1LUD
 
 | | SOLUTION STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH TRIMETHOPRIM AND NADPH, 24 STRUCTURES | | 分子名称: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, DIHYDROFOLATE REDUCTASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Polshakov, V.I, Smirnov, E.G, Birdsall, B, Kelly, G, Feeney, J. | | 登録日 | 2002-05-22 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR-based solution structure of the complex of Lactobacillus casei dihydrofolate reductase with trimethoprim and NADPH
J.Biomol.Nmr, 24, 2002
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1BZF
 | | NMR SOLUTION STRUCTURE AND DYNAMICS OF THE COMPLEX OF LACTOBACILLUS CASEI DIHYDROFOLATE REDUCTASE WITH THE NEW LIPOPHILIC ANTIFOLATE DRUG TRIMETREXATE, 22 STRUCTURES | | 分子名称: | DIHYDROFOLATE REDUCTASE, TRIMETREXATE | | 著者 | Polshakov, V.I, Birdsall, B, Frenkiel, T.A, Gargaro, A.R, Feeney, J. | | 登録日 | 1998-10-28 | | 公開日 | 1999-05-18 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reductase with the new lipophilic antifolate drug trimetrexate.
Protein Sci., 8, 1999
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5LFY
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2LLX
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1PS2
 | | HIGH RESOLUTION NMR SOLUTION STRUCTURE OF HUMAN PS2, 19 STRUCTURES | | 分子名称: | PS2 | | 著者 | Williams, M.A, Polshakov, V.I, Gargaro, A.R, Feeney, J. | | 登録日 | 1997-01-07 | | 公開日 | 1997-07-07 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | High-resolution solution structure of human pNR-2/pS2: a single trefoil motif protein.
J.Mol.Biol., 267, 1997
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5LGF
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1YHO
 | | Solution structure of human dihydrofolate reductase complexed with trimethoprim and nadph, 25 structures | | 分子名称: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Polshakov, V.I, Birdsall, B. | | 登録日 | 2005-01-10 | | 公開日 | 2005-11-22 | | 最終更新日 | 2022-03-02 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of human dihydrofolate reductase in its complex with trimethoprim and NADPH.
J.Biomol.Nmr, 33, 2005
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7QCB
 | | Williams-Beuren syndrome related methyltransferase WBSCR27 in complex with SAH | | 分子名称: | Methyltransferase-like 27, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Polshakov, V.I, Mariasina, S.S, Chang, C.-F, Efimov, S.V. | | 登録日 | 2021-11-23 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Williams-Beuren Syndrome Related Methyltransferase WBSCR27: From Structure to Possible Function.
Front Mol Biosci, 9, 2022
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7QCC
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2L28
 | | Solution structure of lactobacillus casei dihydrofolate reductase apo-form, 25 conformers | | 分子名称: | Dihydrofolate reductase | | 著者 | Polshakov, V.I, Birdsall, B, Feeney, J. | | 登録日 | 2010-08-13 | | 公開日 | 2011-04-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structures of Apo L. casei Dihydrofolate Reductase and Its Complexes with Trimethoprim and NADPH: Contributions to Positive Cooperative Binding from Ligand-Induced Refolding, Conformational Changes, and Interligand Hydrophobic Interactions.
Biochemistry, 50, 2011
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2HQP
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2HM9
 | | Solution structure of dihydrofolate reductase complexed with trimethoprim, 33 structures | | 分子名称: | 2,4-DIAMINO-5-(3,4,5-TRIMETHOXY-BENZYL)-PYRIMIDIN-1-IUM, Dihydrofolate reductase | | 著者 | Polshakov, V.I, Birdsall, B. | | 登録日 | 2006-07-11 | | 公開日 | 2007-06-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of apo L.casei dihydrofolate reductase and its complexes with trimethoprim and NADPH. Contributions to positive cooperative binding from ligand-induced refolding, conformational changes and interligand hydrophobic interactions
Biochemistry, 2011
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2HST
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1AO8
 | | DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE, NMR, 21 STRUCTURES | | 分子名称: | DIHYDROFOLATE REDUCTASE, METHOTREXATE | | 著者 | Gargaro, A.R, Soteriou, A, Frenkiel, T.A, Bauer, C.J, Birdsall, B, Polshakov, V.I, Barsukov, I.L, Roberts, G.C.K, Feeney, J. | | 登録日 | 1997-07-22 | | 公開日 | 1998-02-25 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The solution structure of the complex of Lactobacillus casei dihydrofolate reductase with methotrexate.
J.Mol.Biol., 277, 1998
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1DIS
 | | DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE | | 分子名称: | BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE | | 著者 | Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J. | | 登録日 | 1995-08-01 | | 公開日 | 1995-11-14 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
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1DIU
 | | DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEX WITH BRODIMOPRIM-4,6-DICARBOXYLATE | | 分子名称: | BRODIMOPRIM-4,6-DICARBOXYLATE, DIHYDROFOLATE REDUCTASE | | 著者 | Morgan, W.D, Birdsall, B, Polshakov, V.I, Sali, D, Kompis, I, Feeney, J. | | 登録日 | 1995-08-01 | | 公開日 | 1995-11-14 | | 最終更新日 | 2022-02-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase.
Biochemistry, 34, 1995
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6Q44
 | | Est3 telomerase subunit in the yeast Hansenula polymorpha | | 分子名称: | Uncharacterized protein | | 著者 | Mantsyzov, A.B, Mariasina, S.S, Petrova, O.A, Efimov, S.V, Dontsova, O.A, Polshakov, V.I. | | 登録日 | 2018-12-05 | | 公開日 | 2019-12-25 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into the structure and function of Est3 from the Hansenula polymorpha telomerase.
Sci Rep, 10, 2020
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2KTV
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2KTU
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1HI7
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2MGT
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2LI9
 | | Metal binding domain of rat beta-amyloid | | 分子名称: | Amyloid beta A4 protein, ZINC ION | | 著者 | Polshakov, V, Istrate, A, Kozin, S, Makarov, A. | | 登録日 | 2011-08-25 | | 公開日 | 2012-01-18 | | 最終更新日 | 2012-03-21 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR solution structure of rat Abeta(1-16): toward understanding the mechanism of rats' resistance to Alzheimer's disease.
Biophys.J., 102, 2012
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7NF9
 | | N-terminal C2H2 Zn-finger domain of Clamp | | 分子名称: | Chromatin-linked adaptor for MSL proteins, isoform A, ZINC ION | | 著者 | Mariasina, S.S, Bonchuk, A.N, Tikhonova, E.A, Efimov, S.V, Maksimenko, O.G, Georgiev, P.G, Polshakov, V.I. | | 登録日 | 2021-02-05 | | 公開日 | 2021-12-29 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila.
Nucleic Acids Res., 50, 2022
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5NPT
 | | Structure of the N-terminal domain of the yeast telomerase reverse transcriptase | | 分子名称: | Telomerase reverse transcriptase | | 著者 | Rodina, E.V, Lebedev, A.A, Hakanpaa, J, Hackenberg, C, Petrova, O.A, Zvereva, M.I, Dontsova, O.A, Lamzin, V.S. | | 登録日 | 2017-04-18 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.
Nucleic Acids Res., 46, 2018
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2LF1
 | | Solution structure of L. casei dihydrofolate reductase complexed with NADPH, 30 structures | | 分子名称: | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Polshakov, V, Feeney, J, Birdsall, B, Kovalevskaya, N. | | 登録日 | 2011-06-28 | | 公開日 | 2011-12-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions
Biochemistry, 50, 2011
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