6NZQ
 
 | |
6NZH
 | |
6NZF
 | |
6NZE
 | |
6NZP
 | |
4ETW
 | | Structure of the Enzyme-ACP Substrate Gatekeeper Complex Required for Biotin Synthesis | | 分子名称: | Acyl carrier protein, Pimelyl-[acyl-carrier protein] methyl ester esterase, methyl 7-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxoheptanoate | | 著者 | Agarwal, V, Nair, S.K. | | 登録日 | 2012-04-24 | | 公開日 | 2012-10-17 | | 最終更新日 | 2019-07-17 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis.
Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
6JHY
 | |
4FGY
 | | Identification of a unique PPAR ligand with an unexpected binding mode and antibetic activity | | 分子名称: | (4R,6S,8S,12R,14R,16Z,18R,19R,20S,21S)-19,21-dihydroxy-22-{(2S,2'R,5S,5'S)-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyloctahydro-2,2'-bifuran-5-yl}-4,6,8,12,14,18,20-heptamethyl-9,11-dioxodocos-16-enoic acid, Nuclear receptor coactivator 1, Peroxisome proliferator-activated receptor gamma | | 著者 | Wang, R, Li, Y. | | 登録日 | 2012-06-05 | | 公開日 | 2013-03-20 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Identification of the antibiotic ionomycin as an unexpected peroxisome proliferator-activated receptor Gamma (PPAR-gamma) ligand with a unique binding mode and effective glucose-lowering activity in a mouse model of diabetes.
Diabetologia, 56, 2013
|
|
7VPW
 | |
3WOH
 | |
5HDP
 | | Hydrolase StnA mutant - S185A | | 分子名称: | Hydrolase, methyl 5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(2-hydroxy-3-methoxyphenyl)-3-methylpyridine-2-carboxylate | | 著者 | Qian, T. | | 登録日 | 2016-01-05 | | 公開日 | 2017-01-11 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal Structure of StnA for the Biosynthesis of Antitumor Drug Streptonigrin Reveals a Unique Substrate Binding Mode
Sci Rep, 7, 2017
|
|
5HDF
 | | Hydrolase SeMet-StnA | | 分子名称: | Hydrolase | | 著者 | Qian, T. | | 登録日 | 2016-01-05 | | 公開日 | 2017-01-11 | | 最終更新日 | 2017-01-25 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Crystal Structure of StnA for the Biosynthesis of Antitumor Drug Streptonigrin Reveals a Unique Substrate Binding Mode
Sci Rep, 7, 2017
|
|
4N7L
 | |
5V8K
 | | Homodimeric reaction center of H. modesticaldum | | 分子名称: | 1-[GLYCEROLYLPHOSPHONYL]-2-[8-(2-HEXYL-CYCLOPROPYL)-OCTANAL-1-YL]-3-[HEXADECANAL-1-YL]-GLYCEROL, 4,4'-Diaponeurosporene, 8(1)-OH-Chlorophyll aF, ... | | 著者 | Gisriel, C, Sarrou, I, Ferlez, B, Golbeck, J, Redding, K.E, Fromme, R. | | 登録日 | 2017-03-22 | | 公開日 | 2017-09-06 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a symmetric photosynthetic reaction center-photosystem.
Science, 357, 2017
|
|
4KFW
 | |
4KFV
 | |
4N7K
 | | Zinc Substituted Reaction Center of the Rhodobacter sphaeroides | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, CARDIOLIPIN, FE (III) ION, ... | | 著者 | Hardjasa, A, Murphy, M.E.P. | | 登録日 | 2013-10-15 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural and kinetic properties of Rhodobacter sphaeroides photosynthetic reaction centers containing exclusively Zn-coordinated bacteriochlorophyll as bacteriochlorin cofactors.
Biochim.Biophys.Acta, 1837, 2013
|
|
6N7W
 | | Structure of bacteriophage T7 leading-strand DNA polymerase (D5A/E7A)/Trx in complex with a DNA fork and incoming dTTP (from multiple lead complexes) | | 分子名称: | DNA (25-MER), DNA (77-MER), DNA-directed DNA polymerase, ... | | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | | 登録日 | 2018-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N9V
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1) | | 分子名称: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | | 登録日 | 2018-12-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N7I
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (gp4(5)-DNA) | | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-27 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N9U
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1) | | 分子名称: | DNA (44-MER), DNA primase/helicase, DNA-directed DNA polymerase, ... | | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | | 登録日 | 2018-12-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N9X
 | | Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3) | | 分子名称: | DNA primase/helicase, DNA-directed DNA polymerase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Fox, T, Val, N, Yang, W. | | 登録日 | 2018-12-04 | | 公開日 | 2019-03-06 | | 最終更新日 | 2019-12-18 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N7T
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form III) | | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N7S
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form II) | | 分子名称: | DNA (25-MER), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
6N7N
 | | Structure of bacteriophage T7 E343Q mutant gp4 helicase-primase in complex with ssDNA, dTTP, AC dinucleotide and CTP (form I) | | 分子名称: | DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA primase/helicase, MAGNESIUM ION, ... | | 著者 | Gao, Y, Cui, Y, Zhou, Z, Yang, W. | | 登録日 | 2018-11-27 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structures and operating principles of the replisome.
Science, 363, 2019
|
|
