6N7V
 
 | | Structure of bacteriophage T7 gp4 (helicase-primase, E343Q mutant) in complex with ssDNA, dTTP, AC dinucleotide, and CTP (from multiple lead complexes) | | Descriptor: | DNA (93-MER), DNA primase/helicase, MAGNESIUM ION, ... | | Authors: | Gao, Y, Fox, T, Val, N, Yang, W. | | Deposit date: | 2018-11-28 | | Release date: | 2019-03-06 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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6N9W
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2) | | Descriptor: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | | Authors: | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | Deposit date: | 2018-12-04 | | Release date: | 2019-03-06 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (4 Å) | | Cite: | Structures and operating principles of the replisome.
Science, 363, 2019
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8H3T
 | | The crystal structure of AlpH | | Descriptor: | AlpH, GLYCEROL | | Authors: | Zhao, Y, Li, M, Jiang, M, Pan, L.F. | | Deposit date: | 2022-10-09 | | Release date: | 2023-09-13 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.866 Å) | | Cite: | O-methyltransferase-like enzyme catalyzed diazo installation in polyketide biosynthesis.
Nat Commun, 14, 2023
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8I4Y
 | | CalA3 complex structure with amidation product | | Descriptor: | 11-oxidanylidene-11-(1~{H}-pyrrol-2-yl)undecanoic acid, 3-HYDROXYANTHRANILIC ACID, Beta-ketoacyl-acyl-carrier-protein synthase I | | Authors: | Wang, J, Wang, Z. | | Deposit date: | 2023-01-21 | | Release date: | 2023-02-22 | | Last modified: | 2023-04-19 | | Method: | ELECTRON MICROSCOPY (3.84 Å) | | Cite: | C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
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8I4Z
 | | CalA3 with hydrolysis product | | Descriptor: | 11-oxidanylidene-11-(1~{H}-pyrrol-2-yl)undecanoic acid, Beta-ketoacyl-acyl-carrier-protein synthase I | | Authors: | Wang, J, Wang, Z. | | Deposit date: | 2023-01-21 | | Release date: | 2023-02-22 | | Last modified: | 2023-04-19 | | Method: | ELECTRON MICROSCOPY (3.97 Å) | | Cite: | C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
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8HVR
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8JKE
 | | AfsR(T337A) transcription activation complex | | Descriptor: | DNA(65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | Authors: | Wang, Y, Zheng, J. | | Deposit date: | 2023-06-01 | | Release date: | 2024-02-14 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Structural and functional characterization of AfsR, an SARP family transcriptional activator of antibiotic biosynthesis in Streptomyces.
Plos Biol., 22, 2024
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5W84
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5XWW
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5XWV
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6BJJ
 | | Human ABO(H) blood group glycosyltransferase GTB D302A mutant | | Descriptor: | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) | | Authors: | Gagnon, S.M.L, Legg, M.S.G, Evans, S.V. | | Deposit date: | 2017-11-06 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
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6BJI
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6BJK
 | | Human ABO(H) blood group glycosyltransferase GTB D302C mutant | | Descriptor: | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ... | | Authors: | Gagnon, S.M.L, Legg, M.S.G, Evans, S.V. | | Deposit date: | 2017-11-06 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
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6BJL
 | | Human ABO(H) blood group glycosyltransferase GTB D302L mutant | | Descriptor: | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ... | | Authors: | Gagnon, S.M.L, Legg, M.S.G, Evans, S.V. | | Deposit date: | 2017-11-06 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
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6BJM
 | | Human ABO(H) blood group glycosyltransferase GTB R188K mutant | | Descriptor: | ABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase), ... | | Authors: | Gagnon, S.M.L, Legg, M.S.G, Evans, S.V. | | Deposit date: | 2017-11-06 | | Release date: | 2018-09-19 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28, 2018
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7VO0
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7VPD
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7VPZ
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7VO9
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7VWK
 | | The product template domain of AviM | | Descriptor: | Polyketide synthase | | Authors: | Feng, Y, Yang, X, Zheng, J. | | Deposit date: | 2021-11-10 | | Release date: | 2022-06-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Streptomyces viridochromogenes product template domain represents an evolutionary intermediate between dehydratase and aldol cyclase of type I polyketide synthases.
Commun Biol, 5, 2022
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7WVZ
 | | CalA3_modular PKS_KS-AT-DH-KR | | Descriptor: | Beta-ketoacyl-acyl-carrier-protein synthase I | | Authors: | Wang, J, Wang, Z. | | Deposit date: | 2022-02-12 | | Release date: | 2023-02-22 | | Last modified: | 2023-10-11 | | Method: | ELECTRON MICROSCOPY (3.38 Å) | | Cite: | C-N bond formation by a polyketide synthase.
Nat Commun, 14, 2023
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7X76
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7X75
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7X74
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