3LNN
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![BU of 3lnn by Molmil](/molmil-images/mine/3lnn) | Crystal structure of ZneB from Cupriavidus metallidurans | Descriptor: | Membrane fusion protein (MFP) heavy metal cation efflux ZneB (CzcB-like), ZINC ION | Authors: | Lee, J.K, De Angelis, F, Miercke, L.J, Stroud, R.M, Vandenbussche, G, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2010-02-02 | Release date: | 2010-06-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.796 Å) | Cite: | Metal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systems. Proc.Natl.Acad.Sci.USA, 107, 2010
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2BCE
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![BU of 2bce by Molmil](/molmil-images/mine/2bce) | CHOLESTEROL ESTERASE FROM BOS TAURUS | Descriptor: | CHOLESTEROL ESTERASE | Authors: | Chen, J.C.-H, Miercke, L.J.W, Krucinski, J, Starr, J.R, Saenz, G, Wang, X, Spilburg, C.A, Lange, L.G, Ellsworth, J.L, Stroud, R.M. | Deposit date: | 1998-01-28 | Release date: | 1999-02-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structure of bovine pancreatic cholesterol esterase at 1.6 A: novel structural features involved in lipase activation. Biochemistry, 37, 1998
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1Y4C
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![BU of 1y4c by Molmil](/molmil-images/mine/1y4c) | Designed Helical Protein fusion MBP | Descriptor: | Maltose binding protein fused with designed helical protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | LaPorte, S.L, Forsyth, C.M, Cunningham, B.C, Miercke, L.J, Akhavan, D, Stroud, R.M. | Deposit date: | 2004-11-30 | Release date: | 2005-02-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | De novo design of an IL-4 antagonist and its structure at 1.9 A. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1EXQ
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![BU of 1exq by Molmil](/molmil-images/mine/1exq) | CRYSTAL STRUCTURE OF THE HIV-1 INTEGRASE CATALYTIC CORE DOMAIN | Descriptor: | CADMIUM ION, CHLORIDE ION, POL POLYPROTEIN, ... | Authors: | Chen, J.C.-H, Krucinski, J, Miercke, L.J.W, Finer-Moore, J.S, Tang, A.H, Leavitt, A.D, Stroud, R.M. | Deposit date: | 2000-05-03 | Release date: | 2000-11-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding. Proc.Natl.Acad.Sci.USA, 97, 2000
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1EX4
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![BU of 1ex4 by Molmil](/molmil-images/mine/1ex4) | HIV-1 INTEGRASE CATALYTIC CORE AND C-TERMINAL DOMAIN | Descriptor: | 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, INTEGRASE | Authors: | Chen, J.C.-H, Krucinski, J, Miercke, L.J.W, Finer-Moore, J.S, Tang, A.H, Leavitt, A.D, Stroud, R.M. | Deposit date: | 2000-04-28 | Release date: | 2000-06-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: a model for viral DNA binding. Proc.Natl.Acad.Sci.USA, 97, 2000
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1FX8
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![BU of 1fx8 by Molmil](/molmil-images/mine/1fx8) | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITH SUBSTRATE GLYCEROL | Descriptor: | GLYCEROL, GLYCEROL UPTAKE FACILITATOR PROTEIN, octyl beta-D-glucopyranoside | Authors: | Fu, D, Libson, A, Miercke, L.J.W, Weitzman, C, Nollert, P, Stroud, R.M. | Deposit date: | 2000-09-25 | Release date: | 2000-11-01 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of a glycerol-conducting channel and the basis for its selectivity. Science, 290, 2000
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4HB1
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![BU of 4hb1 by Molmil](/molmil-images/mine/4hb1) | A DESIGNED FOUR HELIX BUNDLE PROTEIN. | Descriptor: | DHP1, UNKNOWN ATOM OR ION | Authors: | Schafmeister, C.E, Laporte, S.L, Miercke, L.J.W, Stroud, R.M. | Deposit date: | 1997-11-10 | Release date: | 1998-03-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A designed four helix bundle protein with native-like structure. Nat.Struct.Biol., 4, 1997
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1LDF
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![BU of 1ldf by Molmil](/molmil-images/mine/1ldf) | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) MUTATION W48F, F200T | Descriptor: | GLYCEROL, Glycerol uptake facilitator protein, MAGNESIUM ION, ... | Authors: | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | Deposit date: | 2002-04-08 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science, 296, 2002
