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4ECM
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BU of 4ecm by Molmil
2.3 Angstrom Crystal Structure of a Glucose-1-phosphate Thymidylyltransferase from Bacillus anthracis in Complex with Thymidine-5-diphospho-alpha-D-glucose and Pyrophosphate
Descriptor: 2'DEOXY-THYMIDINE-5'-DIPHOSPHO-ALPHA-D-GLUCOSE, Glucose-1-phosphate thymidylyltransferase, PYROPHOSPHATE 2-
Authors:Minasov, G, Kuhn, M, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-03-26
Release date:2012-04-04
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Bacillus anthracis dTDP-L-rhamnose-biosynthetic enzyme glucose-1-phosphate thymidylyltransferase (RfbA).
Acta Crystallogr F Struct Biol Commun, 73, 2017
5HM3
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BU of 5hm3 by Molmil
2.25 Angstrom Resolution Crystal Structure of Long-chain-fatty-acid-AMP Ligase FadD32 from Mycobacterium tuberculosis in complex with Inhibitor 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine
Descriptor: 5'-O-[(11-phenoxyundecanoyl)sulfamoyl]adenosine, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Minasov, G, Warwrzak, Z, Kuhn, M.L, Shuvalova, L, Flores, K.J, Wilson, D.J, Grimes, K.D, Aldrich, C.C, Anderson, W.A, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-01-15
Release date:2016-08-03
Last modified:2016-09-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis.
Acs Infect Dis., 2, 2016
5I82
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BU of 5i82 by Molmil
First Crystal Structure of E.coli Based Recombinant Diphtheria Toxin Mutant CRM197
Descriptor: Diphtheria toxin, GLYCEROL, SULFATE ION
Authors:Minasov, G, Shuvalova, L, Mishra, R.P.N, Goel, A, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2016-02-18
Release date:2016-03-02
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and immunological characterization of E. coli derived recombinant CRM 197 protein used as carrier in conjugate vaccines.
Biosci.Rep., 38, 2018
4K6A
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BU of 4k6a by Molmil
Revised Crystal Structure of apo-form of Triosephosphate Isomerase (tpiA) from Escherichia coli at 1.8 Angstrom Resolution.
Descriptor: SODIUM ION, Triosephosphate isomerase
Authors:Minasov, G, Kuhn, M, Halavaty, A, Shuvalova, L, Dubrovska, I, Winsor, J, Grimshaw, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-04-15
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
PLoS ONE, 9, 2014
4JID
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BU of 4jid by Molmil
Crystal structure of BaLdcB / VanY-like L,D-carboxypeptidase Zinc(II)-free
Descriptor: CHLORIDE ION, D-alanyl-D-alanine carboxypeptidase family protein
Authors:Minasov, G, Wawrzak, Z, Onopriyenko, O, Skarina, T, Shatsman, S, Peterson, S.N, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-03-05
Release date:2013-04-03
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition.
Structure, 22, 2014
4MBR
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BU of 4mbr by Molmil
3.65 Angstrom Crystal Structure of Serine-rich Repeat Protein (Srr2) from Streptococcus agalactiae
Descriptor: Serine-rich repeat protein 2
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Seo, H.S, Seepersaud, R, Doran, K.S, Iverson, T.M, Sullam, P.M, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-08-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.65 Å)
Cite:Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae.
J.Biol.Chem., 288, 2013
4MBO
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BU of 4mbo by Molmil
1.65 Angstrom Crystal Structure of Serine-rich Repeat Adhesion Glycoprotein (Srr1) from Streptococcus agalactiae
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BETA-MERCAPTOETHANOL, CALCIUM ION, ...
Authors:Minasov, G, Shuvalova, L, Dubrovska, I, Winsor, J, Seo, H.S, Seepersaud, R, Doran, K.S, Iverson, T.M, Sullam, P.M, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-08-19
Release date:2013-11-06
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Characterization of Fibrinogen Binding by Glycoproteins Srr1 and Srr2 of Streptococcus agalactiae.
J.Biol.Chem., 288, 2013
4Q7G
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BU of 4q7g by Molmil
1.7 Angstrom Crystal Structure of leukotoxin LukD from Staphylococcus aureus.
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Leucotoxin LukDv
Authors:Minasov, G, Nocadello, S, Shuvalova, L, Shatsman, S, Kwon, K, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-04-24
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.
Acta Crystallogr D Struct Biol, 72, 2016
7L5V
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BU of 7l5v by Molmil
Crystal Structure of the Class D Beta-lactamase OXA-935 from Pseudomonas aeruginosa, Monoclinic Crystal Form
Descriptor: Beta-lactamase
Authors:Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-23
Release date:2021-12-29
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family beta-Lactamase from Pseudomonas aeruginosa.
Antimicrob.Agents Chemother., 66, 2022
7L5R
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BU of 7l5r by Molmil
Crystal Structure of the Oxacillin-hydrolyzing Class D Extended-spectrum Beta-lactamase OXA-14 from Pseudomonas aeruginosa
Descriptor: Beta-lactamase, GLYCEROL, SULFATE ION
Authors:Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2020-12-22
Release date:2021-12-29
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family beta-Lactamase from Pseudomonas aeruginosa.
Antimicrob.Agents Chemother., 66, 2022
3OTR
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BU of 3otr by Molmil
2.75 Angstrom Crystal Structure of Enolase 1 from Toxoplasma gondii
Descriptor: CHLORIDE ION, Enolase, SULFATE ION
Authors:Minasov, G, Ruan, J, Shuvalova, L, Halavaty, A, Ngo, H, Tomavo, S, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-09-13
Release date:2010-09-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions.
