1NN6

Human Pro-Chymase

Summary for 1NN6

Related1KLT
DescriptorChymase, N-ACETYL-D-GLUCOSAMINE (3 entities in total)
Functional Keywordsserine protease, zymogen, chymase, conformational change, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationSecreted P23946
Total number of polymer chains1
Total molecular weight25916.76
Authors
Reiling, K.K.,Krucinski, J.,Miercke, L.J.W.,Raymond, W.W.,Caughey, G.H.,Stroud, R.M. (deposition date: 2003-01-12, release date: 2003-03-04, Last modification date: 2018-01-31)
Primary citation
Reiling, K.K.,Krucinski, J.,Miercke, L.J.,Raymond, W.W.,Caughey, G.H.,Stroud, R.M.
Structure of human pro-chymase: a model for the activating transition of granule-associated proteases.
Biochemistry, 42:2616-2624, 2003
PubMed: 12614156 (PDB entries with the same primary citation)
DOI: 10.1021/bi020594d
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.25650.5%1.7%13.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report