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5YOD
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BU of 5yod by Molmil
Crystal structure of zika virus NS3 protease in complex with a small molecule inhibitor
Descriptor: BENZOIC ACID, NS2B cofactor, NS3 protease
Authors:Phoo, W.W, Zhang, Z.Z.
Deposit date:2017-10-27
Release date:2018-03-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018
5YVJ
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BU of 5yvj by Molmil
Crystal structure of full length NS2B47-NS3 (gD4NS2BNS3) from Dengue virus 4 in open conformation
Descriptor: GLYCEROL, Genome polyprotein
Authors:Phoo, W.W, El Sahili, A.
Deposit date:2017-11-26
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.508 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVV
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BU of 5yvv by Molmil
Crystal structure of full length NS3 protein (gD4NS2BNS3) from DENV4 in closed conformation
Descriptor: Genome polyprotein
Authors:PHOO, W.W, Sahili, A.E.
Deposit date:2017-11-27
Release date:2018-12-05
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.097 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVW
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BU of 5yvw by Molmil
Crystal structure of full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Genome polyprotein
Authors:PHOO, W.W, El Sahili, A.
Deposit date:2017-11-27
Release date:2018-12-05
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5ZOB
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BU of 5zob by Molmil
Crystal structure of Zika NS3 protease with 4-guanidinomethyl-phenylacetyl-Arg-Arg-Arg-4-amidinobenzylamide
Descriptor: 4-guanidinomethyl-phenylacetyl-Arg-Arg-Arg-4-amidinobenzylamide, NS3 protease, Serine protease subunit NS2B
Authors:Phoo, W.W, Wirawan, M.
Deposit date:2018-04-12
Release date:2018-10-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160, 2018
5YW1
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BU of 5yw1 by Molmil
Crystal structure of full length NS3 protein (eD4NS2BNS3) in complex with Bovine Pancreatic Trypsin Inhibitor
Descriptor: FLAVIVIRUS_NS2B, PTI protein, Peptidase S7
Authors:Phoo, W.W, El Sahili, A.
Deposit date:2017-11-28
Release date:2019-01-02
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVU
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BU of 5yvu by Molmil
Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
Descriptor: GLYCEROL, Genome polyprotein, Pancreatic trypsin inhibitor
Authors:Phoo, W.W, El Sahili, A.
Deposit date:2017-11-27
Release date:2018-11-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.491 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5YVY
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BU of 5yvy by Molmil
Crystal structure of unlinked full length NS3 protein (eD4NS2BNS3) from DENV4 in closed conformation
Descriptor: Genome polyprotein
Authors:PHOO, W.W, El Sahili, A.
Deposit date:2017-11-27
Release date:2018-11-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of unlinked full length NS3 from Dengue virus provide insights into dynamics of protease domain
To Be Published
5ZMQ
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BU of 5zmq by Molmil
Crystal structure of Zika NS3 protease with phenylacetyl-Lys-Lys-Arg-COOH inhibitor
Descriptor: Serine protease NS3, Serine protease subunit NS2B, peptide PAC-DLY-DLY-DAR
Authors:Phoo, W.W, Wirawan, M.
Deposit date:2018-04-05
Release date:2018-10-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.987 Å)
Cite:Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160, 2018
5ZMS
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BU of 5zms by Molmil
Crystal structure of Zika NS3 protease in complex with 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H
Descriptor: 4-guanidinomethyl-phenylacetyl-Lys-Lys-Arg-H, NS3 protease, Serine protease subunit NS2B
Authors:Phoo, W.W, Wirawan, M.
Deposit date:2018-04-05
Release date:2018-10-17
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors.
Antiviral Res., 160, 2018
7FAV
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BU of 7fav by Molmil
Crystal Structure of Rubella Protease
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Quek, J.P.
Deposit date:2021-07-07
Release date:2022-07-13
Last modified:2022-09-14
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Crystal structure of the Rubella virus protease reveals a unique papain-like protease fold.
J.Biol.Chem., 298, 2022
7DOC
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BU of 7doc by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 5
Descriptor: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Core protein, Genome polyprotein, ...
Authors:Quek, J.P.
Deposit date:2020-12-14
Release date:2021-04-14
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.904 Å)
Cite:2-Cyanoisonicotinamide Conjugation: A Facile Approach to Generate Potent Peptide Inhibitors of the Zika Virus Protease.
Acs Med.Chem.Lett., 12, 2021
6JIM
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BU of 6jim by Molmil
Viral helicase protein
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM ION, CHLORIDE ION, ...
Authors:Law, Y.S.
Deposit date:2019-02-22
Release date:2019-04-10
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insights into RNA recognition by the Chikungunya virus nsP2 helicase.
Proc.Natl.Acad.Sci.USA, 116, 2019
6JPW
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BU of 6jpw by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 1C
Descriptor: NS3 protease, SER-C0F-GLY-LYS-ARG-LYS, Serine protease subunit NS2B
Authors:Quek, J.P.
Deposit date:2019-03-28
Release date:2019-06-26
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.951 Å)
Cite:Biocompatible Macrocyclization between Cysteine and 2-Cyanopyridine Generates Stable Peptide Inhibitors.
Org.Lett., 21, 2019
6L4Z
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BU of 6l4z by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 6
Descriptor: 4-(hydroxymethyl)benzoic acid, Genome polyprotein
Authors:Quek, J.P.
Deposit date:2019-10-21
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
Antiviral Res., 175, 2020
6L50
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BU of 6l50 by Molmil
Crystal structure of Zika NS2B-NS3 protease with compound 16
Descriptor: 2-sulfanylidene-1,3-thiazolidin-4-one, NS3 protease, Serine protease subunit NS2B
Authors:Quek, J.P.
Deposit date:2019-10-21
Release date:2020-07-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Identification and structural characterization of small molecule fragments targeting Zika virus NS2B-NS3 protease.
Antiviral Res., 175, 2020

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PDB entries from 2024-04-24

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