3A3E
| Crystal structure of penicillin binding protein 4 (dacB) from Haemophilus influenzae, complexed with novel beta-lactam (CMV) | Descriptor: | (2R,4S)-2-[(1R)-1-({(2R)-2-[(4-ethyl-2,3-dioxopiperazin-1-yl)amino]-2-phenylacetyl}amino)-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Penicillin-binding protein 4 | Authors: | Kawai, F, Roper, D.I, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2009-06-12 | Release date: | 2009-12-22 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structures of penicillin-binding proteins 4 and 5 from Haemophilus influenzae J.Mol.Biol., 396, 2010
|
|
3AK5
| |
1IT3
| Hagfish CO ligand hemoglobin | Descriptor: | CARBON MONOXIDE, PROTOPORPHYRIN IX CONTAINING FE, hemoglobin | Authors: | Mito, M, Chong, K.T, Park, S.-Y, Tame, J.R. | Deposit date: | 2002-01-05 | Release date: | 2002-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structures of deoxy- and carbonmonoxyhemoglobin F1 from the hagfish Eptatretus burgeri J.Biol.Chem., 277, 2002
|
|
1J40
| Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe-CO) hemoglobin (laser unphotolysed) | Descriptor: | BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ... | Authors: | Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-02-21 | Release date: | 2003-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Direct observation of photolysis-induced tertiary structural changes in hemoglobin Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1J41
| Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Ni)-beta(Fe) hemoglobin (laser photolysed) | Descriptor: | BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ... | Authors: | Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-02-21 | Release date: | 2003-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Direct observation of photolysis-induced tertiary structural changes in hemoglobin Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1IUJ
| The structure of TT1380 protein from thermus thermophilus | Descriptor: | ZINC ION, hypothetical protein TT1380 | Authors: | Wada, T, Shirouzu, M, Park, S.-Y, Tame, J.R.H, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-05 | Release date: | 2003-09-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the conserved hypothetical protein TT1380 from Thermus thermophilus HB8 Proteins, 55, 2004
|
|
1J3Z
| Direct observation of photolysis-induced tertiary structural changes in human haemoglobin; Crystal structure of alpha(Fe-CO)-beta(Ni) hemoglobin (laser unphotolysed) | Descriptor: | BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ... | Authors: | Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-02-21 | Release date: | 2003-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Direct observation of photolysis-induced tertiary structural changes in hemoglobin Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1IWH
| Crystal Structure of Horse Carbonmonoxyhemoglobin-Bezafibrate Complex at 1.55A Resolution: A Novel Allosteric Binding Site in R-State Hemoglobin | Descriptor: | 2-[P-[2-P-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPIONIC ACID, CARBON MONOXIDE, Hemoglobin alpha chain, ... | Authors: | Shibayama, N, Miura, S, Tame, J.R.H, Yonetani, T, Park, S.-Y. | Deposit date: | 2002-05-15 | Release date: | 2002-10-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal Structure of Horse Carbonmonoxyhemoglobin-Bezafibrate Complex at 1.55A Resolution. A Novel Allosteric Binding Site in R-State Hemoglobin J.BIOL.CHEM., 277, 2002
|
|
1IT2
| Hagfish deoxy hemoglobin | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, hemoglobin | Authors: | Mito, M, Chong, K.T, Park, S.-Y, Tame, J.R. | Deposit date: | 2002-01-05 | Release date: | 2002-01-23 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structures of deoxy- and carbonmonoxyhemoglobin F1 from the hagfish Eptatretus burgeri J.Biol.Chem., 277, 2002
|
|
1J3Y
| Direct observation of photolysis-induced tertiary structural changes in human hemoglobin; Crystal structure of alpha(Fe)-beta(Ni) hemoglobin (laser photolysed) | Descriptor: | BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin alpha Chain, ... | Authors: | Adachi, S, Park, S.-Y, Tame, J.R.H, Shiro, Y, Shibayama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-02-21 | Release date: | 2003-07-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Direct observation of photolysis-induced tertiary structural changes in hemoglobin Proc.Natl.Acad.Sci.USA, 100, 2003
|
|
1QSH
| MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME | Descriptor: | PROTEIN (HEMOGLOBIN ALPHA CHAIN), PROTEIN (HEMOGLOBIN BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Miyazaki, G, Morimoto, H, Yun, K.-M, Park, S.-Y, Nakagawa, A, Minagawa, H, Shibayama, N. | Deposit date: | 1999-06-22 | Release date: | 1999-07-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Magnesium(II) and zinc(II)-protoporphyrin IX's stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme. J.Mol.Biol., 292, 1999
|
|
1QSI
| MAGNESIUM(II)-AND ZINC(II)-PROTOPORPHYRIN IX'S STABILIZE THE LOWEST OXYGEN AFFINITY STATE OF HUMAN HEMOGLOBIN EVEN MORE STRONGLY THAN DEOXYHEME | Descriptor: | CARBON MONOXIDE, PROTEIN (HEMOGLOBIN ALPHA CHAIN), PROTEIN (HEMOGLOBIN BETA CHAIN), ... | Authors: | Miyazaki, G, Morimoto, H, Yun, K.-M, Park, S.-Y, Nakagawa, A, Minagawa, H, Shibayama, N. | Deposit date: | 1999-06-22 | Release date: | 1999-07-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Magnesium(II) and zinc(II)-protoporphyrin IX's stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme. J.Mol.Biol., 292, 1999
|
|
1UDT
