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2HYI
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BU of 2hyi by Molmil
Structure of the human exon junction complex with a trapped DEAD-box helicase bound to RNA
Descriptor: 5'-R(*UP*UP*UP*UP*UP*U)-3', MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Andersen, C.B.F, Le Hir, H, Andersen, G.R.
Deposit date:2006-08-06
Release date:2006-08-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
2XB2
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BU of 2xb2 by Molmil
Crystal structure of the core Mago-Y14-eIF4AIII-Barentsz-UPF3b assembly shows how the EJC is bridged to the NMD machinery
Descriptor: EUKARYOTIC INITIATION FACTOR 4A-III, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
Authors:Buchwald, G, Ebert, J, Basquin, C, Sauliere, J, Jayachandran, U, Bono, F, Le Hir, H, Conti, E.
Deposit date:2010-04-03
Release date:2010-05-12
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Insights Into the Recruitment of the Nmd Machinery from the Crystal Structure of a Core Ejc-Upf3B Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010
2XZP
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BU of 2xzp by Molmil
Upf1 helicase
Descriptor: GLYCEROL, MALONATE ION, REGULATOR OF NONSENSE TRANSCRIPTS 1
Authors:Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZL
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BU of 2xzl by Molmil
Upf1-RNA complex
Descriptor: 5- R(*UP*UP*UP*UP*UP*UP*UP*UP*U) -3, ADENOSINE-5'-DIPHOSPHATE, ATP-DEPENDENT HELICASE NAM7, ...
Authors:Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
2XZO
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BU of 2xzo by Molmil
Upf1 helicase - RNA complex
Descriptor: 5'-R(*UP*UP*UP*UP*UP*UP*UP)-3', ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Chakrabarti, S, Jayachandran, U, Bonneau, F, Fiorini, F, Basquin, C, Domcke, S, Le Hir, H, Conti, E.
Deposit date:2010-11-26
Release date:2011-03-30
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.395 Å)
Cite:Molecular Mechanisms for the RNA-Dependent ATPase Activity of Upf1 and its Regulation by Upf2.
Mol.Cell, 41, 2011
4A6Q
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BU of 4a6q by Molmil
Crystal structure of mouse SAP18 residues 6-143
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, ISOPROPYL ALCOHOL
Authors:Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E.
Deposit date:2011-11-08
Release date:2012-03-07
Last modified:2015-03-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
4A8X
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BU of 4a8x by Molmil
Structure of the core ASAP complex
Descriptor: HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18, HOOK-LIKE, ISOFORM A, ...
Authors:Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E.
Deposit date:2011-11-21
Release date:2012-03-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
4A90
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BU of 4a90 by Molmil
Crystal structure of mouse SAP18 residues 1-143
Descriptor: GLYCEROL, HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18
Authors:Murachelli, A.G, Ebert, J, Basquin, C, Le Hir, H, Conti, E.
Deposit date:2011-11-22
Release date:2012-03-07
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Structure of the Asap Core Complex Reveals the Existence of a Pinin-Containing Psap Complex
Nat.Struct.Mol.Biol., 19, 2012
2HXY
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BU of 2hxy by Molmil
Crystal structure of human apo-eIF4AIII
Descriptor: Probable ATP-dependent RNA helicase DDX48
Authors:Johansen, J.S, Andersen, G.R.
Deposit date:2006-08-04
Release date:2006-08-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA.
Science, 313, 2006
6YVH
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BU of 6yvh by Molmil
CWC22-CWC27-EIF4A3 Complex
Descriptor: Eukaryotic initiation factor 4A-III, Pre-mRNA-splicing factor CWC22 homolog, Spliceosome-associated protein CWC27 homolog
Authors:Basquin, J, Busetto, V, LeHir, H, Conti, E.
Deposit date:2020-04-28
Release date:2020-05-13
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structural and functional insights into CWC27/CWC22 heterodimer linking the exon junction complex to spliceosomes.
Nucleic Acids Res., 48, 2020
4C9B
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BU of 4c9b by Molmil
Crystal structure of eIF4AIII-CWC22 complex
Descriptor: EUKARYOTIC INITIATION FACTOR 4A-III, GLYCEROL, PHOSPHATE ION, ...
Authors:Buchwald, G, Schuessler, S, Basquin, C, LeHir, H, Conti, E.
Deposit date:2013-10-02
Release date:2013-11-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of the Human Eif4Aiii-Cwc22 Complex Shows How a Dead-Box Protein is Inhibited by a Mif4G Domain
Proc.Natl.Acad.Sci.USA, 110, 2013
3EX7
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BU of 3ex7 by Molmil
The crystal structure of EJC in its transition state
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Eukaryotic initiation factor 4A-III, ...
Authors:Andersen, G.R, Nielsen, K.H.
Deposit date:2008-10-16
Release date:2008-12-09
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.301 Å)
Cite:Mechanism of ATP turnover inhibition in the EJC
Rna, 15, 2009
6EJ5
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BU of 6ej5 by Molmil
A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner
Descriptor: Regulator of nonsense transcripts 1
Authors:Gowravaram, M, Bonneau, F, Maciej, V.D, Chakrabarti, S.
Deposit date:2017-09-20
Release date:2018-01-24
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (3.34 Å)
Cite:A conserved structural element in the RNA helicase UPF1 regulates its catalytic activity in an isoform-specific manner.
Nucleic Acids Res., 46, 2018

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