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6FGU
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BU of 6fgu by Molmil
Crystal Structure of BAZ2B bromodomain in complex with 1-methylpyridinone compound 4
Descriptor: 1-methyl-6-oxidanylidene-~{N}-(2-pyrrolidin-1-ylethyl)pyridine-3-carboxamide, Bromodomain adjacent to zinc finger domain protein 2B
Authors:Dalle Vedove, A, Spiliotopoulos, D, Lolli, G, Caflisch, A.
Deposit date:2018-01-11
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains.
ChemMedChem, 13, 2018
6FGW
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BU of 6fgw by Molmil
Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 4
Descriptor: 1-methyl-6-oxidanylidene-~{N}-(2-pyrrolidin-1-ylethyl)pyridine-3-carboxamide, Bromodomain adjacent to zinc finger domain protein 2A
Authors:Dalle Vedove, A, Spiliotopoulos, D, Lolli, G, Caflisch, A.
Deposit date:2018-01-11
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.725 Å)
Cite:Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains.
ChemMedChem, 13, 2018
6FGG
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BU of 6fgg by Molmil
Crystal Structure of BAZ2A bromodomain in complex with 1-methylpyridinone compound 5
Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, ~{N}-[3-[2-(dimethylamino)ethyl]-2-oxidanylidene-1,3-benzoxazol-5-yl]-1-methyl-6-oxidanylidene-pyridine-3-carboxamide
Authors:Dalle Vedove, A, Spiliotopoulos, D, Lolli, G, Caflisch, A.
Deposit date:2018-01-10
Release date:2018-05-30
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains.
ChemMedChem, 13, 2018
2IVX
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BU of 2ivx by Molmil
Crystal structure of human cyclin T2 at 1.8 A resolution
Descriptor: 1,2-ETHANEDIOL, CYCLIN-T2
Authors:Debreczeni, J.E, Bullock, A.N, Fedorov, O, Savitsky, P, Berridge, G, Das, S, Pike, A.C.W, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Gorrec, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S.
Deposit date:2006-06-21
Release date:2006-07-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J., 27, 2008
3Q04
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BU of 3q04 by Molmil
Crystal structure of the apo-form of human CK2 alpha at pH 8.5
Descriptor: 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION
Authors:Battistutta, R, Ranchio, A, Papinutto, E.
Deposit date:2010-12-15
Release date:2011-12-21
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
to be published
3PZH
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BU of 3pzh by Molmil
Crystal structure of maize CK2 alpha in complex with emodin at 1.92 A resolution
Descriptor: 1,2-ETHANEDIOL, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, ACETATE ION, ...
Authors:Battistutta, R, Mazzorana, M.
Deposit date:2010-12-14
Release date:2011-12-21
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.919 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
to be published
3QA0
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BU of 3qa0 by Molmil
Crystal structure of the apo-form of human CK2 alpha at pH 6.5
Descriptor: 1,2-ETHANEDIOL, Casein kinase II subunit alpha, SULFATE ION
Authors:Battistutta, R, Ranchio, A, Papinutto, E.
Deposit date:2011-01-10
Release date:2012-01-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
To be Published
3Q9Z
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BU of 3q9z by Molmil
Crystal structure of human CK2 alpha in complex with Quinalizarin at pH 6.5
Descriptor: 1,2,5,8-tetrahydroxyanthracene-9,10-dione, 1,2-ETHANEDIOL, Casein kinase II subunit alpha, ...
Authors:Battistutta, R, Ranchio, A, Papinutto, E.
Deposit date:2011-01-10
Release date:2012-01-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
To be Published
3Q9X
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BU of 3q9x by Molmil
Crystal structure of human CK2 alpha in complex with emodin at pH 6.5
Descriptor: 1,2-ETHANEDIOL, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, ...
Authors:Battistutta, R, Ranchio, A, Papinutto, E.
Deposit date:2011-01-10
Release date:2012-01-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
To be Published
3Q9Y
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BU of 3q9y by Molmil
Crystal structure of human CK2 alpha in complex with Quinalizarin at pH 8.5
Descriptor: 1,2,5,8-tetrahydroxyanthracene-9,10-dione, Casein kinase II subunit alpha, SULFATE ION
Authors:Battistutta, R, Ranchio, A, Papinutto, E.
Deposit date:2011-01-10
Release date:2012-01-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
To be Published
3Q9W
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BU of 3q9w by Molmil
Crystal structure of human CK2 alpha in complex with emodin at pH 8.5
Descriptor: 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE, Casein kinase II subunit alpha, SULFATE ION
Authors:Battistutta, R, Ranchio, A, Papinutto, E.
Deposit date:2011-01-10
Release date:2012-01-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional analysis of the flexible regions of the catalytic alpha-subunit of protein kinase CK2
To be Published
5D7X
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BU of 5d7x by Molmil
Crystal structure of the human BRPF1 bromodomain in complex with XZ08
Descriptor: 4-(1-acetyl-1H-indol-3-yl)-5-methyl-1,2-dihydro-3H-pyrazol-3-one, NITRATE ION, Peregrin
Authors:Zhu, J, Caflisch, A.
Deposit date:2015-08-14
Release date:2016-05-25
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The "Gatekeeper" Residue Influences the Mode of Binding of Acetyl Indoles to Bromodomains.
J.Med.Chem., 59, 2016
6ISJ
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BU of 6isj by Molmil
Crystal structure of CX-4945 bound CK2 alpha from C. neoformans
Descriptor: 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid, Casein kinase II subunit alpha, SULFATE ION
Authors:Cho, H.S.
Deposit date:2018-11-16
Release date:2019-11-20
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of CX-4945 bound CK2 alpha from C. neoformans
To be published

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