Acta Crystallogr.,Sect.D, 71, 2015
3M7W
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BU of 3m7w by Molmil
Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in Covalent Complex with Dehydroquinate
Descriptor: 1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC ACID, 3-dehydroquinate dehydratase, GLYCEROL
Authors:Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-03-17
Release date:2010-04-07
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.
J.Biol.Chem., 286, 2011
3L2I
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BU of 3l2i by Molmil
1.85 Angstrom Crystal Structure of the 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2.
Descriptor: 3-dehydroquinate dehydratase, MAGNESIUM ION
Authors:Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-12-15
Release date:2009-12-29
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:A conserved surface loop in type I dehydroquinate dehydratases positions an active site arginine and functions in substrate binding.
Biochemistry, 50, 2011
3NNT
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BU of 3nnt by Molmil
Crystal Structure of K170M Mutant of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in Non-Covalent Complex with Dehydroquinate.
Descriptor: 1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC ACID, 3-dehydroquinate dehydratase
Authors:Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-06-24
Release date:2010-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.
J.Biol.Chem., 286, 2011
3OEX
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BU of 3oex by Molmil
Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium with close loop conformation.
Descriptor: 3-dehydroquinate dehydratase, CHLORIDE ION
Authors:Minasov, G, Light, S.H, Shuvalova, L, Papazisi, L, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-08-13
Release date:2010-09-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A conserved surface loop in type I dehydroquinate dehydratases positions an active site arginine and functions in substrate binding.
Biochemistry, 50, 2011
4NU7
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BU of 4nu7 by Molmil
2.05 Angstrom Crystal Structure of Ribulose-phosphate 3-epimerase from Toxoplasma gondii.
Descriptor: CHLORIDE ION, Ribulose-phosphate 3-epimerase, SULFATE ION, ...
Authors:Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-12-03
Release date:2013-12-18
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4O0N
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BU of 4o0n by Molmil
2.4 Angstrom Resolution Crystal Structure of Putative Nucleoside Diphosphate Kinase from Toxoplasma gondii.
Descriptor: Nucleoside diphosphate kinase, SULFATE ION
Authors:Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Shanmugam, D, Roos, D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-12-13
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4MVJ
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BU of 4mvj by Molmil
2.85 Angstrom Resolution Crystal Structure of Glyceraldehyde 3-phosphate Dehydrogenase A (gapA) from Escherichia coli Modified by Acetyl Phosphate.
Descriptor: ACETATE ION, ACETYLPHOSPHATE, CHLORIDE ION, ...
Authors:Minasov, G, Kuhn, M, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-09-24
Release date:2014-04-23
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
Plos One, 9, 2014
4ODI
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BU of 4odi by Molmil
2.6 Angstrom Crystal Structure of Putative Phosphoglycerate Mutase 1 from Toxoplasma gondii
Descriptor: Phosphoglycerate mutase PGMII, SODIUM ION
Authors:Minasov, G, Ruan, J, Ngo, H, Shuvalova, L, Dubrovska, I, Flores, K, Shanmugam, D, Roos, D, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-01-10
Release date:2014-01-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii .
Front Cell Infect Microbiol, 8, 2018
4MVA
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BU of 4mva by Molmil
1.43 Angstrom Resolution Crystal Structure of Triosephosphate Isomerase (tpiA) from Escherichia coli in Complex with Acetyl Phosphate.
Descriptor: 1,2-ETHANEDIOL, ACETYLPHOSPHATE, CHLORIDE ION, ...
Authors:Minasov, G, Kuhn, M.L, Dubrovska, I, Winsor, J, Shuvalova, L, Grimshaw, S, Kwon, K, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-09-23
Release date:2014-04-16
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
Plos One, 9, 2014
5JTH
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BU of 5jth by Molmil
Crystal structure of E67A calmodulin - CaM:RM20 analog complex
Descriptor: CALCIUM ION, Calmodulin, Myosin light chain kinase, ...
Authors:Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M.
Deposit date:2016-05-09
Release date:2017-07-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structure of E67A calmodulin - CaM:RM20 analog complex
To Be Published
5JQA
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BU of 5jqa by Molmil
CaM:RM20 complex
Descriptor: CALCIUM ION, Calmodulin, Myosin light chain kinase, ...
Authors:Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M.
Deposit date:2016-05-04
Release date:2017-10-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CaM:RM20 complex
To be Published
1LHY
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BU of 1lhy by Molmil
Crystal structure of TEM-30 beta-Lactamase at 2.0 Angstrom
Descriptor: Class A beta-Lactamase- TEM 30, PHOSPHATE ION
Authors:Wang, X, Minasov, G, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-09-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34.
J.Biol.Chem., 277, 2002
1LS1
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BU of 1ls1 by Molmil
T. aquaticus Ffh NG Domain at 1.1A Resolution
Descriptor: MAGNESIUM ION, OXYGEN MOLECULE, SIGNAL RECOGNITION PARTICLE PROTEIN
Authors:Ramirez, U.D, Minasov, G, Freymann, D.M.
Deposit date:2002-05-16
Release date:2002-11-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Basis for Mobility in the 1.1 A Crystal Structure of the NG Domain of Thermus aquaticus Ffh
J.Mol.Biol., 320, 2002
1LI9
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BU of 1li9 by Molmil
Crystal structure of TEM-34 beta-Lactamase at 1.5 Angstrom
Descriptor: Class A beta-Lactamase- TEM-34, PHOSPHATE ION, POTASSIUM ION
Authors:Wang, X, Minasov, G, Shoichet, B.K.
Deposit date:2002-04-17
Release date:2002-09-11
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:The structural bases of antibiotic resistance in the clinically derived mutant beta-lactamases TEM-30, TEM-32, and TEM-34.
J.Biol.Chem., 277, 2002

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