7AXZ
 
 | | Ku70/80 complex apo form | | 分子名称: | X-ray repair cross-complementing protein 5, X-ray repair cross-complementing protein 6 | | 著者 | Hnizda, A, Tesina, P, Novak, P, Blundell, T.L. | | 登録日 | 2020-11-10 | | 公開日 | 2021-02-10 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | SAP domain forms a flexible part of DNA aperture in Ku70/80.
Febs J., 288, 2021
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2G98
 | | human gamma-D-crystallin | | 分子名称: | Gamma crystallin D | | 著者 | Kmoch, S, Brynda, J, Awsav, B, Bezouska, K, Novak, P, Rezacova, P. | | 登録日 | 2006-03-06 | | 公開日 | 2006-05-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Link between a novel human gamma-D-crystallin allele and a unique cataract phenotype explained by protein crystallography.
Hum.Mol.Genet., 12, 2000
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2JNT
 | | Structure of Bombyx mori Chemosensory Protein 1 in Solution | | 分子名称: | Chemosensory protein CSP1 | | 著者 | Jansen, S, Zidek, L, Chmelik, J, Novak, P, Padrta, P, Picimbon, J, Lofstedt, C, Sklenar, V. | | 登録日 | 2007-02-02 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of Bombyx mori chemosensory protein 1 in solution
Arch.Insect Biochem.Physiol., 66, 2007
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2M94
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2MTI
 | | NMR structure of the lymphocyte receptor NKR-P1A | | 分子名称: | Killer cell lectin-like receptor subfamily B member 1A | | 著者 | Chmelik, J, Rozbesky, D, Pospisilova, E, Adamek, D, Novak, P. | | 登録日 | 2014-08-19 | | 公開日 | 2015-11-11 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the lymphocyte receptor Nkrp1a reveals a distinct conformation of the long loop region as compared to in the crystal structure.
Proteins, 84, 2016
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2NAN
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3RS1
 | | Mouse C-type lectin-related protein Clrg | | 分子名称: | C-type lectin domain family 2 member I, CHLORIDE ION | | 著者 | Skalova, T, Dohnalek, J, Duskova, J, Stepankova, A, Koval, T, Hasek, J, Kotynkova, K, Vanek, O, Bezouska, K. | | 登録日 | 2011-05-02 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Mouse Clr-g, a Ligand for NK Cell Activation Receptor NKR-P1F: Crystal Structure and Biophysical Properties.
J.Immunol., 189, 2012
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5YI9
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6TVM
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6TRJ
 | | LEDGF/p75 IBD dimer | | 分子名称: | PC4 and SFRS1-interacting protein | | 著者 | Kugler, M, Brynda, J. | | 登録日 | 2019-12-19 | | 公開日 | 2020-09-09 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Fine-tuning of the LEDGF/p75 interaction network by dimerization
Structure
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5EDF
 | | Crystal structure of the selenomethionine-substituted iron-regulated protein FrpD from Neisseria meningitidis | | 分子名称: | AZIDE ION, FrpC operon protein, HEXAETHYLENE GLYCOL, ... | | 著者 | Sviridova, E, Bumba, L, Rezacova, P, Sebo, P, Kuta Smatanova, I. | | 登録日 | 2015-10-21 | | 公開日 | 2017-02-01 | | 最終更新日 | 2017-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.
Sci Rep, 7, 2017
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5EDJ
 | | Crystal structure of the Neisseria meningitidis iron-regulated outer membrane lipoprotein FrpD | | 分子名称: | FrpC operon protein | | 著者 | Sviridova, E, Bumba, L, Rezacova, P, Sebo, P, Kuta Smatanova, I. | | 登録日 | 2015-10-21 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis.
Sci Rep, 7, 2017
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8CBN
 | | structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome | | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | 著者 | Koutna, E, Kouba, T, Novacek, J, Veverka, V. | | 登録日 | 2023-01-25 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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8CBQ
 | | structure of LEDGF/p75 PWWP domain bound to the H3K36 trimethylated dinucleosome | | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | 著者 | Koutna, E, Kouba, T, Novacek, J, Veverka, V. | | 登録日 | 2023-01-25 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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3CCK
 | | Human CD69 | | 分子名称: | CHLORIDE ION, Early activation antigen CD69 | | 著者 | Brynda, J, Vanek, O, Rezacova, P. | | 登録日 | 2008-02-26 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice
Febs J., 275, 2008
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8R6T
 | | NMR solution structure of thyropin IrThy-Cd from the hard tick Ixodes ricinus | | 分子名称: | Putative two thyropin protein (Fragment) | | 著者 | Srb, P, Veverka, V, Matouskova, Z, Orsaghova, K, Mares, M. | | 登録日 | 2023-11-23 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-03-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An Unusual Two-Domain Thyropin from Tick Saliva: NMR Solution Structure and Highly Selective Inhibition of Cysteine Cathepsins Modulated by Glycosaminoglycans.
Int J Mol Sci, 25, 2024
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8PEP
 | | H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 | | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | 著者 | Koutna, E, Kouba, T, Veverka, V. | | 登録日 | 2023-06-14 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | | 主引用文献 | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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8PC6
 | | H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex - pose 2 | | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | 著者 | Koutna, E, Kouba, T, Veverka, V. | | 登録日 | 2023-06-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | | 主引用文献 | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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8PEO
 | | H3K36me2 nucleosome-LEDGF/p75 PWWP domain complex | | 分子名称: | (2R)-2-amino-3-(2-dimethylaminoethylsulfanyl)propanoic acid, Histone H2A, Histone H2B 1.1, ... | | 著者 | Koutna, E, Kouba, T, Veverka, V. | | 登録日 | 2023-06-14 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | | 主引用文献 | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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8PC5
 | | H3K36me3 nucleosome-LEDGF/p75 PWWP domain complex | | 分子名称: | Histone H2A, Histone H2B 1.1, Histone H3, ... | | 著者 | Koutna, E, Kouba, T, Veverka, V. | | 登録日 | 2023-06-09 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Multivalency of nucleosome recognition by LEDGF.
Nucleic Acids Res., 51, 2023
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3CPC
 | | Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor | | 分子名称: | 3-(2-aminoquinazolin-6-yl)-4-methyl-1-[3-(trifluoromethyl)phenyl]pyridin-2(1H)-one, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | | 登録日 | 2008-03-31 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit.
J.Med.Chem., 51, 2008
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3CP9
 | | Crystal structure of the VEGFR2 kinase domain in complex with a pyridone inhibitor | | 分子名称: | 3-(2-aminoquinazolin-6-yl)-1-(3,3-dimethylindolin-6-yl)-4-methylpyridin-2(1H)-one, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | | 登録日 | 2008-03-31 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit.
J.Med.Chem., 51, 2008
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3CPB
 | | Crystal structure of the VEGFR2 kinase domain in complex with a bisamide inhibitor | | 分子名称: | N'-(6-aminopyridin-3-yl)-N-(2-cyclopentylethyl)-4-methyl-benzene-1,3-dicarboxamide, Vascular endothelial growth factor receptor 2 | | 著者 | Whittington, D.A, Long, A.M, Rose, P, Gu, Y, Zhao, H. | | 登録日 | 2008-03-31 | | 公開日 | 2008-06-17 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit.
J.Med.Chem., 51, 2008
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6EMO
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6EMR
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