctr9 protein, Paf1 protein
著者Wang, Z, Deng, P, Zhou, Y.
登録日2018-08-07
公開日2018-09-19
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Transcriptional elongation factor Paf1 core complex adopts a spirally wrapped solenoidal topology.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5HJB
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AF9 YEATS in complex with histone H3 Crotonylation at K9
分子名称: Protein AF-9, peptide of Histone H3.1
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-12
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
5HJD
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AF9 YEATS in complex with histone H3 Crotonylation at K18
分子名称: COPPER (II) ION, Protein AF-9, SULFATE ION, ...
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-13
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain.
Mol.Cell, 62, 2016
5HJC
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BRD3 second bromodomain in complex with histone H3 acetylation at K18
分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 3, CHLORIDE ION, ...
著者Li, Y.Y, Zhao, D, Guan, H.P, Li, H.T.
登録日2016-01-13
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain
Mol.Cell, 62, 2016
6QJ5
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X-ray structure of PPARgamma LBD with the ligand NV1380
分子名称: (2~{S})-3-methyl-2-[(4-octoxyphenyl)carbonylamino]butanoic acid, Peroxisome proliferator-activated receptor gamma
著者Pochetti, G, Montanari, R, Capelli, D.
登録日2019-01-22
公開日2020-02-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Novel N-Substituted Valine Derivative with Unique Peroxisome Proliferator-Activated Receptor gamma Binding Properties and Biological Activities.
J.Med.Chem., 63, 2020
1C9B
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CRYSTAL STRUCTURE OF A HUMAN TBP CORE DOMAIN-HUMAN TFIIB CORE DOMAIN COMPLEX BOUND TO AN EXTENDED, MODIFIED ADENOVIRAL MAJOR LATE PROMOTER (ADMLP)
分子名称: ADMLP TATA-BOX DNA CONTAINING IIB RECOGNITION ELEMENT, GENERAL TRANSCRIPTION FACTOR IIB, TATA BOX BINDING PROTEIN
著者Tsai, F.T.F, Sigler, P.B.
登録日1999-08-01
公開日2000-01-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis of preinitiation complex assembly on human pol II promoters.
EMBO J., 19, 2000
1TFB
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NMR STUDIES OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB: DYNAMICS AND INTERACTION WITH VP16 ACTIVATION DOMAIN, 20 STRUCTURES
分子名称: TFIIB
著者Bagby, S, Ikura, M.
登録日1996-11-14
公開日1997-03-12
最終更新日2022-03-02
実験手法SOLUTION NMR
主引用文献Human general transcription factor TFIIB: conformational variability and interaction with VP16 activation domain.
Biochemistry, 37, 1998
1TBP
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CRYSTAL STRUCTURE OF YEAST TATA-BINDING PROTEIN AND MODEL FOR INTERACTION WITH DNA
分子名称: TATA-BINDING PROTEIN
著者Chasman, D.I, Flaherty, K.M, Sharp, P.A, Kornberg, R.D.
登録日1993-08-02
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of yeast TATA-binding protein and model for interaction with DNA.
Proc.Natl.Acad.Sci.USA, 90, 1993

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