4KWW
| The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid | 分子名称: | Nicotinate-nucleotide pyrophosphorylase [carboxylating], PHTHALIC ACID | 著者 | Malik, S.S, Dimeka, P.N, Ncube, Z, Toth, E.A. | 登録日 | 2013-05-24 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The crystal structure of human quinolinic acid phosphoribosyltransferase in complex with its inhibitor phthalic acid. Proteins, 82, 2014
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4KWV
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5CYS
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4XEG
| Structure of the enzyme-product complex resulting from TDG action on a G/hmU mismatch | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2014-12-23 | 公開日 | 2015-09-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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4Z47
| Structure of the enzyme-product complex resulting from TDG action on a GU mismatch in the presence of excess base | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA, ... | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2015-04-01 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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4Z7B
| Structure of the enzyme-product complex resulting from TDG action on a GfC mismatch | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2015-04-07 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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4Z3A
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4Z7Z
| Structure of the enzyme-product complex resulting from TDG action on a GT mismatch in the presence of excess base | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, DNA (28-MER), ... | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2015-04-08 | 公開日 | 2015-09-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA. Nucleic Acids Res., 43, 2015
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5JXY
| Enzyme-substrate complex of TDG catalytic domain bound to a G/U analog | 分子名称: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | 著者 | Pidugu, L.S, Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2016-05-13 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
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5HF7
| TDG enzyme-substrate complex | 分子名称: | DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2016-01-06 | 公開日 | 2016-09-28 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
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5FF8
| TDG enzyme-product complex | 分子名称: | DNA, G/T mismatch-specific thymine DNA glycosylase | 著者 | Pozharski, E, Malik, S.S, Drohat, A.C. | 登録日 | 2015-12-18 | 公開日 | 2016-09-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues. Nucleic Acids Res., 44, 2016
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6U17
| Human thymine DNA glycosylase bound to DNA with 2'-F-5-carboxyl-dC substrate analog | 分子名称: | ACETATE ION, DNA (28-MER), DNA (30-MER), ... | 著者 | Pidugu, L.S, Pozharski, E, Drohat, A.C. | 登録日 | 2019-08-15 | 公開日 | 2019-11-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. J.Am.Chem.Soc., 141, 2019
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6U15
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6U16
| Human thymine DNA glycosylase N140A mutant bound to DNA with 5-carboxyl-dC substrate | 分子名称: | 1,2-ETHANEDIOL, DNA (28-MER), G/T mismatch-specific thymine DNA glycosylase | 著者 | Pidugu, L.S, Pozharski, E, Drohat, A.C. | 登録日 | 2019-08-15 | 公開日 | 2019-11-20 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase. J.Am.Chem.Soc., 141, 2019
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