| Crystal structure of Human Phosphodiesterase 5 complexed with Sildenafil(Viagra) | Descriptor: | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, ZINC ION, ... | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | Deposit date: | 2003-05-06 | Release date: | 2004-05-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules Nature, 425, 2003
|
|
1UDU
| Crystal structure of Human Phosphodiesterase 5 complexed with tadalafil(Cialis) | Descriptor: | 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE, MAGNESIUM ION, ZINC ION, ... | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | Deposit date: | 2003-05-06 | Release date: | 2004-05-11 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.83 Å) | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules Nature, 425, 2003
|
|
1UHO
| Crystal structure of Human Phosphodiesterase 5 complexed with Vardenafil(Levitra) | Descriptor: | 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE, MAGNESIUM ION, ZINC ION, ... | Authors: | Sung, B.-J, Lee, J.I, Heo, Y.-S, Kim, J.H, Moon, J, Yoon, J.M, Hyun, Y.-L, Kim, E, Eum, S.J, Lee, T.G, Cho, J.M, Park, S.-Y, Lee, J.-O, Jeon, Y.H, Hwang, K.Y, Ro, S. | Deposit date: | 2003-07-09 | Release date: | 2004-07-09 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules Nature, 425, 2003
|
|
1UKH
| Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 | Descriptor: | 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1, Mitogen-activated protein kinase 8 isoform 4 | Authors: | Heo, Y.-S, Kim, Y.K, Sung, B.-J, Lee, H.S, Lee, J.I, Seo, C.I, Park, S.-Y, Kim, J.H, Hyun, Y.-L, Jeon, Y.H, Ro, S, Lee, T.G, Cho, J.M, Hwang, K.Y, Yang, C.-H. | Deposit date: | 2003-08-23 | Release date: | 2004-08-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 Embo J., 23, 2004
|
|
1UKI
| Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 | Descriptor: | 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1, 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, mitogen-activated protein kinase 8 isoform 4 | Authors: | Heo, Y.-S, Kim, Y.K, Sung, B.-J, Lee, H.S, Lee, J.I, Seo, C.I, Park, S.-Y, Kim, J.H, Hyun, Y.-L, Jeon, Y.H, Ro, S, Lee, T.G, Cho, J.M, Hwang, K.Y, Yang, C.-H. | Deposit date: | 2003-08-23 | Release date: | 2004-08-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125 Embo J., 23, 2004
|
|
1VCF
| Crystal Structure of IPP isomerase at I422 | Descriptor: | CADMIUM ION, FLAVIN MONONUCLEOTIDE, isopentenyl-diphosphate delta-isomerase | Authors: | Wada, T, Park, S.-Y, Tame, R.H, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-08 | Release date: | 2005-04-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structure of IPP isomerase at I422 To be Published
|
|
1VCG
| Crystal Structure of IPP isomerase at P43212 | Descriptor: | FLAVIN MONONUCLEOTIDE, isopentenyl-diphosphate delta-isomerase | Authors: | Wada, T, Park, S.-Y, Tame, R.H, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-03-08 | Release date: | 2005-04-19 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Crystal Structure of IPP isomerase at P43212 To be Published
|
|
1V9F
| Crystal structure of catalytic domain of pseudouridine synthase RluD from Escherichia coli | Descriptor: | PHOSPHATE ION, Ribosomal large subunit pseudouridine synthase D | Authors: | Mizutani, K, Machida, Y, Unzai, S, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2004-01-26 | Release date: | 2004-05-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli Biochemistry, 43, 2004
|
|
1V9K
| The crystal structure of the catalytic domain of pseudouridine synthase RluC from Escherichia coli | Descriptor: | Ribosomal large subunit pseudouridine synthase C, SULFATE ION | Authors: | Machida, Y, Mizutani, K, Unzai, S, Park, S.-Y, Tame, J.R.H. | Deposit date: | 2004-01-26 | Release date: | 2004-05-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the catalytic domains of pseudouridine synthases RluC and RluD from Escherichia coli Biochemistry, 43, 2004
|
|
1GEJ
| STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM | Descriptor: | CYTOCHROME P450 55A1, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y. | Deposit date: | 2000-11-13 | Release date: | 2000-12-06 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam. Biochemistry, 40, 2001
|
|
1GEI
| STRUCTURAL CHARACTERIZATION OF N-BUTYL-ISOCYANIDE COMPLEXES OF CYTOCHROMES P450NOR AND P450CAM | Descriptor: | CYTOCHROME P450 55A1, N-BUTYL ISOCYANIDE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Lee, D.-S, Park, S.-Y, Yamane, K, Shiro, Y. | Deposit date: | 2000-11-13 | Release date: | 2000-11-29 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural characterization of n-butyl-isocyanide complexes of cytochromes P450nor and P450cam. Biochemistry, 40, 2001
|
|
1EW0
| CRYSTAL STRUCTURE ANALYSIS OF THE SENSOR DOMAIN OF RMFIXL(FERROUS FORM) | Descriptor: | FIXL, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Miyatake, H, Mukai, M, Park, S.-Y, Adachi, S, Tamura, K, Nakamura, H, Nakamura, K, Tsuchiya, T, Iizuka, T, Shiro, Y. | Deposit date: | 2000-04-21 | Release date: | 2000-05-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Sensory mechanism of oxygen sensor FixL from Rhizobium meliloti: crystallographic, mutagenesis and resonance Raman spectroscopic studies J.MOL.BIOL., 301, 2000
|
|
1GED
| A positive charge route for the access of nadh to heme formed in the distal heme pocket of cytochrome p450nor | Descriptor: | BROMIDE ION, CYTOCHROME P450 55A1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Kudo, T, Takaya, N, Park, S.-Y, Shiro, Y, Shoun, H. | Deposit date: | 2000-11-02 | Release date: | 2000-11-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH J.Biol.Chem., 276, 2001
|
|