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8C4S
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BU of 8c4s by Molmil
Apo Hantaan virus polymerase core
Descriptor: RNA-directed RNA polymerase L
Authors:Durieux trouilleton, Q, Arragain, B, Malet, H.
Deposit date:2023-01-04
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
8C4T
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BU of 8c4t by Molmil
Hantaan virus polymerase bound to its 5' viral RNA
Descriptor: MAGNESIUM ION, RNA (5'-R(P*UP*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*A)-3'), RNA-directed RNA polymerase L
Authors:Durieux trouilleton, Q, Arragain, B, Malet, H.
Deposit date:2023-01-04
Release date:2023-06-07
Method:ELECTRON MICROSCOPY (3.23 Å)
Cite:Structures of active Hantaan virus polymerase uncover the mechanisms of Hantaviridae genome replication.
Nat Commun, 14, 2023
6Z8K
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BU of 6z8k by Molmil
La Crosse virus polymerase at elongation mimicking stage
Descriptor: La Crosse virus 3' vRNA (1-16), La Crosse virus 5' vRNA (9-16), La Crosse virus 5' vRNA 1-10, ...
Authors:Arragain, B, Effantin, G, Schoehn, G, Cusack, S, Malet, H.
Deposit date:2020-06-02
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.02 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
6Z6G
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BU of 6z6g by Molmil
Cryo-EM structure of La Crosse virus polymerase at pre-initiation stage
Descriptor: 3'vRNA 1-16, 5'vRNA 1-10, 5'vRNA 9-16, ...
Authors:Arragain, B, Effantin, G, Gerlach, P, Reguera, J, Schoehn, G, Cusack, S, Malet, H.
Deposit date:2020-05-28
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Pre-initiation and elongation structures of full-length La Crosse virus polymerase reveal functionally important conformational changes.
Nat Commun, 11, 2020
4TU0
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BU of 4tu0 by Molmil
CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
Descriptor: 2'-5' OLIGOADENYLATE TRIMER, DI(HYDROXYETHYL)ETHER, Non-structural polyprotein 3
Authors:Morin, B, Ferron, f.p, Malet, h, Coutard, b, Canard, b.
Deposit date:2014-06-23
Release date:2014-07-09
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:CRYSTAL STRUCTURE OF CHIKUNGUNYA VIRUS NSP3 MACRO DOMAIN IN COMPLEX WITH A 2'-5' OLIGOADENYLATE TRIMER
TO BE PUBLISHED
3STI
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BU of 3sti by Molmil
Crystal structure of the protease domain of DegQ from Escherichia coli
Descriptor: Protease degQ
Authors:Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
3STJ
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BU of 3stj by Molmil
Crystal structure of the protease + PDZ1 domain of DegQ from Escherichia coli
Descriptor: Protease degQ, peptide (UNK)
Authors:Sawa, J, Malet, H, Krojer, T, Canellas, F, Ehrmann, M, Clausen, T.
Deposit date:2011-07-11
Release date:2011-07-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular adaptation of the DegQ protease to exert protein quality control in the bacterial cell envelope.
J.Biol.Chem., 286, 2011
8CI5
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BU of 8ci5 by Molmil
Structure of the SNV L protein bound to 5' RNA
Descriptor: RNA (5'-R(P*AP*GP*UP*AP*GP*UP*AP*GP*AP*CP*U)-3'), RNA-directed RNA polymerase L
Authors:Meier, K, Thorkelsson, S.R, Durieux Trouilleton, Q, Vogel, D, Yu, D, Kosinski, J, Cusack, S, Malet, H, Grunewald, K, Quemin, E.R.J, Rosenthal, M.
Deposit date:2023-02-08
Release date:2023-07-19
Last modified:2023-08-23
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and functional characterization of the Sin Nombre virus L protein.
Plos Pathog., 19, 2023
5FL2
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BU of 5fl2 by Molmil
Revisited cryo-EM structure of Inducible lysine decarboxylase complexed with LARA domain of RavA ATPase
Descriptor: ATPASE RAVA, LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I.
Deposit date:2015-10-21
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
6I2N
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BU of 6i2n by Molmil
Helical RNA-bound Hantaan virus nucleocapsid
Descriptor: Nucleoprotein, RNA (5'-R(P*UP*UP*U)-3')
Authors:Arragain, B, Reguera, J, Desfosses, A, Gutsche, I, Schoehn, G, Malet, H.
Deposit date:2018-11-01
Release date:2019-01-23
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms.
