4V0M
 
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2XC7
 | | Solution Structure of PHAX-RBD in complex with ssRNA | | 分子名称: | 5'-(AP*UP*CP*GP)-3', PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN | | 著者 | Mourao, A, Mackereth, C.D, Varrot, A, Cusack, S, Sattler, M. | | 登録日 | 2010-04-18 | | 公開日 | 2010-04-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
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4V0O
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4V0N
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4V0L
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4V0K
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8QF0
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5MF9
 | | Solution structure of the RBM5 OCRE domain in complex with polyproline SmN peptide. | | 分子名称: | RNA-binding protein 5, Survival motor neuron protein | | 著者 | Mourao, A, Sattler, M, Bonnal, S, Komal, S, Warner, L, Bordonne, R, Valcarcel, J. | | 登録日 | 2016-11-17 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the recognition ofspliceosomal SmN B B proteins by theRBM5 OCRE domain in splicing regulation
Elife, 5, 2016
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5MFY
 | | RBM5 OCRE domain | | 分子名称: | RNA-binding protein 5 | | 著者 | Warner, L.R, Mourao, A, Soni, K, Sattler, M. | | 登録日 | 2016-11-19 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for the recognition of spliceosomal SmN/B/B' proteins by the RBM5 OCRE domain in splicing regulation.
Elife, 5, 2016
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2W4S
 | | novel RNA-binding domain in Cryptosporidium parvum at 2.5 angstrom resolution | | 分子名称: | Ankyrin-repeat protein | | 著者 | Varrot, A, Mackereth, C, Mourao, A, Sattler, M, Cusack, S. | | 登録日 | 2008-12-02 | | 公開日 | 2009-12-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structure and RNA Recognition by the Snrna and Snorna Transport Factor Phax.
RNA, 16, 2010
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5FMS
 | | mmIFT52 N-terminal domain | | 分子名称: | INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG | | 著者 | Mourao, A, Lorentzen, E. | | 登録日 | 2015-11-09 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.488 Å) | | 主引用文献 | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex.
Embo J., 35, 2016
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5FMR
 | | crIFT52 N-terminal domain | | 分子名称: | INTRAFLAGELLAR TRANSPORT PROTEIN COMPONENT IFT52, SULFATE ION | | 著者 | Mourao, A, Vetter, M, Lorentzen, E. | | 登録日 | 2015-11-09 | | 公開日 | 2016-03-09 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Intraflagellar Transport Proteins 172, 80, 57, 54, 38, and 20 Form a Stable Tubulin-Binding Ift-B2 Complex.
Embo J., 35, 2016
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7NY8
 | | Affimer K69 - KRAS protein complex | | 分子名称: | Affimer K69, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Turner, A.L, Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2021-03-21 | | 公開日 | 2021-07-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
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6YR8
 | | Affimer K6 - KRAS protein complex | | 分子名称: | Affimer K6, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2020-04-19 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
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6YXW
 | | Affimer K3 - KRAS protein complex | | 分子名称: | Affimer K3, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Trinh, C.H, Haza, K.Z, Rao, A, Martin, H.L, Tiede, C, Edwards, T.A, McPherson, M.J, Tomlinson, D.C. | | 登録日 | 2020-05-04 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | | 主引用文献 | RAS-inhibiting biologics identify and probe druggable pockets including an SII-alpha 3 allosteric site.
Nat Commun, 12, 2021
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1PZU
 | | An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site | | 分子名称: | 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', 5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... | | 著者 | Jin, L, Sliz, P, Chen, L, Macian, F, Rao, A, Hogan, P.G, Harrison, S.C. | | 登録日 | 2003-07-14 | | 公開日 | 2003-09-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site
Nat.Struct.Biol., 10, 2003
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2P6B
 | | Crystal Structure of Human Calcineurin in Complex with PVIVIT Peptide | | 分子名称: | CALCIUM ION, Calcineurin subunit B isoform 1, Calmodulin-dependent calcineurin A subunit alpha isoform, ... | | 著者 | Li, H, Zhang, L, Rao, A, Harrison, S.C, Hogan, P.G. | | 登録日 | 2007-03-16 | | 公開日 | 2007-06-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structure of calcineurin in complex with PVIVIT peptide: Portrait of a low-affinity signalling interaction
J.Mol.Biol., 369, 2007
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2AS5
 | | Structure of the DNA binding domains of NFAT and FOXP2 bound specifically to DNA. | | 分子名称: | 5'-D(AP*AP*CP*TP*AP*TP*GP*AP*AP*AP*CP*AP*AP*AP*TP*TP*TP*TP*CP*CP*TP*)-3', 5'-D(TP*TP*AP*GP*GP*AP*AP*AP*AP*TP*TP*TP*GP*TP*TP*TP*CP*AP*TP*AP*GP*)-3', Forkhead box protein P2, ... | | 著者 | Wu, Y, Stroud, J.C, Borde, M, Bates, D.L, Guo, L, Han, A, Rao, A, Chen, L. | | 登録日 | 2005-08-22 | | 公開日 | 2006-08-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | FOXP3 Controls Regulatory T Cell Function through Cooperation with NFAT.
