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4KWW
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BU of 4kww by Molmil
The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid
分子名称: Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID
著者Malik, S.S, Dimeka, P.N, Ncube, Z, Toth, E.A.
登録日2013-05-24
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Proteins, 82, 2014
4KWV
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BU of 4kwv by Molmil
Crystal Structure of human apo-QPRT
分子名称: Nicotinate-nucleotide pyrophosphorylase [carboxylating]
著者Malik, S.S, Patterson, D.N, Ncube, Z, Toth, E.A.
登録日2013-05-24
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid.
Proteins, 82, 2014
5CYS
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BU of 5cys by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GcaC mismatch
分子名称: ACETIC ACID, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2015-07-30
公開日2015-09-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Characterizing the enzyme-product complexes of thymine DNA glycosylase using crystallography and NMR
Nucleic Acids Res., 2015
4XEG
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BU of 4xeg by Molmil
Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ...
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2014-12-23
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z47
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BU of 4z47 by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, DNA, ...
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2015-04-01
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z7B
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BU of 4z7b by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ...
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2015-04-07
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z3A
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BU of 4z3a by Molmil
Acetate-free structure of the enzyme-product complex resulting from TDG action on a GU mismatch
分子名称: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2015-03-31
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
4Z7Z
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BU of 4z7z by Molmil
Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base
分子名称: 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ...
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2015-04-08
公開日2015-09-16
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res., 43, 2015
5JXY
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BU of 5jxy by Molmil
Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog
分子名称: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
著者Pidugu, L.S, Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2016-05-13
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
5HF7
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BU of 5hf7 by Molmil
TDG enzyme-substrate complex
分子名称: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2016-01-06
公開日2016-09-28
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
5FF8
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BU of 5ff8 by Molmil
TDG enzyme-product complex
分子名称: DNA, G/T mismatch-specific thymine DNA glycosylase
著者Pozharski, E, Malik, S.S, Drohat, A.C.
登録日2015-12-18
公開日2016-09-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res., 44, 2016
6U17
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BU of 6u17 by Molmil
Human thymine DNA glycosylase bound to DNA with 2'-F-5-carboxyl-dC substrate analog
分子名称: ACETATE ION, DNA (28-MER), DNA (30-MER), ...
著者Pidugu, L.S, Pozharski, E, Drohat, A.C.
登録日2019-08-15
公開日2019-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J.Am.Chem.Soc., 141, 2019
6U15
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BU of 6u15 by Molmil
Human thymine DNA glycosylase N140A mutant bound to DNA with 2'-F-5-carboxyl-dC substrate analog
分子名称: DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
著者Pidugu, L.S, Pozharski, E, Drohat, A.C.
登録日2019-08-15
公開日2019-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J.Am.Chem.Soc., 141, 2019
6U16
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BU of 6u16 by Molmil
Human thymine DNA glycosylase N140A mutant bound to DNA with 5-carboxyl-dC substrate
分子名称: 1,2-ETHANEDIOL, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase
著者Pidugu, L.S, Pozharski, E, Drohat, A.C.
登録日2019-08-15
公開日2019-11-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J.Am.Chem.Soc., 141, 2019

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件を2024-05-01に公開中

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