Crystal Structure of the Unphosphorylated Kinase Domain of the Tyrosine Kinase ACK1

Summary for 1U46

Related1U4D 1U54
DescriptorActivated CDC42 kinase 1, CHLORIDE ION (3 entities in total)
Functional Keywordstyrosine kinase, transferase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane Q07912
Total number of polymer chains2
Total molecular weight66151.55
Lougheed, J.C.,Chen, R.H.,Mak, P.,Stout, T.J. (deposition date: 2004-07-23, release date: 2004-08-31, Last modification date: 2011-07-13)
Primary citation
Lougheed, J.C.,Chen, R.H.,Mak, P.,Stout, T.J.
Crystal Structures of the Phosphorylated and Unphosphorylated Kinase Domains of the Cdc42-associated Tyrosine Kinase ACK1.
J.Biol.Chem., 279:44039-44045, 2004
PubMed: 15308621 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M406703200
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24940.2%3.6%4.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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