5D2N
 
 | | Crystal structure of C25-NLV-HLA-A2 complex | | 分子名称: | ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ... | | 著者 | Mariuzza, R.A, Yang, X. | | 登録日 | 2015-08-05 | | 公開日 | 2015-10-07 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | | 主引用文献 | Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
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1NBY
 | | Crystal Structure of HyHEL-63 complexed with HEL mutant K96A | | 分子名称: | Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain | | 著者 | Mariuzza, R.A, Li, Y, Urrutia, M, Smith-Gill, S.J. | | 登録日 | 2002-12-04 | | 公開日 | 2003-04-01 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen
Biochemistry, 42, 2003
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1NDG
 | | Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme | | 分子名称: | ACETIC ACID, Lysozyme C, antibody kappa light chain, ... | | 著者 | Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J. | | 登録日 | 2002-12-09 | | 公開日 | 2003-06-03 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
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1NBZ
 | | Crystal Structure of HyHEL-63 complexed with HEL mutant K97A | | 分子名称: | Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain | | 著者 | Mariuzza, R.A, Li, Y, Urrutia, M, Smith-Gill, S.J. | | 登録日 | 2002-12-04 | | 公開日 | 2003-04-01 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen
Biochemistry, 42, 2003
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1NDM
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5D2L
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4E42
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | 分子名称: | CHLORIDE ION, NITRATE ION, SODIUM ION, ... | | 著者 | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | 登録日 | 2012-03-11 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
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8GOP
 | | SARS-CoV-2 specific private TCR RLQ7 | | 分子名称: | SARS-CoV-2 specific private TCR RLQ7 alpha, SARS-CoV-2 specific private TCR RLQ7 beta | | 著者 | Wu, D, Mariuzza, R.A. | | 登録日 | 2022-08-25 | | 公開日 | 2023-03-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity.
J.Biol.Chem., 299, 2023
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8GOM
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8GON
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7R6J
 | | Co-crystal structure of Chaetomium glucosidase with compound 1 | | 分子名称: | (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[(3-{[3-methyl-5-(pyrimidin-2-yl)anilino]methyl}phenyl)methyl]piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Karade, S.S, Mariuzza, R.A. | | 登録日 | 2021-06-22 | | 公開日 | 2022-07-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | | 主引用文献 | Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity.
J.Med.Chem., 66, 2023
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3C8K
 | | The crystal structure of Ly49C bound to H-2Kb | | 分子名称: | H-2 class I histocompatibility antigen, K-B alpha chain, Natural killer cell receptor Ly-49C, ... | | 著者 | Deng, L, Mariuzza, R.A. | | 登録日 | 2008-02-12 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Molecular architecture of the major histocompatibility complex class I-binding site of Ly49 natural killer cell receptors.
J.Biol.Chem., 283, 2008
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8SO3
 | | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... | | 著者 | Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. | | 登録日 | 2023-04-28 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | | 主引用文献 | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
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8SR0
 | | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 local refined | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Lymphocyte activation gene 3 protein, favezelimab Fab heavy chain, ... | | 著者 | Mishra, A.K, Shahid, S, Karade, S.S, Mariuzza, R.A. | | 登録日 | 2023-05-05 | | 公開日 | 2023-09-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | ELECTRON MICROSCOPY (3.53 Å) | | 主引用文献 | CryoEM structure of a therapeutic antibody (favezelimab) bound to human LAG3 determined using a bivalent Fab as fiducial marker.
Structure, 31, 2023
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6WJU
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6WK4
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6WKL
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6WKM
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6X9X
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2PTT
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2PTU
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2PTV
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4XVJ
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1AC6
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1A2Y
 | | HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3 | | 分子名称: | IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ... | | 著者 | Tsuchiya, D, Mariuzza, R.A. | | 登録日 | 1998-01-13 | | 公開日 | 1998-04-29 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
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