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8EAX
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BU of 8eax by Molmil
Octameric prenyltransferase domain of fusicoccadiene Synthase with C2 symmetry sans transiently associating cyclase domains
Descriptor: Fusicoccadiene synthase
Authors:Faylo, J.L, van Eeuwen, T, Christianson, D.W.
Deposit date:2022-08-29
Release date:2022-11-02
Last modified:2022-11-16
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Transient Prenyltransferase-Cyclase Association in Fusicoccadiene Synthase, an Assembly-Line Terpene Synthase.
Biochemistry, 61, 2022
7CFL
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BU of 7cfl by Molmil
X-ray structure of autolysin Acd24020 catalytic domain from Clostridium difficile
Descriptor: CITRATE ANION, Putative cell wall hydrolase phosphatase-associated protein
Authors:Kamitori, S, Tamai, E.
Deposit date:2020-06-26
Release date:2020-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural and biochemical characterizations of the novel autolysin Acd24020 from Clostridioides difficile and its full-function catalytic domain as a lytic enzyme.
Mol.Microbiol., 115, 2021
7WBT
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BU of 7wbt by Molmil
Crystal structure of bovine NLRP9
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 9
Authors:Kamitsukasa, Y, Shimizu, T, Ohto, U.
Deposit date:2021-12-17
Release date:2022-04-06
Last modified:2022-04-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function.
Febs Lett., 596, 2022
7WBU
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BU of 7wbu by Molmil
Cryo-EM structure of bovine NLRP9
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NACHT, LRR and PYD domains-containing protein 9
Authors:Kamitsukasa, Y, Shimizu, T, Ohto, U.
Deposit date:2021-12-17
Release date:2022-04-06
Last modified:2022-04-27
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:The structure of NLRP9 reveals a unique C-terminal region with putative regulatory function.
Febs Lett., 596, 2022
7XW8
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BU of 7xw8 by Molmil
Crystal structure of Lysine Specific Demethylase 1 (LSD1) with TAK-418 distomer, FAD-adduct
Descriptor: GLYCEROL, Lysine-specific histone demethylase 1A, MAGNESIUM ION, ...
Authors:Oki, H.
Deposit date:2022-05-26
Release date:2022-10-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Design, synthesis, and structure-activity relationship of TAK-418 and its derivatives as a novel series of LSD1 inhibitors with lowered risk of hematological side effects.
Eur.J.Med.Chem., 239, 2022
6MUP
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BU of 6mup by Molmil
CENP-A nucleosome bound by two copies of CENP-C(CD) and two copies CENP-N(NT)
Descriptor: Centromere protein C, Centromere protein N, DNA (147-MER), ...
Authors:Allu, P.K, Black, B.E.
Deposit date:2018-10-23
Release date:2019-07-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Human Core Centromeric Nucleosome Complex.
Curr.Biol., 29, 2019
6MUO
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BU of 6muo by Molmil
CENP-A nucleosome bound by two copies of CENP-C(CD) and one copy CENP-N(NT)
Descriptor: Centromere protein C, Centromere protein N, DNA/RNA (147-MER), ...
Authors:Allu, P.K, Black, B.E.
Deposit date:2018-10-23
Release date:2019-07-24
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structure of the Human Core Centromeric Nucleosome Complex.
Curr.Biol., 29, 2019
1YNN
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BU of 1ynn by Molmil
Taq RNA polymerase-rifampicin complex
Descriptor: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ...
Authors:Campbell, E.A, Pavlova, O, Zenkin, N, Leon, F, Irschik, H, Jansen, R, Severinov, K, Darst, S.A.
Deposit date:2005-01-24
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural, functional, and genetic analysis of sorangicin inhibition of bacterial RNA polymerase
Embo J., 24, 2005
7VTQ
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BU of 7vtq by Molmil
Cryo-EM structure of mouse NLRP3 (full-length) dodecamer
Descriptor: 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ...
Authors:Ohto, U, Shimizu, T.
Deposit date:2021-10-30
Release date:2022-03-09
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
6UHC
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BU of 6uhc by Molmil
CryoEM structure of human Arp2/3 complex with bound NPFs
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin-related protein 2, Actin-related protein 2/3 complex subunit 1B, ...
Authors:Zimmet, A, van Eeuwen, T, Dominguez, R.
Deposit date:2019-09-27
Release date:2020-07-01
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism.
Sci Adv, 6, 2020
7VTP
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BU of 7vtp by Molmil
Cryo-EM structure of PYD-deleted human NLRP3 hexamer
Descriptor: 1-[4-(2-oxidanylpropan-2-yl)furan-2-yl]sulfonyl-3-(1,2,3,5-tetrahydro-s-indacen-4-yl)urea, ADENOSINE-5'-DIPHOSPHATE, NACHT, ...
Authors:Ohto, U, Shimizu, T.
Deposit date:2021-10-30
Release date:2022-03-09
Last modified:2022-03-23
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structural basis for the oligomerization-mediated regulation of NLRP3 inflammasome activation.
Proc.Natl.Acad.Sci.USA, 119, 2022
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