1NYH
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![BU of 1nyh by Molmil](/molmil-images/mine/1nyh) | Crystal Structure of the Coiled-coil Dimerization Motif of Sir4 | Descriptor: | Regulatory protein SIR4 | Authors: | Chang, J.F, Hall, B.E, Tanny, J.C, Moazed, D, Filman, D, Ellenberger, T. | Deposit date: | 2003-02-12 | Release date: | 2003-06-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of the Coiled-coil Dimerization Motif of Sir4 and Its Interaction With Sir3 Structure, 11, 2003
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4JJN
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![BU of 4jjn by Molmil](/molmil-images/mine/4jjn) | Crystal structure of heterochromatin protein Sir3 in complex with a silenced yeast nucleosome | Descriptor: | DNA (146-MER), Histone H2A.2, Histone H2B.2, ... | Authors: | Wang, F, Li, G, Mohammed, A, Lu, C, Currie, M, Johnson, A, Moazed, D. | Deposit date: | 2013-03-08 | Release date: | 2013-05-15 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.09 Å) | Cite: | Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proc.Natl.Acad.Sci.USA, 110, 2013
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6BOX
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![BU of 6box by Molmil](/molmil-images/mine/6box) | Structure of the S. pombe Clr4 catalytic domain bound to SAH | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Currie, M.A, Moazed, D. | Deposit date: | 2017-11-21 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.412 Å) | Cite: | Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability. Nature, 560, 2018
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6BP4
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![BU of 6bp4 by Molmil](/molmil-images/mine/6bp4) | Structure of the S. pombe Clr4 catalytic domain bound to SAM | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-9 specific, S-ADENOSYLMETHIONINE, ... | Authors: | Currie, M.A, Moazed, D. | Deposit date: | 2017-11-21 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7701 Å) | Cite: | Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability. Nature, 560, 2018
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3D1D
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![BU of 3d1d by Molmil](/molmil-images/mine/3d1d) | Hexagonal crystal structure of Tas3 C-terminal alpha motif | Descriptor: | RNA-induced transcriptional silencing complex protein tas3 | Authors: | Li, H, Patel, D.J. | Deposit date: | 2008-05-05 | Release date: | 2009-04-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Mol.Cell, 34, 2009
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3D1B
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![BU of 3d1b by Molmil](/molmil-images/mine/3d1b) | Tetragonal crystal structure of Tas3 C-terminal alpha motif | Descriptor: | RNA-induced transcriptional silencing complex protein tas3 | Authors: | Li, H, Patel, D.J. | Deposit date: | 2008-05-05 | Release date: | 2009-04-21 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing. Mol.Cell, 34, 2009
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2HJH
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![BU of 2hjh by Molmil](/molmil-images/mine/2hjh) | Crystal Structure of the Sir2 deacetylase | Descriptor: | (2R,3R,4S,5R)-5-({[(R)-{[(R)-{[(2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHOXY}(HYDROXY)PHOSPHORYL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL ACETATE, NAD-dependent histone deacetylase SIR2, NICOTINAMIDE, ... | Authors: | Hall, B.E, Ellenberger, T.E. | Deposit date: | 2006-06-30 | Release date: | 2008-04-08 | Last modified: | 2017-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Autoregulation of the yeast Sir2 deacetylase by reaction and trapping of a pseudosubstrate motif in the active site To be Published
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