3M7W

Crystal Structure of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium LT2 in Covalent Complex with Dehydroquinate

Summary for 3M7W

• Entry DOI: 10.2210/pdb3m7w/pdb
• Related: 3L2I 3LB0
• Descriptor: 3-dehydroquinate dehydratase, 1,3,4-TRIHYDROXY-5-OXO-CYCLOHEXANECARBOXYLIC ACID, GLYCEROL, ... (4 entities in total)
• Functional Keywords: type i 3-dehydroquinase, dhqase_i, dehydroquinate, idp90922, amino-acid biosynthesis, aromatic amino acid biosynthesis, lyase, schiff base, center for structural genomics of infectious diseases, csgid
• Biological source: Salmonella enterica subsp. enterica serovar Typhimurium
• Total number of polymer chains: 6
• Total formula weight: 168208.13

Authors

Minasov, G.,Light, S.H.,Shuvalova, L.,Papazisi, L.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2010-03-17, release date: 2010-04-07, Last modification date: 2023-09-06)

• Primary citation: Light, S.H.,Minasov, G.,Shuvalova, L.,Duban, M.E.,Caffrey, M.,Anderson, W.F.,Lavie, A.; Insights into the mechanism of type I dehydroquinate dehydratases from structures of reaction intermediates.; J.Biol.Chem., 286:3531-3539, 2011; PubMed: 21087925; DOI: 10.1074/jbc.M110.192831

Experimental method

X-RAY DIFFRACTION (1.95 Å)