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7XKJ
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BU of 7xkj by Molmil
Kras-G12D-GDP-MRTX1133 by FIB-MicroED
Descriptor: 4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol, GUANOSINE-5'-DIPHOSPHATE, KRAS proto-oncogene, ...
Authors:Li, X.M.
Deposit date:2022-04-19
Release date:2023-08-02
Last modified:2023-08-16
Method:ELECTRON CRYSTALLOGRAPHY (3 Å)
Cite:Kras-G12D-GDP-MRTX1133 by FIB-MicroED
To Be Published
3MCE
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BU of 3mce by Molmil
Crystal structure of the NAC domain of alpha subunit of nascent polypeptide-associated complex(NAC)
Descriptor: IODIDE ION, Nascent polypeptide-associated complex subunit alpha
Authors:Wang, L.F, Zhang, W.C, Wang, L, Zhang, X.J.C, Li, X.M, Rao, Z.
Deposit date:2010-03-29
Release date:2010-07-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.396 Å)
Cite:Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit
Protein Cell, 1, 2010
3MCB
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BU of 3mcb by Molmil
Crystal structure of NAC domains of human nascent polypeptide-associated complex (NAC)
Descriptor: IODIDE ION, Nascent polypeptide-associated complex subunit alpha, Transcription factor BTF3
Authors:Wang, L.F, Zhang, W.C, Wang, L, Zhang, X.J.C, Li, X.M, Rao, Z.
Deposit date:2010-03-29
Release date:2010-07-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of NAC domains of human nascent polypeptide-associated complex (NAC) and its alphaNAC subunit
Protein Cell, 1, 2010
4PR3
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BU of 4pr3 by Molmil
Crystal structure of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Descriptor: 5'-methylthioadenosine nucleosidase / s-adenosylhomocysteine nucleosidase, ADENINE, GLYCEROL, ...
Authors:Zhang, X.C, Kang, X.S, Zhao, Y, Jiang, D.H, Li, X.M, Chen, Z.L.
Deposit date:2014-03-05
Release date:2014-04-30
Method:X-RAY DIFFRACTION (2.606 Å)
Cite:Crystal structure and biochemical studies of Brucella melitensis 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase
Biochem.Biophys.Res.Commun., 446, 2014
7CQ7
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BU of 7cq7 by Molmil
Structure of the human CLCN7-OSTM1 complex with ADP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
Deposit date:2020-08-08
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Structure of the human CLCN7-OSTM1 complex with ADP
To Be Published
7CQ5
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BU of 7cq5 by Molmil
Structure of the human CLCN7-OSTM1 complex with ATP
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
Deposit date:2020-08-08
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structure of the human CLCN7-OSTM1 complex with ATP
To Be Published
7CQ6
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BU of 7cq6 by Molmil
Structure of the human CLCN7-OSTM1 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, H(+)/Cl(-) exchange transporter 7, ...
Authors:Yang, G.H, Lu, Y.M, Zhang, Y.M, Jia, Y.T, Li, X.M, Lei, J.L.
Deposit date:2020-08-08
Release date:2020-11-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure of the human CLCN7-OSTM1 complex
To Be Published
7ZL9
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BU of 7zl9 by Molmil
Crystal structure of human GPCR Niacin receptor (HCA2)
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DI(HYDROXYETHYL)ETHER, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, ...
Authors:Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, Han, G.W, FiBerto, J.F, Wu, L.J, Tong, J.H, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J.
Deposit date:2022-04-14
Release date:2023-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
7ZLY
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BU of 7zly by Molmil
Crystal structure of human GPCR Niacin receptor (HCA2) expressed from Spodoptera frugiperda
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Hydroxycarboxylic acid receptor 2,Soluble cytochrome b562, OLEIC ACID
Authors:Yang, Y, Kang, H.J, Gao, R.G, Wang, J.J, FiBerto, J.F, Wu, L.J, Tong, J.H, Han, G.W, Qu, L, Wu, Y.R, Pileski, R, Li, X.M, Zhang, X.C, Zhao, S.W, Kenakin, T, Wang, Q, Stevens, R.C, Peng, W, Roth, B.L, Rao, Z.H, Liu, Z.J.
Deposit date:2022-04-17
Release date:2023-04-12
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural insights into the human niacin receptor HCA2-G i signalling complex.
Nat Commun, 14, 2023
6ISO
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BU of 6iso by Molmil
Human SIRT3 Recognizing H3K4cr
Descriptor: (2E)-BUT-2-ENAL, ARG-THR-LYS-GLN-THR-ALA-ARG, GLYCEROL, ...
Authors:Wang, Y, Hao, Q.
Deposit date:2018-11-17
Release date:2019-01-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Identification of 'erasers' for lysine crotonylated histone marks using a chemical proteomics approach.
Elife, 3, 2014
3NX2
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BU of 3nx2 by Molmil
Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase in complex with substrate analogues
Descriptor: 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, Ferulic acid decarboxylase
Authors:Gu, W, Yang, J.K, Lou, Z.Y, Meng, Z.H, Zhang, K.-Q.
Deposit date:2010-07-12
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
Plos One, 6, 2011
3NX1
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BU of 3nx1 by Molmil
Crystal structure of Enterobacter sp. Px6-4 Ferulic Acid Decarboxylase
Descriptor: Ferulic acid decarboxylase
Authors:Gu, W, Yang, J.K, Lou, Z.Y, Meng, Z.H, Zhang, K.-Q.
Deposit date:2010-07-12
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Enzymatic Activity for the Ferulic Acid Decarboxylase (FADase) from Enterobacter sp. Px6-4
Plos One, 6, 2011
6IRO
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BU of 6iro by Molmil
the crosslinked complex of ISWI-nucleosome in the ADP-bound state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (167-MER), Histone H2A, ...