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1LDA
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![BU of 1lda by Molmil](/molmil-images/mine/1lda) | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL | Descriptor: | Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside | Authors: | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | Deposit date: | 2002-04-08 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science, 296, 2002
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1LDI
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![BU of 1ldi by Molmil](/molmil-images/mine/1ldi) | CRYSTAL STRUCTURE OF THE E. COLI GLYCEROL FACILITATOR (GLPF) WITHOUT SUBSTRATE GLYCEROL | Descriptor: | Glycerol uptake facilitator protein, octyl beta-D-glucopyranoside | Authors: | Nollert, P, Miercke, L.J.W, O'Connell, J, Stroud, R.M. | Deposit date: | 2002-04-08 | Release date: | 2002-05-08 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science, 296, 2002
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1MZJ
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![BU of 1mzj by Molmil](/molmil-images/mine/1mzj) | Crystal Structure of the Priming beta-Ketosynthase from the R1128 Polyketide Biosynthetic Pathway | Descriptor: | ACETYL GROUP, Beta-ketoacylsynthase III, COENZYME A | Authors: | Pan, H, Tsai, S.C, Meadows, E.S, Miercke, L.J.W, Keatinge-Clay, A, O'Connell, J, Khosla, C, Stroud, R.M. | Deposit date: | 2002-10-08 | Release date: | 2002-12-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of the priming beta-ketosynthase from the
R1128 polyketide biosynthetic pathway Structure, 10
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1NN6
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![BU of 1nn6 by Molmil](/molmil-images/mine/1nn6) | Human Pro-Chymase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chymase | Authors: | Reiling, K.K, Krucinski, J, Miercke, L.J.W, Raymond, W.W, Caughey, G.H, Stroud, R.M. | Deposit date: | 2003-01-12 | Release date: | 2003-03-04 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Structure of human pro-chymase: a model for the activating transition of granule-associated proteases. Biochemistry, 42, 2003
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3GD8
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![BU of 3gd8 by Molmil](/molmil-images/mine/3gd8) | Crystal Structure of Human Aquaporin 4 at 1.8 and its Mechanism of Conductance | Descriptor: | Aquaporin-4, GLYCEROL, octyl beta-D-glucopyranoside | Authors: | Ho, J.D, Yeh, R, Sandstrom, A, Chorny, I, Harries, W.E.C, Robbins, R.A, Miercke, L.J.W, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP) | Deposit date: | 2009-02-23 | Release date: | 2009-03-31 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance. Proc.Natl.Acad.Sci.USA, 106, 2009
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1KEZ
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![BU of 1kez by Molmil](/molmil-images/mine/1kez) | Crystal Structure of the Macrocycle-forming Thioesterase Domain of Erythromycin Polyketide Synthase (DEBS TE) | Descriptor: | ERYTHRONOLIDE SYNTHASE | Authors: | Tsai, S.-C, Miercke, L.J.W, Krucinski, J, Gokhale, R, Chen, J.C.-H, Foster, P.G, Cane, D.E, Khosla, C, Stroud, R.M. | Deposit date: | 2001-11-19 | Release date: | 2002-01-09 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the macrocycle-forming thioesterase domain of the erythromycin polyketide synthase: versatility from a unique substrate channel. Proc.Natl.Acad.Sci.USA, 98, 2001
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1YMG
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![BU of 1ymg by Molmil](/molmil-images/mine/1ymg) | The Channel Architecture of Aquaporin O at 2.2 Angstrom Resolution | Descriptor: | Lens fiber major intrinsic protein, nonyl beta-D-glucopyranoside | Authors: | Harries, W.E.C, Akhavan, D, Miercke, L.J.W, Khademi, S, Stroud, R.M. | Deposit date: | 2005-01-20 | Release date: | 2005-02-08 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | The Channel Architecture of Aquaporin 0 at a 2.2-A Resolution Proc.Natl.Acad.Sci.USA, 101, 2004
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1NM2
