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4J4X
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BU of 4j4x by Molmil
Crystal structure of GraVN
Descriptor: NP protein
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-05-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4W
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BU of 4j4w by Molmil
Crystal structure of BueVN
Descriptor: Nucleocapsid
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-05-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.661 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4Y
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BU of 4j4y by Molmil
Triple mutant GraVN
Descriptor: NP protein
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-06-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4U
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BU of 4j4u by Molmil
Pentamer SFTSVN
Descriptor: Nucleocapsid protein
Authors:Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
Deposit date:2013-02-07
Release date:2013-05-22
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.803 Å)
Cite:Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
5JLY
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BU of 5jly by Molmil
Structure of Peroxiredoxin-1 from Schistosoma japonicum
Descriptor: Thioredoxin peroxidase-1
Authors:Wu, Q, Huang, F, Zeng, D, Liu, X, Zhao, J, Wang, H, Peng, Y, Li, P, Li, Y.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.051 Å)
Cite:Crystal structure of Peroxiredoxin-1 from Schistosoma japonicum
To Be Published
4TOT
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BU of 4tot by Molmil
Crystal structure of rat cyclophilin D in complex with a potent nonimmunosuppressive inhibitor
Descriptor: HEXAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, ...
Authors:Knapp, M.S, Elling, R.A.
Deposit date:2014-06-06
Release date:2014-11-12
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.39 Å)
Cite:Potent nonimmunosuppressive cyclophilin inhibitors with improved pharmaceutical properties and decreased transporter inhibition.
J.Med.Chem., 57, 2014
7XOE
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BU of 7xoe by Molmil
Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Prefusion state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide
Authors:Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J.
Deposit date:2022-05-01
Release date:2024-02-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
7XOG
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BU of 7xog by Molmil
Cryo-EM structure of S glycoprotein encoded by the Covid-19 mRNA vaccine candidate RQ3013 (Postfusion state)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein,peptide, ...
Authors:Wu, Z, Yu, Z, Tan, S, Lu, J, Lu, G, Lin, J.
Deposit date:2022-05-01
Release date:2024-03-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Preclinical evaluation of RQ3013, a broad-spectrum mRNA vaccine against SARS-CoV-2 variants.
Sci Bull (Beijing), 68, 2023
5GRL
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BU of 5grl by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ISOCITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
Authors:Ma, T, Ding, J.
Deposit date:2016-08-11
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5GRF
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BU of 5grf by Molmil
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
Authors:Ma, T, Ding, J.
Deposit date:2016-08-11
Release date:2017-02-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
4FZ7
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BU of 4fz7 by Molmil
Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide
Descriptor: 6-{[(1R,2S)-2-aminocyclohexyl]amino}-4-[(6-ethylpyridin-2-yl)amino]pyridazine-3-carboxamide, Tyrosine-protein kinase SYK
Authors:Kuglstatter, A, Slade, M.
Deposit date:2012-07-06
Release date:2013-07-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
J. Med. Chem., 57, 2014
5YOC
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BU of 5yoc by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond C102-R125C
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOG
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BU of 5yog by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond N14C-C93
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL, ...
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO4
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BU of 5yo4 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond K27C-A79C
Descriptor: Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-03-14
Last modified:2018-07-11
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO5
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BU of 5yo5 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond A20C-Q25C
Descriptor: Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOE
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BU of 5yoe by Molmil
Crystal Structure of flavodoxin with engineered disulfide bond A43C-L74C
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YM7
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BU of 5ym7 by Molmil
Crystal Structure of B562RIL without disulfide bond
Descriptor: Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-21
Release date:2017-11-22
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.56225181 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO6
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BU of 5yo6 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond T9C-A36C
Descriptor: Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-03-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.204 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YO3
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BU of 5yo3 by Molmil
Crystal Structure of B562RIL with engineered disulfide bond V16C-A29C
Descriptor: SULFATE ION, Soluble cytochrome b562
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-26
Release date:2018-05-09
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
5YOB
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BU of 5yob by Molmil
Crystal Structure of flavodoxin without engineered disulfide bond
Descriptor: FLAVIN MONONUCLEOTIDE, Flavodoxin, GLYCEROL
Authors:Pu, M, Xu, Z, Song, G, Liu, Z.J.
Deposit date:2017-10-27
Release date:2017-12-27
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.142 Å)
Cite:Protein crystal quality oriented disulfide bond engineering.
Protein Cell, 9, 2018
6KK1
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BU of 6kk1 by Molmil
Structure of thermal-stabilised(M8) human GLP-1 receptor transmembrane domain
Descriptor: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Authors:Song, G.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
6KJV
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BU of 6kjv by Molmil
Structure of thermal-stabilised(M9) human GLP-1 receptor transmembrane domain
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Authors:Song, G.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
6KK7
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BU of 6kk7 by Molmil
Structure of thermal-stabilised(M6) human GLP-1 receptor transmembrane domain
Descriptor: Glucagon-like peptide 1 receptor,Endolysin,Glucagon-like peptide 1 receptor, N-{4-[(R)-(3,3-dimethylcyclobutyl)({6-[4-(trifluoromethyl)-1H-imidazol-1-yl]pyridin-3-yl}amino)methyl]benzene-1-carbonyl}-beta-alanine
Authors:Song, G.
Deposit date:2019-07-23
Release date:2019-11-13
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Mutagenesis facilitated crystallization of GLP-1R.
Iucrj, 6, 2019
7CJF
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BU of 7cjf by Molmil
Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody heavy chain, ...
Authors:Guo, Y, Li, X, Zhang, G, Fu, D, Schweizer, L, Zhang, H, Rao, Z.
Deposit date:2020-07-10
Release date:2020-11-11
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.108 Å)
Cite:A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes.
Nat Commun, 12, 2021
7E9Q
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BU of 7e9q by Molmil
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab(1 out RBD, state3)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ...
Authors:Wang, X.F, Zhu, Y.Q.
Deposit date:2021-03-04
Release date:2022-03-09
Last modified:2022-09-21
Method:ELECTRON MICROSCOPY (3.65 Å)
Cite:A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD
Signal Transduct Target Ther, 7, 2022

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