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1K2Y
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BU of 1k2y by Molmil
Crystal Structure of Phosphomannomutase/Phosphoglucomutase S108A mutant from P. aeruginosa
Descriptor: L(+)-TARTARIC ACID, ZINC ION, phosphomannomutase
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2001-09-30
Release date:2002-02-13
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of PMM/PGM: an enzyme in the biosynthetic pathway of P. aeruginosa virulence factors.
Structure, 10, 2002
1K35
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BU of 1k35 by Molmil
Crystal Structure of Phosphomannomutase/Phosphoglucomutase from P.aeruginosa
Descriptor: Phosphomannomutase, ZINC ION
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2001-10-01
Release date:2002-02-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of PMM/PGM: an enzyme in the biosynthetic pathway of P. aeruginosa virulence factors.
Structure, 10, 2002
1P5D
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BU of 1p5d by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
Descriptor: 1-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase, ZINC ION
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2003-04-25
Release date:2004-01-20
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
1P5G
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BU of 1p5g by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase, ZINC ION
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2003-04-26
Release date:2004-01-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
1PCJ
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BU of 1pcj by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
Descriptor: 1-O-phosphono-alpha-D-mannopyranose, Phosphomannomutase, ZINC ION
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2003-05-16
Release date:2004-01-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
1PCM
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BU of 1pcm by Molmil
Enzyme-ligand complex of P. aeruginosa PMM/PGM
Descriptor: 6-O-phosphono-alpha-D-mannopyranose, Phosphomannomutase, ZINC ION
Authors:Regni, C, Tipton, P.A, Beamer, L.J.
Deposit date:2003-05-16
Release date:2004-01-20
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of diverse substrate recognition by the enzyme PMM/PGM from P. aeruginosa.
Structure, 12, 2004
2H5A
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BU of 2h5a by Molmil
Complex of the enzyme PMM/PGM with xylose 1-phosphate
Descriptor: 1-O-phosphono-alpha-D-xylopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
Authors:Regni, C, Shackelford, G.S, Beamer, L.J.
Deposit date:2006-05-25
Release date:2006-08-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor.
Acta Crystallogr.,Sect.F, 62, 2006
2FKF
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BU of 2fkf by Molmil
Phosphomannomutase/Phosphoglucomutase from Pseudomonas aeruginosa with alpha-D-glucose 1,6-bisphosphate bound
Descriptor: 1,6-di-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
Authors:Regni, C.A, Beamer, L.J.
Deposit date:2006-01-04
Release date:2006-04-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.
J.Biol.Chem., 281, 2006
2FKM
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BU of 2fkm by Molmil
PMM/PGM S108D mutant with alpha-d-glucose 1,6-bisphosphate bound
Descriptor: 1,6-di-O-phosphono-alpha-D-glucopyranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
Authors:Regni, C.A, Beamer, L.J.
Deposit date:2006-01-04
Release date:2006-04-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The reaction of phosphohexomutase from Pseudomonas aeruginosa: structural insights into a simple processive enzyme.
J.Biol.Chem., 281, 2006
2H4L
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BU of 2h4l by Molmil
Complex of PMM/PGM with ribose 1-phosphate
Descriptor: 1-O-phosphono-alpha-D-ribofuranose, Phosphomannomutase/phosphoglucomutase, ZINC ION
Authors:Beamer, L.J.
Deposit date:2006-05-24
Release date:2006-08-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Complexes of the enzyme phosphomannomutase/phosphoglucomutase with a slow substrate and an inhibitor.
Acta Crystallogr.,Sect.F, 62, 2006
7OH1
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BU of 7oh1 by Molmil
Tetanus neurotoxin LC-HN domain in complex with TT110-Fab1
Descriptor: FAB TT110, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021
7OH0
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BU of 7oh0 by Molmil
Tetanus neurotoxin HC domain in complex with TT104-Fab1
Descriptor: Fab TT104, Tetanus toxin
Authors:Grinzato, A, Kandiah, E, Zanotti, G.
