8DWC
 
 | | CryoEM structure of Gq-coupled MRGPRX1 with peptide agonist BAM8-22 | | 分子名称: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Liu, Y, Cao, C, Fay, J.F, Roth, B.L. | | 登録日 | 2022-08-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (2.87 Å) | | 主引用文献 | Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Nat.Chem.Biol., 19, 2023
|
|
8DWH
 | | CryoEM structure of Gq-coupled MRGPRX1 with ligand Compound-16 | | 分子名称: | Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Liu, Y, Cao, C, Fay, J.F, Roth, B.L. | | 登録日 | 2022-08-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Nat.Chem.Biol., 19, 2023
|
|
8DWG
 | | CryoEM structure of Gq-coupled MRGPRX1 with peptide ligand BAM8-22 and positive allosteric modulator ML382 | | 分子名称: | 2-[(cyclopropanesulfonyl)amino]-N-(2-ethoxyphenyl)benzamide, Gs-mini-Gq chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Liu, Y, Cao, C, Fay, J.F, Roth, B.L. | | 登録日 | 2022-08-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (2.71 Å) | | 主引用文献 | Ligand recognition and allosteric modulation of the human MRGPRX1 receptor.
Nat.Chem.Biol., 19, 2023
|
|
3SEC
 | |
5F3W
 | | Structure of the ATPrS-Mre11/Rad50-DNA complex | | 分子名称: | 27-MER DNA, DNA double-strand break repair Rad50 ATPase,DNA double-strand break repair Rad50 ATPase, DNA double-strand break repair protein Mre11, ... | | 著者 | Liu, Y. | | 登録日 | 2015-12-03 | | 公開日 | 2016-03-02 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.11 Å) | | 主引用文献 | ATP-dependent DNA binding, unwinding, and resection by the Mre11/Rad50 complex
Embo J., 35, 2016
|
|
3DBP
 | | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP | | 分子名称: | 6-AMINOURIDINE 5'-MONOPHOSPHATE, Orotidine 5'-phosphate decarboxylase, SULFATE ION | | 著者 | Liu, Y, To, T, Bello, A.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2008-06-02 | | 公開日 | 2009-06-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of Human Orotidine 5'-Monophosphate Decarboxylase Complexed with 6-NH2-UMP
To be Published
|
|
1WQ6
 | | The tetramer structure of the nervy homolgy two (NHR2) domain of AML1-ETO is critical for AML1-ETO'S activity | | 分子名称: | AML1-ETO | | 著者 | Liu, Y, Cheney, M.D, Chruszcz, M, Lukasik, S.M, Hartman, K.L, Laue, T.M, Dauter, Z, Minor, W, Speck, N.A, Bushweller, J.H. | | 登録日 | 2004-09-23 | | 公開日 | 2005-10-04 | | 最終更新日 | 2022-04-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity
Cancer Cell, 9, 2006
|
|
1YQE
 | | Crystal Structure of Conserved Protein of Unknown Function AF0625 | | 分子名称: | Hypothetical UPF0204 protein AF0625, PYROPHOSPHATE 2- | | 著者 | Liu, Y, Skarina, T, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-02-01 | | 公開日 | 2005-03-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Crystal Structure of Conserved Hypothetical Protein AF0625
To be Published
|
|
1YXO
 | | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593 | | 分子名称: | 4-hydroxythreonine-4-phosphate dehydrogenase 1, ETHANOL, MAGNESIUM ION | | 著者 | Liu, Y, Xu, X, Dong, A, Kudritskam, M, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-02-22 | | 公開日 | 2005-04-05 | | 最終更新日 | 2011-10-05 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Crystal Structure of pyridoxal phosphate biosynthetic protein PdxA PA0593
To be Published
|
|
2AJG
 | | Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase | | 分子名称: | Leucyl-tRNA synthetase | | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | | 登録日 | 2005-08-01 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination
Biochem.J., 394, 2006
|
|
2AJH
 | | Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine | | 分子名称: | Leucyl-tRNA synthetase, METHIONINE | | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | | 登録日 | 2005-08-02 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination
Biochem.J., 394, 2006
|
|
2AJI
 | | Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with isoleucine | | 分子名称: | ISOLEUCINE, Leucyl-tRNA synthetase | | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | | 登録日 | 2005-08-02 | | 公開日 | 2006-01-24 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination
Biochem.J., 394, 2006
|
|
2AZP
 | | Crystal Structure of PA1268 Solved by Sulfur SAD | | 分子名称: | hypothetical protein PA1268 | | 著者 | Liu, Y, Gorodichtchenskaia, E, Skarina, T, Yang, C, Joachimiak, A, Edwards, A, Pai, E.F, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-09-12 | | 公開日 | 2005-12-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | Crystal Structure of PA1268 Solved by Sulfur SAD
To be Published
|
|
3MW7
 | |
3N2M
 | | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), ... | | 著者 | Liu, Y, Kotra, L.P, Pai, E.F. | | 登録日 | 2010-05-18 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP
To be Published
|
|
3N34
 | | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP | | 分子名称: | 1,2-ETHANEDIOL, 6-amino-5-fluorouridine 5'-(dihydrogen phosphate), DI(HYDROXYETHYL)ETHER, ... | | 著者 | Liu, Y, Kotra, L.P, Pai, E.F. | | 登録日 | 2010-05-19 | | 公開日 | 2011-04-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of Plasmodium falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP, produced from 5-fluoro-6-azido-UMP
To be Published
|
|
3MWA
 | |
3N3M
 | |
4RR5
 | |
2EAW
 | |
2ESH
 | | Crystal Structure of Conserved Protein of Unknown Function TM0937- a Potential Transcriptional Factor | | 分子名称: | CALCIUM ION, conserved hypothetical protein TM0937 | | 著者 | Liu, Y, Bochkareva, E, Zheng, H, Xu, X, Nocek, B, Lunin, V, Edward, A, Pai, E.F, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2005-10-26 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal Structure of Conserved Hypothetical Protein TM0937
To be Published
|
|
2FRH
 | | Crystal Structure of Sara, A Transcription Regulator From Staphylococcus Aureus | | 分子名称: | CALCIUM ION, Staphylococcal accessory regulator A | | 著者 | Liu, Y, Manna, A.C, Ingavale, S, Cheung, A.L, Zhang, G. | | 登録日 | 2006-01-19 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
4M9E
 | | Structure of Klf4 zinc finger DNA binding domain in complex with methylated DNA | | 分子名称: | ACETATE ION, DNA (5'-D(*GP*AP*GP*GP*(5CM)P*GP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*(5CM)P*GP*CP*CP*TP*C)-3'), ... | | 著者 | Liu, Y, Olanrewaju, Y.O, Blumenthal, R.M, Zhang, X, Cheng, X. | | 登録日 | 2013-08-14 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | | 主引用文献 | Structural basis for Klf4 recognition of methylated DNA.
Nucleic Acids Res., 42, 2014
|
|
2FNP
 | | Crystal structure of SarA | | 分子名称: | Staphylococcal accessory regulator A | | 著者 | Liu, Y, Manna, A.C, Pan, C.H, Cheung, A.L, Zhang, G. | | 登録日 | 2006-01-11 | | 公開日 | 2006-01-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and function analyses of the global regulatory protein SarA from Staphylococcus aureus.
Proc.Natl.Acad.Sci.Usa, 103, 2006
|
|
2GJ2
 | | Crystal Structure of VP9 from White Spot Syndrome Virus | | 分子名称: | CADMIUM ION, wsv230 | | 著者 | Liu, Y, Wu, J.L, Song, J.X, Sivaraman, J, Hew, C.L. | | 登録日 | 2006-03-30 | | 公開日 | 2006-09-19 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Identification of a Novel Nonstructural Protein, VP9, from White Spot Syndrome Virus: Its Structure Reveals a Ferredoxin Fold with Specific Metal Binding Sites
J.Virol., 80, 2006
|
|
