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6ENT
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BU of 6ent by Molmil
Structure of the rat RKIP variant delta143-146
分子名称: CHLORIDE ION, Phosphatidylethanolamine-binding protein 1, ZINC ION
著者Koelmel, W, Hirschbeck, M, Schindelin, H, Lorenz, K, Kisker, C.
登録日2017-10-06
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6ENS
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BU of 6ens by Molmil
Structure of mouse wild-type RKIP
分子名称: ACETATE ION, GLYCEROL, Phosphatidylethanolamine-binding protein 1
著者Hirschbeck, M, Koelmel, W, Schindelin, H, Lorenz, K, Kisker, C.
登録日2017-10-06
公開日2017-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5NIQ
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BU of 5niq by Molmil
exendin-4 variant with dual GLP-1 / glucagon receptor activity
分子名称: Exendin-4, N-hexadecanoyl-L-glutamic acid
著者Evers, A, Kurz, M.
登録日2017-03-24
公開日2018-02-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Design of Novel Exendin-Based Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists.
J.Med.Chem., 60, 2017
6GB1
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BU of 6gb1 by Molmil
Crystal structure of the GLP1 receptor ECD with Peptide 11
分子名称: Glucagon-like peptide 1 receptor, HEXANE-1,6-DIOL, Peptide 11, ...
著者Schreuder, H.A, Liesum, A.
登録日2018-04-13
公開日2018-06-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J. Med. Chem., 61, 2018
6GDZ
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BU of 6gdz by Molmil
exendin-4 based dual GLP-1/glucagon receptor agonist
分子名称: (2~{S})-2-[[(4~{S})-4-(hexadecanoylamino)-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid, Exendin-4
著者Evers, A, Kurz, M.
登録日2018-04-25
公開日2018-06-20
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J. Med. Chem., 61, 2018
6GE2
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BU of 6ge2 by Molmil
exendin-4 based dual GLP-1/glucagon receptor agonist
分子名称: (2~{S})-2-[[(4~{S})-4-(hexadecanoylamino)-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]pentanedioic acid, Exendin-4
著者Evers, A, Kurz, M.
登録日2018-04-25
公開日2018-06-20
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Dual Glucagon-like Peptide 1 (GLP-1)/Glucagon Receptor Agonists Specifically Optimized for Multidose Formulations.
J. Med. Chem., 61, 2018
8F2A
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BU of 8f2a by Molmil
Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385 (Cluster 5 conformation)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Cao, J, Sexton, P.M, Wootten, D.L, Radostin, D.
登録日2022-11-07
公開日2023-08-02
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
8F0K
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BU of 8f0k by Molmil
Human Amylin3 Receptor in complex with Gs and Pramlintide analogue peptide San385
分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Cao, J, Sexton, P.M, Wootten, D.L.
登録日2022-11-03
公開日2023-08-02
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (1.9 Å)
主引用文献Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
8F0J
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BU of 8f0j by Molmil
Calcitonin Receptor in complex with Gs and Pramlintide analogue peptide San45
分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Cao, J, Sexton, P.M, Wootten, D.L, Belousoff, M.J.
登録日2022-11-03
公開日2023-08-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024
8F2B
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BU of 8f2b by Molmil
Amylin 3 Receptor in complex with Gs and Pramlintide analogue peptide San45
分子名称: (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Cao, J, Sexton, P.M, Wootten, D.L, Belousoff, M.J.
登録日2022-11-07
公開日2023-08-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (2 Å)
主引用文献Structural insight into selectivity of amylin and calcitonin receptor agonists.
Nat.Chem.Biol., 20, 2024

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件を2024-05-22に公開中

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