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2G44
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BU of 2g44 by Molmil
Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-1M-G and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide
Descriptor: 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L.
Deposit date:2006-02-21
Release date:2007-01-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Discovery and characterization of novel estrogen receptor agonist ligands and development of biochips for nuclear receptor drug discovery
Thesis, 2006
2G5O
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BU of 2g5o by Molmil
Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide
Descriptor: (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1-YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, Estrogen receptor, Nuclear receptor coactivator 2
Authors:Rajan, S.S, Hsieh, R.W, Sharma, S.K, Greene, G.L.
Deposit date:2006-02-23
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Human estrogen receptor alpha ligand-binding domain in complex with 2-(but-1-enyl)-17beta-estradiol and a glucocorticoid receptor interacting protein 1 NR BOX II Peptide
To be Published
2H7H
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BU of 2h7h by Molmil
Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA
Descriptor: 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*CP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*GP*AP*TP*GP*AP*GP*TP*CP*AP*TP*CP*GP*AP*CP*G)-3', Viral jun transforming protein
Authors:Rajan, S.S, Borovilos, M, Cuff, M.E, Kim, Y.
Deposit date:2006-06-02
Release date:2007-06-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the JUN BZIP homodimer complexed with AP-1 DNA
To be Published
2F8W
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BU of 2f8w by Molmil
Crystal structure of d(CACGTG)2
Descriptor: 1,3-DIAMINOPROPANE, 5'-D(*CP*AP*CP*GP*TP*G)-3', SPERMINE
Authors:Narayana, N, Shamala, N, Ganesh, K.N, Viswamitra, M.A.
Deposit date:2005-12-04
Release date:2006-01-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Interaction between the Z-Type DNA Duplex and 1,3-Propanediamine: Crystal Structure of d(CACGTG)2 at 1.2 A Resolution
Biochemistry, 45, 2006
6CBZ
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BU of 6cbz by Molmil
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Estradiol and GRIP Peptide
Descriptor: ESTRADIOL, Estrogen receptor, GLYCEROL, ...
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2018-02-05
Release date:2018-02-28
Last modified:2020-02-26
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
5W9C
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BU of 5w9c by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S in Complex with 4-hydroxytamoxifen
Descriptor: 4-HYDROXYTAMOXIFEN, Estrogen receptor
Authors:Fanning, S.W, Greene, G.W.
Deposit date:2017-06-23
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.802 Å)
Cite:Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
5W9D
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BU of 5w9d by Molmil
Estrogen Receptor Alpha Ligand Binding Domain C381S, C417S, C530S Mutant in Complex with Endoxifen
Descriptor: Endoxifen, Estrogen receptor
Authors:Fanning, S.W, Greene, G.L.
Deposit date:2017-06-23
Release date:2017-10-11
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.6464 Å)
Cite:Endoxifen, 4-Hydroxytamoxifen and an Estrogenic Derivative Modulate Estrogen Receptor Complex Mediated Apoptosis in Breast Cancer.
Mol. Pharmacol., 94, 2018
1MCO
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BU of 1mco by Molmil
THREE-DIMENSIONAL STRUCTURE OF A HUMAN IMMUNOGLOBULIN WITH A HINGE DELETION
Descriptor: IGG1 MCG INTACT ANTIBODY (HEAVY CHAIN), IGG1 MCG INTACT ANTIBODY (LIGHT CHAIN), N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-L-gulopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Guddat, L.W, Edmundson, A.B.
Deposit date:1993-02-25
Release date:1994-01-31
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Three-dimensional structure of a human immunoglobulin with a hinge deletion.
Proc.Natl.Acad.Sci.Usa, 90, 1993
1MCW
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BU of 1mcw by Molmil
THREE-DIMENSIONAL STRUCTURE OF A HYBRID LIGHT CHAIN DIMER. PROTEIN ENGINEERING OF A BINDING CAVITY
Descriptor: IMMUNOGLOBULIN MCG (LIGHT CHAIN), IMMUNOGLOBULIN WEIR (LIGHT CHAIN)
Authors:Ely, K.R, Herron, J.N, Edmundson, A.B.
Deposit date:1989-05-09
Release date:1990-10-15
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Three-dimensional structure of a hybrid light chain dimer: protein engineering of a binding cavity.
Mol.Immunol., 27, 1990
1UP7
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BU of 1up7 by Molmil
Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.4 Angstrom resolution in the tetragonal form with NAD and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J.
Deposit date:2003-09-29
Release date:2004-11-18
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Nad+ and Metal-Ion Dependent Hydrolysis by Family 4 Glycosidases: Structural Insight Into Specificity for Phospho-Beta-D-Glucosides
J.Mol.Biol., 346, 2005
1UP4
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BU of 1up4 by Molmil
Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.85 Angstrom resolution in the monoclinic form
Descriptor: 6-PHOSPHO-BETA-GLUCOSIDASE
Authors:Varrot, A, Yip, V, Withers, S.G, Davies, G.J.
Deposit date:2003-09-26
Release date:2004-11-18
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Nad+ and Metal-Ion Dependent Hydrolysis by Family 4 Glycosidases: Structural Insight Into Specificity for Phospho-Beta-D-Glucosides
J.Mol.Biol., 346, 2005
1UP6
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BU of 1up6 by Molmil
Structure of the 6-phospho-beta glucosidase from Thermotoga maritima at 2.55 Angstrom resolution in the tetragonal form with manganese, NAD+ and glucose-6-phosphate
Descriptor: 6-O-phosphono-alpha-D-glucopyranose, 6-PHOSPHO-BETA-GLUCOSIDASE, MANGANESE (II) ION, ...
Authors:Varrot, A, Yip, V.L, Withers, S.G, Davies, G.J.
Deposit date:2003-09-29
Release date:2004-08-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:An Unusual Mechanism of Glycoside Hydrolysis Involving Redox and Elimination Steps by a Family 4 Beta-Glycosidase from Thermotoga Maritima.
J.Am.Chem.Soc., 126, 2004
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