Elife, 8, 2019
7ORO
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BU of 7oro by Molmil
La Crosse virus polymerase at replication early-elongation stage
Descriptor: La Crosse virus polymerase, MAGNESIUM ION, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
7ORI
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BU of 7ori by Molmil
La Crosse virus polymerase at replication late-elongation stage
Descriptor: La Crosse virus polymerase, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
7ORJ
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BU of 7orj by Molmil
La Crosse virus polymerase at transcription capped RNA cleavage stage
Descriptor: 5' capped RNA, ADENOSINE-5'-TRIPHOSPHATE, RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*CP*AP*AP*G)-3'), ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
7ORM
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BU of 7orm by Molmil
La Crosse virus polymerase at transcription early-elongation stage
Descriptor: MAGNESIUM ION, RNA (5'-R(P*AP*AP*AP*GP*UP*AP*CP*AP*CP*UP*AP*CP*U)-3'), RNA (5'-R(P*AP*CP*GP*AP*GP*UP*GP*UP*CP*GP*UP*AP*CP*C)-3'), ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
7ORN
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BU of 7orn by Molmil
La Crosse virus polymerase at replication initiation stage
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, La Crosse virus polymerase, MAGNESIUM ION, ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
7ORK
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BU of 7ork by Molmil
La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (5'-D(*(GTG))-R(P*A)-3'), ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
7ORL
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BU of 7orl by Molmil
La Crosse virus polymerase at transcription initiation stage
Descriptor: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Arragain, B, Durieux Trouilleton, Q, Baudin, F, Cusack, S, Schoehn, G, Malet, H.
Deposit date:2021-06-06
Release date:2022-02-16
Last modified:2022-03-02
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural snapshots of La Crosse virus polymerase reveal the mechanisms underlying Peribunyaviridae replication and transcription.
Nat Commun, 13, 2022
2FAV
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BU of 2fav by Molmil
Crystal structure of SARS macro domain in complex with ADP-ribose at 1.8 A resolution
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, Replicase polyprotein 1ab (pp1ab) (ORF1AB)
Authors:Egloff, M.P, Malet, H, Marseilles Structural Genomics Program @ AFMB (MSGP)
Deposit date:2005-12-08
Release date:2006-10-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional basis for ADP-ribose and poly(ADP-ribose) binding by viral macro domains.
J.Virol., 80, 2006
4BGP
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BU of 4bgp by Molmil
Crystal structure of La Crosse virus nucleoprotein
Descriptor: GLYCEROL, NUCLEOPROTEIN, SULFATE ION
Authors:Reguera, J, Malet, H, Weber, F, Cusack, S.
Deposit date:2013-03-28
Release date:2013-04-24
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis for Encapsidation of Genomic RNA by La Crosse Orthobunyavirus Nucleoprotein
Proc.Natl.Acad.Sci.USA, 110, 2013
4BHH
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BU of 4bhh by Molmil
Crystal structure of tetramer of La Crosse virus nucleoprotein in complex with ssRNA
Descriptor: NUCLEOPROTEIN, POLY-URIDINE 45-MER
Authors:Reguera, J, Malet, H, Weber, F, Cusack, S.
Deposit date:2013-04-03
Release date:2013-04-24
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural Basis for Encapsidation of Genomic RNA by La Crosse Orthobunyavirus Nucleoprotein.
Proc.Natl.Acad.Sci.USA, 110, 2013
5FKX
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BU of 5fkx by Molmil
Structure of E.coli inducible lysine decarboxylase at active pH
Descriptor: LYSINE DECARBOXYLASE, INDUCIBLE
Authors:Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
5FKZ
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BU of 5fkz by Molmil
Structure of E.coli Constitutive lysine decarboxylase
Descriptor: LYSINE DECARBOXYLASE, CONSTITUTIVE
Authors:Kandiah, E, Carriel, D, Perard, J, Malet, H, Bacia, M, Liu, K, Chan, S.W.S, Houry, W.A, Ollagnier de Choudens, S, Elsen, S, Gutsche, I.
Deposit date:2015-10-20
Release date:2016-09-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structural Insights Into the Escherichia Coli Lysine Decarboxylases and Molecular Determinants of Interaction with the Aaa+ ATPase Rava.
Sci.Rep., 6, 2016
2J7U
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BU of 2j7u by Molmil
Dengue virus NS5 RNA dependent RNA polymerase domain
Descriptor: CHLORIDE ION, MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE, ...
Authors:Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7W
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BU of 2j7w by Molmil
Dengue virus NS5 RNA dependent RNA polymerase domain complexed with 3' dGTP
Descriptor: DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-TRIPHOSPHATE, POLYPROTEIN, ...
Authors:Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
5LDF
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BU of 5ldf by Molmil
Maltose binding protein genetically fused to dodecameric glutamine synthetase
Descriptor: Glutamine synthetase, Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Coscia, F, Petosa, C, Schoehn, G.
Deposit date:2016-06-25
Release date:2016-08-10
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:Fusion to a homo-oligomeric scaffold allows cryo-EM analysis of a small protein.
Sci Rep, 6, 2016

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