Authors:Yan, L.J, Wu, H, Li, X.M, Gao, N, Chen, Z.C.
Deposit date:2018-11-13
Release date:2019-04-03
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of the ISWI-nucleosome complex reveal a conserved mechanism of chromatin remodeling.
Nat. Struct. Mol. Biol., 26, 2019
8IA7
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BU of 8ia7 by Molmil
Structural insights into human brain gut peptide cholecystokinin receptors
Descriptor: CCK-8, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S.
Deposit date:2023-02-08
Release date:2023-12-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
7FCV
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BU of 7fcv by Molmil
Cryo-EM structure of the Potassium channel AKT1 mutant from Arabidopsis thaliana
Descriptor: PHOSPHATIDYLETHANOLAMINE, POTASSIUM ION, Potassium channel AKT1
Authors:Yang, G.H, Lu, Y.M, Jia, Y.T, Zhang, Y.M, Tang, R.F, Xu, X, Li, X.M, Lei, J.L.
Deposit date:2021-07-15
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis for the activity regulation of a potassium channel AKT1 from Arabidopsis.
Nat Commun, 13, 2022
3K2S
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BU of 3k2s by Molmil
Solution structure of double super helix model
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Apolipoprotein A-I, CHOLESTEROL
Authors:Wu, Z, Gogonea, V, Lee, X, Wagner, M.A, Li, X.-M, Huang, Y, Undurti, A, May, R.P, Haertlein, M, Moulin, M, Gutsche, I, Zaccai, G, Didonato, J.A, Hazen, L.S.
Deposit date:2009-09-30
Release date:2010-04-07
Last modified:2024-02-21
Method:SOLUTION SCATTERING
Cite:Double superhelix model of high density lipoprotein.
J.Biol.Chem., 284, 2009
3MTV
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BU of 3mtv by Molmil
The Crystal Structure of the PRRSV Nonstructural Protein Nsp1
Descriptor: Papain-like cysteine protease
Authors:Xue, F, Sun, Y.N, Yan, L.M, Zhao, C, Lou, Z.Y, Rao, Z.H.
Deposit date:2010-04-30
Release date:2010-05-19
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of porcine reproductive and respiratory syndrome virus nonstructural protein Nsp1beta reveals a novel metal-dependent nuclease
J.Virol., 84, 2010
5YYF
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BU of 5yyf by Molmil
Crystal structure of AF9 YEATS domain in complex with a peptide inhibitor "PHQ-H3(Q5-K9)" modified at K9 with 2-furancarboyl group
Descriptor: 2-FUROIC ACID, Peptide inhibitor PHQ-H3(Q5-K9), Protein AF-9, ...
Authors:Li, Y, Li, H.
Deposit date:2017-12-09
Release date:2018-11-07
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.903 Å)
Cite:Structure-guided development of YEATS domain inhibitors by targeting pi-pi-pi stacking.
Nat. Chem. Biol., 14, 2018
6L5Z
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BU of 6l5z by Molmil
Crystal strucutre of AF9 YEATS domain in complex with a cyclopeptide inhibitor
Descriptor: Protein AF-9, SC0-ALO-ALA-SC3-SC4-NH2
Authors:Li, Y, Chen, G, Li, H.
Deposit date:2019-10-25
Release date:2020-10-28
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Selective Targeting of AF9 YEATS Domain by Cyclopeptide Inhibitors with Preorganized Conformation.
J.Am.Chem.Soc., 142, 2020
7XOW
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BU of 7xow by Molmil
Structural insights into human brain gut peptide cholecystokinin receptors
Descriptor: Gastrin, Gastrin/cholecystokinin type B receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S.
Deposit date:2022-05-01
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
7XOU
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BU of 7xou by Molmil
Structural insights into human brain gut peptide cholecystokinin receptors
Descriptor: CCK-8, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S.
Deposit date:2022-05-01
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
7XOV
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BU of 7xov by Molmil
Structural insights into human brain gut peptide cholecystokinin receptors
Descriptor: 2-[2-[[4-(4-chloranyl-2,5-dimethoxy-phenyl)-5-(2-cyclohexylethyl)-1,3-thiazol-2-yl]carbamoyl]-5,7-dimethyl-indol-1-yl]ethanoic acid, Cholecystokinin receptor type A, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
Authors:Ding, Y, Zhang, H, Liao, Y, Chen, L, Ji, S.
Deposit date:2022-05-01
Release date:2022-07-20
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural insights into human brain-gut peptide cholecystokinin receptors.
Cell Discov, 8, 2022
7XWX
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BU of 7xwx by Molmil
Crystal structure of SARS-CoV-2 N-CTD
Descriptor: Nucleoprotein, PHOSPHATE ION
Authors:Luan, X.D, Li, X.M, Li, Y.F.
Deposit date:2022-05-27
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein.
Sci Bull (Beijing), 67, 2022
7XX1
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BU of 7xx1 by Molmil
Crystal structure of SARS-CoV-2 N-NTD
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoprotein, ZINC ION
Authors:Luan, X.D, Li, X.M, Li, Y.F.
Deposit date:2022-05-27
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein.
Sci Bull (Beijing), 67, 2022
7XWZ
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BU of 7xwz by Molmil
Crystal structure of SARS-CoV-2 N-NTD and dsRNA complex
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Nucleoprotein, ...
Authors:Luan, X.D, Li, X.M, Li, Y.F.
Deposit date:2022-05-27
Release date:2023-02-08
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein.
Sci Bull (Beijing), 67, 2022

 

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