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6BJJ

Human ABO(H) blood group glycosyltransferase GTB D302A mutant

Summary for 6BJJ
Entry DOI10.2210/pdb6bjj/pdb
DescriptorABO blood group (Transferase A, alpha 1-3-N-acetylgalactosaminyltransferase transferase B, alpha 1-3-galactosyltransferase) (2 entities in total)
Functional Keywordsblood group transferases, glycosyltransferases, enzymes, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight34241.55
Authors
Gagnon, S.M.L.,Legg, M.S.G.,Evans, S.V. (deposition date: 2017-11-06, release date: 2018-09-19, Last modification date: 2023-10-04)
Primary citationGagnon, S.M.L.,Legg, M.S.G.,Polakowski, R.,Letts, J.A.,Persson, M.,Lin, S.,Zheng, R.B.,Rempel, B.,Schuman, B.,Haji-Ghassemi, O.,Borisova, S.N.,Palcic, M.M.,Evans, S.V.
Conserved residues Arg188 and Asp302 are critical for active site organization and catalysis in human ABO(H) blood group A and B glycosyltransferases.
Glycobiology, 28:624-636, 2018
Cited by
PubMed: 29873711
DOI: 10.1093/glycob/cwy051
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.45 Å)
Structure validation

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