Deposit date:2021-05-07
Release date:2021-10-27
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice.
J.Clin.Invest., 131, 2021
8S9G
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BU of 8s9g by Molmil
SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Fab Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-03-28
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8FXB
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BU of 8fxb by Molmil
SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-01-24
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8FXC
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BU of 8fxc by Molmil
SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, S309 Heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2023-01-24
Release date:2023-10-04
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Neutralization, effector function and immune imprinting of Omicron variants.
Nature, 621, 2023
8ERR
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BU of 8err by Molmil
SARS-CoV-2 Omicron BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 heavy chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
8ERQ
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BU of 8erq by Molmil
SARS-CoV-2 BA.1 spike ectodomain trimer in complex with the S2X324 neutralizing antibody Fab fragment (local refinement of the RBD and S2X324)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2X324 Fab heavy chain, S2X324 Fab light chain, ...
Authors:Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2022-10-12
Release date:2022-10-26
Last modified:2022-11-23
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Imprinted antibody responses against SARS-CoV-2 Omicron sublineages.
Science, 378, 2022
7N8I
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BU of 7n8i by Molmil
SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 (Local Refinement of the NTD/S2L20)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab Heavy Chain Variable Region, S2L20 Fab Light Chain Variable Region, ...
Authors:McCallum, M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:2021-06-14
Release date:2021-07-14
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (3 Å)
Cite:SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.
Science, 373, 2021
7N8H
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BU of 7n8h by Molmil
SARS-CoV-2 S (B.1.429 / epsilon variant) + S2M11 + S2L20 Global Refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-06-14
Release date:2021-07-14
Last modified:2021-08-18
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:SARS-CoV-2 immune evasion by the B.1.427/B.1.429 variant of concern.
Science, 373, 2021
7M7W
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BU of 7m7w by Molmil
Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal antibody S2H97 Fab heavy chain, Monoclonal antibody S2H97 Fab light chain, ...
Authors:Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
Deposit date:2021-03-29
Release date:2021-05-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7RNJ
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BU of 7rnj by Molmil
S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide
Descriptor: Monoclonal antibody S2P6 Fab heavy chain, Monoclonal antibody S2P6 Fab light chain, SULFATE ION, ...
Authors:Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M, Sauer, M.M, Veesler, D.
Deposit date:2021-07-29
Release date:2021-08-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Broad betacoronavirus neutralization by a stem helix-specific human antibody.
Science, 373, 2021
7R7N
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BU of 7r7n by Molmil
SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2D106 FAB heavy chain, S2D106 FAB light chain, ...
Authors:Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2021-06-25
Release date:2021-07-21
Last modified:2021-09-15
Method:ELECTRON MICROSCOPY (3.95 Å)
Cite:SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7R6X
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BU of 7r6x by Molmil
SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2E12 Fab, S309 Fab, and S304 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Monoclonal antibody S2E12 Fab heavy chain, ...
Authors:Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
Deposit date:2021-06-23
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
7R6W
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BU of 7r6w by Molmil
SARS-CoV-2 spike receptor-binding domain (RBD) in complex with S2X35 Fab and S309 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, GLYCEROL, ...
Authors:Snell, G, Czudnochowski, N, Hernandez, P, Nix, J.C, Croll, T.I, Corti, D, Cameroni, E, Pinto, D, Beltramello, M.
Deposit date:2021-06-23
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape.
Nature, 597, 2021
6URM
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BU of 6urm by Molmil
Crystal structure of vaccine-elicited receptor-binding site targeting antibody LPAF-a.01 in complex with Hemagglutinin H1 A/California/04/2009
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Zhou, T, Cheung, S.F, Kwong, P.D.
Deposit date:2019-10-23
Release date:2020-09-16
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation.
Cell Rep, 32, 2020

 

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