5MM2
 
 | | nora virus structure | | Descriptor: | Capsid protein VP4A, capsid protein VP4B, capsid protein VP4C | | Authors: | Laurinmaki, P, Shakeel, S, Ekstrom, J.-O, Butcher, S.J. | | Deposit date: | 2016-12-08 | | Release date: | 2017-12-20 | | Last modified: | 2022-12-14 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structure of Nora virus at 2.7 angstrom resolution and implications for receptor binding, capsid stability and taxonomy.
Sci Rep, 10, 2020
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1L8B
 | | Cocrystal Structure of the Messenger RNA 5' Cap-binding Protein (eIF4E) bound to 7-methylGpppG | | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E | | Authors: | Niedzwiecka, A, Marcotrigiano, J, Stepinski, J, Jankowska-Anyszka, M, Wyslouch-Cieszynska, A, Dadlez, M, Gingras, A.-C, Mak, P, Darzynkiewicz, E, Sonenberg, N. | | Deposit date: | 2002-03-19 | | Release date: | 2002-06-12 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins.
J.Mol.Biol., 319, 2002
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7NYI
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5LWC
 | | NMR solution structure of bacteriocin BacSp222 from Staphylococcus pseudintermedius 222 | | Descriptor: | Bacteriocin BacSp222 | | Authors: | Nowakowski, M.E, Ejchart, A.O, Jaremko, L, Wladyka, B, Mak, P. | | Deposit date: | 2016-09-15 | | Release date: | 2017-10-25 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Spatial attributes of the four-helix bundle group of bacteriocins - The high-resolution structure of BacSp222 in solution.
Int.J.Biol.Macromol., 107, 2018
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1U4D
 | | Structure of the ACK1 Kinase Domain bound to Debromohymenialdisine | | Descriptor: | Activated CDC42 kinase 1, CHLORIDE ION, DEBROMOHYMENIALDISINE | | Authors: | Lougheed, J.C, Chen, R.H, Mak, P, Stout, T.J. | | Deposit date: | 2004-07-23 | | Release date: | 2004-08-31 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1.
J.Biol.Chem., 279, 2004
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1U46
 | | Crystal Structure of the Unphosphorylated Kinase Domain of the Tyrosine Kinase ACK1 | | Descriptor: | Activated CDC42 kinase 1, CHLORIDE ION | | Authors: | Lougheed, J.C, Chen, R.H, Mak, P, Stout, T.J. | | Deposit date: | 2004-07-23 | | Release date: | 2004-08-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1.
J.Biol.Chem., 279, 2004
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1U54
 | | Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the CDC42-associated Tyrosine Kinase ACK1 bound to AMP-PCP | | Descriptor: | Activated CDC42 kinase 1, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | | Authors: | Lougheed, J.C, Chen, R.H, Mak, P, Stout, T.J. | | Deposit date: | 2004-07-26 | | Release date: | 2004-08-31 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1.
J.Biol.Chem., 279, 2004
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3J2J
 | | Empty coxsackievirus A9 capsid | | Descriptor: | Protein VP1, Protein VP2, Protein VP3 | | Authors: | Shakeel, S, Seitsonen, J.J.T, Kajander, T, Laurinmaki, P, Hyypia, T, Susi, P, Butcher, S.J. | | Deposit date: | 2012-10-04 | | Release date: | 2013-07-17 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (9.54 Å) | | Cite: | Structural and functional analysis of coxsackievirus A9 integrin {alpha}v{beta}6 binding and uncoating.
J.Virol., 87, 2013
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4BIQ
 | | Homology model of coxsackievirus A7 (CAV7) empty capsid proteins. | | Descriptor: | VP1, VP2, VP3 | | Authors: | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | | Deposit date: | 2013-04-12 | | Release date: | 2013-10-02 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (6.09 Å) | | Cite: | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change.
