7WSO
| Structure of a membrane protein G | Descriptor: | B-cell antigen receptor complex-associated protein alpha chain, B-cell antigen receptor complex-associated protein beta chain, Immunoglobulin heavy constant gamma 1 | Authors: | Ma, X, Zhu, Y, Chen, Y, Huang, Z. | Deposit date: | 2022-01-30 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (3.03 Å) | Cite: | Cryo-EM structures of two human B cell receptor isotypes. Science, 377, 2022
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7XT6
| Structure of a membrane protein M3 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell antigen receptor complex-associated protein alpha chain, ... | Authors: | Ma, X, Zhu, Y, Chen, Y, Huang, Z. | Deposit date: | 2022-05-16 | Release date: | 2022-08-31 | Method: | ELECTRON MICROSCOPY (3.63 Å) | Cite: | Cryo-EM structures of two human B cell receptor isotypes. Science, 377, 2022
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5H0N
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5HFM
| Gp41-targeting HIV-1 fusion inhibitors with hook-like Ile-Asp-Leu tail | Descriptor: | Envelope glycoprotein gp160,gp41 CHR region, TRIS(HYDROXYETHYL)AMINOMETHANE | Authors: | Zhu, Y, Ye, S, Zhang, R. | Deposit date: | 2016-01-07 | Release date: | 2017-01-11 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.298 Å) | Cite: | Rational improvement of gp41-targeting HIV-1 fusion inhibitors: an innovatively designed Ile-Asp-Leu tail with alternative conformations Sci Rep, 6, 2016
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5HFL
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8ILX
| mCherry-LaM3 complex | Descriptor: | LAM3, MCherry fluorescent protein | Authors: | Liang, H, Liu, R, Ding, Y. | Deposit date: | 2023-03-05 | Release date: | 2023-06-21 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies. Int J Mol Sci, 24, 2023
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8IM1
| mCherry-LaM1 complex | Descriptor: | LaM1, MCherry fluorescent protein, SULFATE ION | Authors: | Liang, H, Liu, R, Ding, Y. | Deposit date: | 2023-03-05 | Release date: | 2023-06-21 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies. Int J Mol Sci, 24, 2023
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8IM0
| mCherry-LaM8 complex | Descriptor: | LaM8, MCherry fluorescent protein | Authors: | Liang, H, Liu, R, Ding, Y. | Deposit date: | 2023-03-05 | Release date: | 2023-06-21 | Method: | X-RAY DIFFRACTION (1.31 Å) | Cite: | Structural Insights into the Binding of Red Fluorescent Protein mCherry-Specific Nanobodies. Int J Mol Sci, 24, 2023
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8IYS
| TUG891-bound FFAR4 in complex with Gq | Descriptor: | 3-{4-[(4-fluoro-4'-methyl[1,1'-biphenyl]-2-yl)methoxy]phenyl}propanoic acid, Free fatty acid receptor 4, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | He, Y, Yin, H. | Deposit date: | 2023-04-06 | Release date: | 2023-06-21 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (2.95 Å) | Cite: | Structural basis of omega-3 fatty acid receptor FFAR4 activation and G protein coupling selectivity. Cell Res., 33, 2023
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1DFJ
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8KAE
| 16d-bound human SPNS2 | Descriptor: | 3-[3-(4-decylphenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine, NbFab chain L, NbFab-H chain, ... | Authors: | He, Y, Duan, Y. | Deposit date: | 2023-08-03 | Release date: | 2024-01-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.18 Å) | Cite: | Structural basis of Sphingosine-1-phosphate transport via human SPNS2. Cell Res., 34, 2024
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7BUJ
| mcGAS bound with pppGpG | Descriptor: | Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Wang, B, Su, X.D. | Deposit date: | 2020-04-07 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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7BUM
| mcGAS bound with pGpA | Descriptor: | ADENOSINE-5'-MONOPHOSPHATE, Cyclic GMP-AMP synthase, GUANOSINE-5'-MONOPHOSPHATE, ... | Authors: | Wang, B, Su, X.D. | Deposit date: | 2020-04-07 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.047 Å) | Cite: | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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7BUQ
| mcGAS bound with 23-cGAMP | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION, cGAMP | Authors: | Wang, B, Su, X.D. | Deposit date: | 2020-04-07 | Release date: | 2020-09-02 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.091 Å) | Cite: | Mn2+Directly Activates cGAS and Structural Analysis Suggests Mn2+Induces a Noncanonical Catalytic Synthesis of 2'3'-cGAMP. Cell Rep, 32, 2020
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5YS8
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3R60
| Structure of the MntR Fe2+ Complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE (II) ION, S-1,2-PROPANEDIOL, ... | Authors: | Glasfeld, A, Brophy, M.B, Kliegman, J.I, Griner, S.L, Nix, J.C. | Deposit date: | 2011-03-20 | Release date: | 2012-04-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Roles of the A and C Sites in the Manganese-Specific Activation of MntR. Biochemistry, 52, 2013
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4HX7
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4HV6
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4HX8
| Structure of metal-free MNTR mutant E11K | Descriptor: | Transcriptional regulator MntR | Authors: | Glasfeld, A, Mcguire, A. | Deposit date: | 2012-11-09 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.001 Å) | Cite: | Roles of the A and C Sites in the Manganese-Specific Activation of MntR. Biochemistry, 52, 2013
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4I7H
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4HV5
| Structure of the MNTR FE2+ complex with E site metal binding | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FE (II) ION, Transcriptional regulator MntR | Authors: | Glasfeld, A, Brophy, M.B, Kliegman, J.I, Griner, S.L. | Deposit date: | 2012-11-05 | Release date: | 2012-11-14 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Roles of the A and C sites in the manganese-specific activation of MntR. Biochemistry, 52, 2013
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4HX4
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3R61
| Structure of the MntR Co2+ Complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, Transcriptional regulator mntR | Authors: | Glasfeld, A, Brophy, M.B, Kliegman, J.I, Griner, S.L, Nix, J.C. | Deposit date: | 2011-03-20 | Release date: | 2012-04-11 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9002 Å) | Cite: | Roles of the A and C Sites in the Manganese-Specific Activation of MntR. Biochemistry, 52, 2013
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6WYS
| Lon protease proteolytic domain | Descriptor: | Lon protease homolog, mitochondrial, SULFATE ION | Authors: | Lee, C.C, Spraggon, G. | Deposit date: | 2020-05-13 | Release date: | 2021-04-14 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.229 Å) | Cite: | Structure-Based Design of Selective LONP1 Inhibitors for Probing In Vitro Biology. J.Med.Chem., 64, 2021
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6X1M
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