6MHZ
| Vanadate trapped Cryo-EM Structure of E.coli LptB2FG Transporter | Descriptor: | ADP ORTHOVANADATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | Authors: | Orlando, B.J, Li, Y, Liao, M. | Deposit date: | 2018-09-18 | Release date: | 2019-04-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex. Nature, 567, 2019
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6MI7
| Nucleotide-free Cryo-EM Structure of E.coli LptB2FGC | Descriptor: | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, Lipopolysaccharide export system ATP-binding protein LptB, Lipopolysaccharide export system permease protein LptF, ... | Authors: | Orlando, B.J, Li, Y, Liao, M. | Deposit date: | 2018-09-19 | Release date: | 2019-04-03 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural basis of lipopolysaccharide extraction by the LptB2FGC complex. Nature, 567, 2019
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6WTD
| Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of Bedaquiline bound | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | Authors: | Mueller, D.M, Srivastava, A.P, Symersky, J, Luo, M, Liao, M.F. | Deposit date: | 2020-05-02 | Release date: | 2020-08-26 | Last modified: | 2020-10-07 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Bedaquiline inhibits the yeast and human mitochondrial ATP synthases. Commun Biol, 3, 2020
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4W8F
| Crystal structure of the dynein motor domain in the AMPPNP-bound state | Descriptor: | Dynein heavy chain lysozyme chimera, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Cheng, H.-C, Bhabha, G, Zhang, N, Vale, R.D. | Deposit date: | 2014-08-24 | Release date: | 2014-11-12 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.541 Å) | Cite: | Allosteric communication in the Dynein motor domain. Cell, 159, 2014
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6NPK
| Structure of the TM domain | Descriptor: | Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2019-08-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NPJ
| Structure of the NKCC1 CTD | Descriptor: | Sodium-potassium-chloride cotransporter 1 | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NPL
| Cryo-EM structure of NKCC1 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2019-08-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NPH
| Structure of NKCC1 TM domain | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | Authors: | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | Deposit date: | 2019-01-17 | Release date: | 2019-07-31 | Last modified: | 2020-01-29 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6CP5
| Monomer yeast ATP synthase Fo reconstituted in nanodisc with inhibitor of oligomycin bound generated from focused refinement. | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6CP3
| Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc with inhibitor of oligomycin bound. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6WDO
| Cryo-EM structure of mitochondrial calcium uniporter holocomplex in high Ca2+ | Descriptor: | CALCIUM ION, Calcium uniporter protein, mitochondrial, ... | Authors: | Feng, L, Zhang, J, Fan, M. | Deposit date: | 2020-04-01 | Release date: | 2020-05-27 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
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6WDN
| Cryo-EM structure of mitochondrial calcium uniporter holocomplex in low Ca2+ | Descriptor: | Calcium uniporter protein, mitochondrial, Calcium uptake protein 1, ... | Authors: | Feng, L, Zhang, J, Fan, M. | Deposit date: | 2020-04-01 | Release date: | 2020-05-27 | Last modified: | 2020-06-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure and mechanism of the mitochondrial Ca2+uniporter holocomplex. Nature, 582, 2020
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6VK3
| CryoEM structure of Hrd3/Yos9 complex | Descriptor: | Hrd3, Protein OS-9 homolog | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2020-05-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJZ
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 complex of the expected topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK1
| CryoEM structure of Hrd1/Hrd3 part from Hrd1-Usa1/Der1/Hrd3 complex | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VK0
| CryoEM structure of Hrd1-Usa1/Der1/Hrd3 of the flipped topology | Descriptor: | Degradation in the endoplasmic reticulum protein 1, ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3, ... | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6VJY
| Cryo-EM structure of Hrd1/Hrd3 monomer | Descriptor: | ERAD-associated E3 ubiquitin-protein ligase HRD1, ERAD-associated E3 ubiquitin-protein ligase component HRD3 | Authors: | Wu, X, Rapoport, T.A. | Deposit date: | 2020-01-18 | Release date: | 2020-04-29 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Structural basis of ER-associated protein degradation mediated by the Hrd1 ubiquitin ligase complex. Science, 368, 2020
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6CP6
| Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6CP7
| Monomer yeast ATP synthase Fo reconstituted in nanodisc generated from masked refinement. | Descriptor: | ATP synthase protein 8, ATP synthase subunit 4, mitochondrial, ... | Authors: | Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. | Deposit date: | 2018-03-13 | Release date: | 2018-04-11 | Last modified: | 2020-01-15 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
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6FXN
| Crystal structure of human BAFF in complex with Fab fragment of anti-BAFF antibody belimumab | Descriptor: | Tumor necrosis factor ligand superfamily member 13B, belimumab heavy chain, belimumab light chain | Authors: | Lammens, A, Maskos, K, Willen, L, Jiang, X, Schneider, P. | Deposit date: | 2018-03-09 | Release date: | 2018-04-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A loop region of BAFF controls B cell survival and regulates recognition by different inhibitors. Nat Commun, 9, 2018
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2Q6F
| Crystal structure of infectious bronchitis virus (IBV) main protease in complex with a Michael acceptor inhibitor N3 | Descriptor: | Infectious bronchitis virus (IBV) main protease, N-[(5-METHYLISOXAZOL-3-YL)CARBONYL]ALANYL-L-VALYL-N~1~-((1R,2Z)-4-(BENZYLOXY)-4-OXO-1-{[(3R)-2-OXOPYRROLIDIN-3-YL]METHYL}BUT-2-ENYL)-L-LEUCINAMIDE | Authors: | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | Deposit date: | 2007-06-05 | Release date: | 2008-02-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J.Virol., 82, 2008
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2Q6D
| Crystal structure of infectious bronchitis virus (IBV) main protease | Descriptor: | Infectious bronchitis virus (IBV) main protease | Authors: | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | Deposit date: | 2007-06-04 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J.Virol., 82, 2008
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2Q6G
| Crystal structure of SARS-CoV main protease H41A mutant in complex with an N-terminal substrate | Descriptor: | Polypeptide chain, severe acute respiratory syndrome coronavirus (SARS-CoV) | Authors: | Xue, X.Y, Yang, H.T, Xue, F, Bartlam, M, Rao, Z.H. | Deposit date: | 2007-06-05 | Release date: | 2008-02-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design. J.Virol., 82, 2008
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8I4T
| Structure of the asymmetric unit of SFTSV virion | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein | Authors: | Du, S, Peng, R, Qi, J, Li, C. | Deposit date: | 2023-01-21 | Release date: | 2023-09-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Cryo-EM structure of severe fever with thrombocytopenia syndrome virus. Nat Commun, 14, 2023
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8ILQ
| Structure of SFTSV Gn-Gc heterodimer | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein | Authors: | Du, S, Peng, R, Qi, J, Li, C. | Deposit date: | 2023-03-04 | Release date: | 2023-09-13 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Cryo-EM structure of severe fever with thrombocytopenia syndrome virus. Nat Commun, 14, 2023
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