J.Struct.Biol., 185, 2014
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4BIP
 | | Homology model of coxsackievirus A7 (CAV7) full capsid proteins. | | Descriptor: | VP1, VP2, VP3 | | Authors: | Seitsonen, J.J.T, Shakeel, S, Susi, P, Pandurangan, A.P, Sinkovits, R.S, Hyvonen, H, Laurinmaki, P, Yla-Pelto, J, Topf, M, Hyypia, T, Butcher, S.J. | | Deposit date: | 2013-04-12 | | Release date: | 2013-10-02 | | Last modified: | 2018-10-03 | | Method: | ELECTRON MICROSCOPY (8.23 Å) | | Cite: | Combined Approaches to Flexible Fitting and Assessment in Virus Capsids Undergoing Conformational Change.
J.Struct.Biol., 185, 2014
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4K1S
 | | Gly-Ser-SplB protease from Staphylococcus aureus at 1.96 A resolution | | Descriptor: | Serine protease SplB | | Authors: | Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G. | | Deposit date: | 2013-04-05 | | Release date: | 2014-04-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.96 Å) | | Cite: | Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation.
J.Biol.Chem., 289, 2014
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4K1T
 | | Gly-Ser-SplB protease from Staphylococcus aureus at 1.60 A resolution | | Descriptor: | CHLORIDE ION, SULFATE ION, Serine protease SplB, ... | | Authors: | Zdzalik, M, Pustelny, K, Stec-Niemczyk, J, Cichon, P, Czarna, A, Popowicz, G, Drag, M, Wladyka, B, Potempa, J, Dubin, A, Dubin, G. | | Deposit date: | 2013-04-05 | | Release date: | 2014-04-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Staphylococcal SplB Serine Protease Utilizes a Novel Molecular Mechanism of Activation.
J.Biol.Chem., 289, 2014
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4Q56
 | | Structure of Helix aspersa agglutinin with natural glycosylation and N-acetyl-alpha-D-galactosamine (GalNAc) | | Descriptor: | 2-acetamido-2-deoxy-alpha-D-galactopyranose, ACETATE ION, Helix aspersa agglutinin (HAA), ... | | Authors: | Pietrzyk, A.J, Bujacz, A, Bujacz, G. | | Deposit date: | 2014-04-16 | | Release date: | 2015-10-14 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.38 Å) | | Cite: | Structural studies of Helix aspersa agglutinin complexed with GalNAc: A lectin that serves as a diagnostic tool.
Int.J.Biol.Macromol., 81, 2015
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7SKM
 | | Complex between S. aureus aureolysin and wt IMPI. | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Mendes, S.R, Eckhard, U, Rodriguez-Banqueri, A, Guevara, T, Gomis-Ruth, F.X. | | Deposit date: | 2021-10-21 | | Release date: | 2022-01-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin
Comput Struct Biotechnol J, 20, 2022
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7SKL
 | | Complex between S. aureus aureolysin and IMPI mutant I57I | | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, IMPI alpha, ... | | Authors: | Mendes, S.R, Eckhard, U, Rodriguez-Banqueri, A, Guevara, T, Gomis-Ruth, F.X. | | Deposit date: | 2021-10-21 | | Release date: | 2022-01-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin
Comput Struct Biotechnol J, 20, 2022
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6T8P
 | | HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide | | Descriptor: | 1,2-ETHANEDIOL, 3,5-bis(fluoranyl)-~{N}-[5-[(2~{R})-2-(3-fluorophenyl)-3-methyl-butyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide, IODIDE ION, ... | | Authors: | Blaesse, M, Venalainen, J. | | Deposit date: | 2019-10-24 | | Release date: | 2020-03-04 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
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6T8Q
 | | HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide | | Descriptor: | (2~{R})-1-[6-methyl-5-(oxan-4-yl)-7-oxidanylidene-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]-~{N}-(phenylmethyl)pyrrolidine-2-carboxamide, ACETATE ION, CADMIUM ION, ... | | Authors: | Blaesse, M, Venalainen, J. | | Deposit date: | 2019-10-24 | | Release date: | 2020-03-04 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
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