6BJI

Human ABO(H) blood group glycosyltransferase GTA D302C mutant

Summary for 6BJI

• Entry DOI: 10.2210/pdb6bji/pdb
• Descriptor: Histo-blood group ABO system transferase, GLYCEROL (3 entities in total)
• Functional Keywords: blood group transferases, glycosyltransferases, enzymes, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 34403.76

Authors

Gagnon, S.M.L.,Legg, M.S.G.,Evans, S.V. (deposition date: 2017-11-06, release date: 2018-09-19, Last modification date: 2023-10-04)

• Primary citation: Gagnon, S.M.L.,Legg, M.S.G.,Polakowski, R.,Letts, J.A.,Persson, M.,Lin, S.,Zheng, R.B.,Rempel, B.,Schuman, B.,Haji-Ghassemi, O.,Borisova, S.N.,Palcic, M.M.,Evans, S.V.; Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.; Glycobiology, 28:624-636, 2018; PubMed: 29873711; DOI: 10.1093/glycob/cwy051

Experimental method

X-RAY DIFFRACTION (1.54 Å)