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3ME2
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BU of 3me2 by Molmil
Crystal structure of mouse RANKL-RANK complex
Descriptor: CHLORIDE ION, SODIUM ION, Tumor necrosis factor ligand superfamily member 11, ...
Authors:Walter, S.W, Liu, C.Z, Zhu, X.K, Wu, Y, Owens, R.J, Stuart, D.I, Gao, B, Ren, J.
Deposit date:2010-03-31
Release date:2010-06-02
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural and Functional Insights of RANKL-RANK Interaction and Signaling.
J.Immunol., 2010
3OC2
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BU of 3oc2 by Molmil
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa
Descriptor: CHLORIDE ION, Penicillin-binding protein 3
Authors:Sainsbury, S, Bird, L, Stuart, D.I, Owens, R.J, Ren, J, Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-09
Release date:2010-11-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3OCN
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BU of 3ocn by Molmil
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with ceftazidime
Descriptor: 1-({(2R)-2-[(1R)-1-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-2-oxoethyl]-4-carboxy-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, penicillin-binding protein 3
Authors:Sainsbury, S, Bird, L, Stuart, D.I, Owens, R.J, Ren, J, Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-10
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
3OCL
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BU of 3ocl by Molmil
Crystal structure of penicillin-binding protein 3 from Pseudomonas aeruginosa in complex with carbenicillin
Descriptor: (2R,4S)-2-[(1R)-1-{[(2S)-2-carboxy-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Sainsbury, S, Bird, L, Stuart, D.I, Owens, R.J, Ren, J, Oxford Protein Production Facility (OPPF)
Deposit date:2010-08-10
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
J.Mol.Biol., 405, 2011
4I2X
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BU of 4i2x by Molmil
Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, FabOX117 heavy chain, ...
Authors:Nettleship, J.E, Ren, J, Stuart, D.I, Owens, R.J, Oxford Protein Production Facility (OPPF)
Deposit date:2012-11-23
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal structure of signal regulatory protein gamma (SIRP gamma) in complex with an antibody Fab fragment.
Bmc Struct.Biol., 13, 2013
4ILE
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BU of 4ile by Molmil
Structure of human ADP-ribosylation factor-like 8A binding to GDP
Descriptor: ADP-ribosylation factor-like protein 8A, GUANOSINE-5'-DIPHOSPHATE
Authors:Xie, Y, Ren, J, Cheng, Z, Qian, H.
Deposit date:2012-12-31
Release date:2014-01-01
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.676 Å)
Cite:Structure of human ADP-ribosylation factor-like 8A binding to GDP
To be Published
4IV1
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BU of 4iv1 by Molmil
Crystal structure of recombinant foot-and-mouth-disease virus A22 empty capsid
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B.
Deposit date:2013-01-22
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
4IV3
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BU of 4iv3 by Molmil
Crystal structure of recombinant foot-and-mouth-disease virus A22-H2093C empty capsid
Descriptor: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
Authors:Porta, C, Kotecha, A, Burman, A, Jackson, T, Ren, J, Loureiro, S, Jones, I.M, Fry, E.E, Stuart, D.I, Charleston, B.
Deposit date:2013-01-22
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Rational engineering of recombinant picornavirus capsids to produce safe, protective vaccine antigen.
Plos Pathog., 9, 2013
8B9F
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BU of 8b9f by Molmil
Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion
Descriptor: Complement decay-accelerating factor, Genome polyprotein, SPHINGOSINE
Authors:Stuart, D.I, Ren, J, Qin, L, Zhou, D.
Deposit date:2022-10-05
Release date:2022-12-07
Last modified:2023-01-04
Method:ELECTRON MICROSCOPY (3.93 Å)
Cite:Switching of Receptor Binding Poses between Closely Related Enteroviruses.
Viruses, 14, 2022
8B8R
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BU of 8b8r by Molmil
Complex of Echovirus 11 with its attaching receptor decay-accelerating factor (CD55)
Descriptor: DECAY ACCELERATING FACTOR (CD55), SPHINGOSINE, VP1, ...
Authors:Stuart, D.I, Ren, J, Zhou, D, Qin, L.
Deposit date:2022-10-04
Release date:2022-12-07
Last modified:2023-01-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Switching of Receptor Binding Poses between Closely Related Enteroviruses.
Viruses, 14, 2022
4WYU
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BU of 4wyu by Molmil
Crystal Structure of Scribble PDZ34 tandem in complex with its target peptide
Descriptor: IODIDE ION, Protein scribble homolog, peptide SER-TRP-PHE-GLN-THR-ASP-LEU
Authors:Ren, J.Q, Pei, H.H, Feng, W.
Deposit date:2014-11-18
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
Biochem.J., 468, 2015
5ZBS
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BU of 5zbs by Molmil
Crystal Structure of Kinesin-3 KIF13B motor Y73C mutant
Descriptor: Kinesin family member 13B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Ren, J.Q, Wang, S, Feng, W.
Deposit date:2018-02-12
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement.
J. Mol. Biol., 430, 2018
5ZBR
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BU of 5zbr by Molmil
Crystal Structure of Kinesin-3 KIF13B motor domain in AMPPNP form
Descriptor: Kinesin family member 13B, MAGNESIUM ION, PHOSPHATE ION, ...
