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1U46

Crystal Structure of the Unphosphorylated Kinase Domain of the Tyrosine Kinase ACK1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Activated CDC42 kinase 1polymer29133058.02UniProt (Q07912)
Pfam (PF07714)
Homo sapiens (human)ACK-1
2C
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
3D, E
(A, B)
waterwater18.0230Chemie (HOH)
Sequence modifications
A, B: 109 - 395 (UniProt: Q07912)
PDBExternal DatabaseDetails
Gly 107-cloning artifact
Ser 108-cloning artifact
Glu 396-cloning artifact
Phe 397-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight66116.1
Non-Polymers*Number of molecules1
Total formula weight35.5
All*Total formula weight66151.5
*Water molecules are not included.

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PDB entries from 2025-12-17

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