5HDP

Hydrolase StnA mutant - S185A

Summary for 5HDP

• Entry DOI: 10.2210/pdb5hdp/pdb
• Related: 5HDF
• Descriptor: Hydrolase, methyl 5-amino-6-(7-amino-6-methoxy-5,8-dioxo-5,8-dihydroquinolin-2-yl)-4-(2-hydroxy-3-methoxyphenyl)-3-methylpyridine-2-carboxylate (3 entities in total)
• Functional Keywords: hydrolase, complex
• Biological source: Streptomyces flocculus
• Total number of polymer chains: 7
• Total formula weight: 290319.92

Authors

Qian, T. (deposition date: 2016-01-05, release date: 2017-01-11, Last modification date: 2023-11-08)

• Primary citation: Qian, T.,Wo, J.,Zhang, Y.,Song, Q.,Feng, G.,Luo, R.,Lin, S.,Wu, G.,Chen, H.F.; Crystal Structure of StnA for the Biosynthesis of Antitumor Drug Streptonigrin Reveals a Unique Substrate Binding Mode; Sci Rep, 7:40254-40254, 2017; PubMed: 28074848; DOI: 10.1038/srep40254

Experimental method

X-RAY DIFFRACTION (2.9 Å)