Authors:Ren, J.Q, Wang, S, Feng, W.
Deposit date:2018-02-12
Release date:2018-05-30
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Delineation of the Neck Linker of Kinesin-3 for Processive Movement.
J. Mol. Biol., 430, 2018
5DJO
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BU of 5djo by Molmil
Crystal structure of the CC1-FHA tandem of Kinesin-3 KIF13A
Descriptor: ACETIC ACID, DI(HYDROXYETHYL)ETHER, FORMIC ACID, ...
Authors:Ren, J.Q, Li, W, Huo, L, Feng, W.
Deposit date:2015-09-02
Release date:2015-12-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A
J.Biol.Chem., 291, 2016
5DJN
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BU of 5djn by Molmil
Crystal structure of the Kinesin-3 KIF13A NC-CC1 mutant - Deletion of P390
Descriptor: Kinesin-like protein
Authors:Ren, J.Q, Feng, W.
Deposit date:2015-09-02
Release date:2015-12-30
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural Correlation of the Neck Coil with the Coiled-coil (CC1)-Forkhead-associated (FHA) Tandem for Active Kinesin-3 KIF13A
J.Biol.Chem., 291, 2016
4WYT
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BU of 4wyt by Molmil
Crystal Structure of Scribble PDZ34 tandem at 2.6 Angstroms
Descriptor: CHLORIDE ION, Protein scribble homolog
Authors:Ren, J.Q, Feng, W.
Deposit date:2014-11-18
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Interdomain interface-mediated target recognition by the Scribble PDZ34 supramodule.
Biochem.J., 468, 2015
7WEK
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BU of 7wek by Molmil
Crystal structure of the mouse Wdr47 NTD in complex with the WBR motif form Camsap3.
Descriptor: WBR motif form Calmodulin-regulated spectrin-associated protein 3, WD repeat-containing protein 47
Authors:Ren, J.Q, Li, D, Feng, W.
Deposit date:2021-12-23
Release date:2022-11-30
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation.
Cell Rep, 41, 2022
7WEJ
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BU of 7wej by Molmil
Crystal structure of the mouse Wdr47 NTD.
Descriptor: WD repeat-containing protein 47
Authors:Ren, J.Q, Li, D, Feng, W.
Deposit date:2021-12-23
Release date:2022-11-30
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Intertwined Wdr47-NTD dimer recognizes a basic-helical motif in Camsap proteins for proper central-pair microtubule formation.
Cell Rep, 41, 2022
6KLR
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BU of 6klr by Molmil
Crystal structure of human WIPI3 in complex with the WIR-peptide from ATG2A
Descriptor: chimera ATG2A and WIPI3
Authors:Ren, J.Q, Liang, R.B, Feng, W.
Deposit date:2019-07-30
Release date:2020-04-29
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Multi-site-mediated entwining of the linear WIR-motif around WIPI beta-propellers for autophagy.
Nat Commun, 11, 2020
7RA9
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BU of 7ra9 by Molmil
Designed StabIL-2 seq1
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Interleukin-2, PHOSPHATE ION
Authors:Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C.
Deposit date:2021-06-30
Release date:2022-03-16
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RAA
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BU of 7raa by Molmil
Designed StabIL-2 seq15
Descriptor: Interleukin-2, MAGNESIUM ION
Authors:Jude, K.M, Chu, A.E, Huang, P.-S, Garcia, K.C.
Deposit date:2021-06-30
Release date:2022-03-16
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Interleukin-2 superkines by computational design.
Proc.Natl.Acad.Sci.USA, 119, 2022
4M8Z
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BU of 4m8z by Molmil
Crystal Structure of SFH3, a phosphatidylinositol transfer protein that integrates phosphoinositide signaling with lipid droplet metabolism
Descriptor: Phosphatidylinositol transfer protein PDR16
Authors:Ortlund, E.O, Pathak, M.C.
Deposit date:2013-08-14
Release date:2014-09-10
Last modified:2019-07-17
Method:X-RAY DIFFRACTION (1.928 Å)
Cite:A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis.
Mol Biol Cell, 25, 2014
1A4V
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BU of 1a4v by Molmil
ALPHA-LACTALBUMIN
Descriptor: ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Chandra, N, Acharya, K.R.
Deposit date:1998-02-05
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin.
Biochemistry, 37, 1998
6ZH9
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BU of 6zh9 by Molmil
Ternary complex CR3022 H11-H4 and RBD (SARS-CoV-2)
Descriptor: CR3022 Light chain, CR3022 heavy, Nanobody H11-H4, ...
Authors:Naismith, J.H, Mikolajek, H, Le Bas, A.
Deposit date:2020-06-21
Release date:2020-09-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2.
Nat.Struct.Mol.Biol., 27, 2020
6XXR
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BU of 6xxr by Molmil
ENAH EVH1 in complex with Ac-[2-Cl-F]-PPPPTEDEA-NH2
Descriptor: Ac-[2-Cl-F]-PPPPTEDEA-NH2, NITRATE ION, Protein enabled homolog
Authors:Barone, M, Le Cong, K, Roske, Y.
Deposit date:2020-01-28
Release date:2020-11-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Proc.Natl.Acad.Sci.USA, 117, 2020

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