6FGU
Crystal Structure of BAZ2B bromodomain in complex with 1-methylpyridinone compound 4
Summary for 6FGU
| Entry DOI | 10.2210/pdb6fgu/pdb |
| Related | 6FG6 6FGF 6FGG 6FGH 6FGI 6FGT |
| Descriptor | Bromodomain adjacent to zinc finger domain protein 2B, 1-methyl-6-oxidanylidene-~{N}-(2-pyrrolidin-1-ylethyl)pyridine-3-carboxamide (3 entities in total) |
| Functional Keywords | four helical bundle, transcription |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 13867.96 |
| Authors | Dalle Vedove, A.,Spiliotopoulos, D.,Lolli, G.,Caflisch, A. (deposition date: 2018-01-11, release date: 2018-05-30, Last modification date: 2024-01-17) |
| Primary citation | Dalle Vedove, A.,Spiliotopoulos, D.,D'Agostino, V.G.,Marchand, J.R.,Unzue, A.,Nevado, C.,Lolli, G.,Caflisch, A. Structural Analysis of Small-Molecule Binding to the BAZ2A and BAZ2B Bromodomains. ChemMedChem, 13:1479-1487, 2018 Cited by PubMed: 29770599DOI: 10.1002/cmdc.201800234 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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