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![BU of 1nm2 by Molmil](/molmil-images/mine/1nm2) | Malonyl-CoA:ACP Transacylase | Descriptor: | ACETIC ACID, NICKEL (II) ION, malonyl CoA:acyl carrier protein malonyltransferase | Authors: | Keatinge-Clay, A.T, Shelat, A.A, Savage, D.F, Tsai, S, Miercke, L.J.W, O'Connell III, J.D, Khosla, C, Stroud, R.M. | Deposit date: | 2003-01-08 | Release date: | 2003-01-21 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Catalysis, Specificity, and ACP Docking Site of
Streptomyces coelicolor Malonyl-CoA:ACP Transacylase Structure, 11, 2003
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1U7C
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![BU of 1u7c by Molmil](/molmil-images/mine/1u7c) | Crystal Structure of AmtB from E.Coli with Methyl Ammonium. | Descriptor: | METHYLAMINE, Probable ammonium transporter | Authors: | Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M. | Deposit date: | 2004-08-03 | Release date: | 2004-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A Science, 305, 2004
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1U77
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![BU of 1u77 by Molmil](/molmil-images/mine/1u77) | Crystal Structure of Ammonia Channel AmtB from E. Coli | Descriptor: | Probable ammonium transporter | Authors: | Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M. | Deposit date: | 2004-08-02 | Release date: | 2004-09-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A Science, 305, 2004
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1U7G
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![BU of 1u7g by Molmil](/molmil-images/mine/1u7g) | Crystal Structure of Ammonia Channel AmtB from E. Coli | Descriptor: | AMMONIA, AMMONIUM ION, Probable ammonium transporter, ... | Authors: | Khademi, S, O'Connell III, J, Remis, J, Robles-Colmenares, Y, Miercke, L.J.W, Stroud, R.M. | Deposit date: | 2004-08-03 | Release date: | 2004-09-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mechanism of ammonia transport by Amt/MEP/Rh: structure of AmtB at 1.35 A Science, 305, 2004
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3C02
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![BU of 3c02 by Molmil](/molmil-images/mine/3c02) | |
3NKC
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![BU of 3nkc by Molmil](/molmil-images/mine/3nkc) | Crystal structure of AqpZ F43W,H174G,T183F | Descriptor: | Aquaporin Z, octyl beta-D-glucopyranoside | Authors: | Savage, D.F, O'Connell III, J.D, Finer-Moore, J, Stroud, R.M. | Deposit date: | 2010-06-18 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural context shapes the aquaporin selectivity filter. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NKA
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![BU of 3nka by Molmil](/molmil-images/mine/3nka) | Crystal structure of AqpZ H174G,T183F | Descriptor: | Aquaporin Z, GLYCEROL, octyl beta-D-glucopyranoside | Authors: | Savage, D.F, O'Connell III, J.D, Finer-Moore, J, Stroud, R.M. | Deposit date: | 2010-06-18 | Release date: | 2010-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural context shapes the aquaporin selectivity filter. Proc.Natl.Acad.Sci.USA, 107, 2010
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3NK5
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![BU of 3nk5 by Molmil](/molmil-images/mine/3nk5) | Crystal structure of AqpZ mutant F43W | Descriptor: | Aquaporin Z, octyl beta-D-glucopyranoside | Authors: | Savage, D.F, O'Connell, J.D, Stroud, R.M, Finer-Moore, J.S. | Deposit date: | 2010-06-18 | Release date: | 2010-08-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural context shapes the aquaporin selectivity filter. Proc.Natl.Acad.Sci.USA, 107, 2010
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2B6P
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![BU of 2b6p by Molmil](/molmil-images/mine/2b6p) | X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state | Descriptor: | Lens fiber major intrinsic protein | Authors: | Gonen, T, Cheng, Y, Sliz, P, Hiroaki, Y, Fujiyoshi, Y, Harrison, S.C, Walz, T. | Deposit date: | 2005-10-03 | Release date: | 2005-12-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Lipid-protein interactions in double-layered two-dimensional AQP0 crystals. Nature, 438, 2005
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