Cell(Cambridge,Mass.), 126, 2006
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1A02
 | | STRUCTURE OF THE DNA BINDING DOMAINS OF NFAT, FOS AND JUN BOUND TO DNA | | 分子名称: | AP-1 FRAGMENT FOS, AP-1 FRAGMENT JUN, DNA (5'-D(*DAP*DAP*DCP*DTP*DAP*DTP*DGP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DTP*DTP*DTP*DTP*DCP*DC)-3'), ... | | 著者 | Chen, L, Glover, J.N.M, Hogan, P.G, Rao, A, Harrison, S.C. | | 登録日 | 1997-12-08 | | 公開日 | 1998-05-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA.
Nature, 392, 1998
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1IMH
 | | TonEBP/DNA COMPLEX | | 分子名称: | 5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*TP*TP*CP*CP*AP*GP*C)-3', 5'-D(*TP*TP*GP*CP*TP*GP*GP*AP*AP*AP*AP*AP*TP*AP*G)-3', NUCLEAR FACTOR OF ACTIVATED T CELLS 5 | | 著者 | Stroud, J.C, Lopez-Rodriguez, C, Rao, A, Chen, L. | | 登録日 | 2001-05-10 | | 公開日 | 2002-02-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.86 Å) | | 主引用文献 | Structure of a TonEBP-DNA complex reveals DNA encircled by a transcription factor.
Nat.Struct.Biol., 9, 2002
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3QRF
 | | Structure of a domain-swapped FOXP3 dimer | | 分子名称: | Forkhead box protein P3, MAGNESIUM ION, Nuclear factor of activated T-cells, ... | | 著者 | Bandukwala, H.S, Wu, Y, Feurer, M, Chen, Y, Barbosa, B, Ghosh, S, Stroud, J.C, Benoist, C, Mathis, D, Rao, A, Chen, L. | | 登録日 | 2011-02-17 | | 公開日 | 2011-04-20 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of a Domain-Swapped FOXP3 Dimer on DNA and Its Function in Regulatory T Cells.
Immunity, 34, 2011
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7NT4
 | | X-ray structure of SCoV2-PLpro in complex with small molecule inhibitor | | 分子名称: | 1,2-ETHANEDIOL, Non-structural protein 3, PROFLAVIN, ... | | 著者 | Napolitano, V, Mourao, A, Bostock, M, Matsuda, A, Czarna, A, Popowicz, G.M. | | 登録日 | 2021-03-09 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses.
Cell Chem Biol, 29, 2022
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8Q8J
 | | Crystal structure of human GPX4-R152H | | 分子名称: | Glutathione peroxidase | | 著者 | Napolitano, V, Mourao, A, Kolonko, M, Bostock, M.J, Sattler, M, Conrad, M, Popowicz, G. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of human GPX4-R152H
To Be Published
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8Q8N
 | | Crystal structure of human GPX4-U46C-I129S-L130S | | 分子名称: | Phospholipid hydroperoxide glutathione peroxidase | | 著者 | Bostock, M.J, Mourao, A, Napolitano, V, Sattler, M, Conrad, M, Popowicz, G. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | An ultra-rare variant of GPX4 reveals the structural basis to avert neurodegeneration
To Be Published
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5N4A
 | | Crystal structure of Chlamydomonas IFT80 | | 分子名称: | GLYCEROL, Intraflagellar transport protein 80, OXALATE ION | | 著者 | Taschner, M, Mourao, A. | | 登録日 | 2017-02-10 | | 公開日 | 2018-02-28 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Crystal structure of intraflagellar transport protein 80 reveals a homo-dimer required for ciliogenesis.
Elife, 7, 2018
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